Explore 22 Luxury Hotels in Downtown St. Louis

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Best Luxury Hotels in Downtown St. Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$425 nightly
The price is $497 total per night from Oct 31 to Nov 1
$497 total
Oct 31 - Nov 1
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...
9.4/10 Exceptional! (1,000 reviews)
The views from the pool were great as well as the access to the Spa with the whirlpool. Restaurant experience was underwhelming for a very nice hotel but it was kind of convenient although service was NOT fast or attentive. The room did have a comfortable bed. First room had a bath tub that was not ...

Reviewed on Oct 5, 2025

Opens in a new windowFour Seasons Hotel St Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $164 total per night from Nov 1 to Nov 2
$164 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
9.4/10 Exceptional! (3,192 reviews)
10/10
Very clean hotel. Location made many things walkable. Desk staff were friendly and beyond helpful. We had a refrigerator that wasn’t keeping our drinks cold and maintenance arrived to fix it immediately despite it being 8pm. Loved the 5:30 free drinks and food offerings. 10/10 recommend, and we will ...

Reviewed on Oct 21, 2025

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

2211 Market Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Nov 2 to Nov 3
$110 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8.8/10 Excellent! (1,682 reviews)
This was a great location for downtown area, especially union station! Comfy beds, great breakfast, drinks and popcorn in the lobby was nice too.

Reviewed on Oct 19, 2025

Opens in a new windowPear Tree Inn St. Louis Near Union Station
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St, St. Louis, MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $120 total per night from Nov 23 to Nov 24
$120 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.6/10 Excellent! (1,049 reviews)
The valet is why I gave a 4/5

Reviewed on Oct 20, 2025

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
Missouri Athletic Club

Missouri Athletic Club

405 Washington Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $163 total per night from Nov 5 to Nov 6
$163 total
Nov 5 - Nov 6
Total with taxes and fees
This hotel features 2 restaurants and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Self ...
8.6/10 Excellent! (1,000 reviews)
It was gorgeous! Wish I had know about the dress code for the lobby area….nothing to fancy, just not what we had brought with us! We will definitely be staying there again!

Reviewed on Oct 20, 2025

Opens in a new windowMissouri Athletic Club
The Westin St. Louis

The Westin St. Louis

811 Spruce St, St. Louis, MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Nov 23 to Nov 24
$138 total
Nov 23 - Nov 24
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.4/10 Very Good! (1,009 reviews)
Loved our stay
Very nice hotel close to everything. The staff is nice and friendly, the bar was nice and the bed was very comfortable. We will definitely be back!

Reviewed on Oct 5, 2025

Opens in a new windowThe Westin St. Louis
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

1820 Market Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $196 total per night from Nov 23 to Nov 24
$196 total
Nov 23 - Nov 24
Total with taxes and fees
This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free ...
8.4/10 Very Good! (1,016 reviews)
Amazing-Kind- Luxurious
Everyone was incredible, all staff was really friendly. We stayed for the Adam Sandler concert and it was a short walk over to the Enterprise Center. We also were comped a really nice breakfast because of a slight issue with our keys that was easily fixed. Amazing time!

Reviewed on Oct 18, 2025

Opens in a new windowSt. Louis Union Station Hotel, Curio Collection by Hilton
Le Meridien St. Louis Downtown

Le Meridien St. Louis Downtown

1019 Pine St, St. Louis, MO
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Amazing staff!
Unfortunately the pipes froze and broke right before we arrived at the hotel but the staff was amazing and relocated us and provided transportation to our new hotel. They went above and beyond and couldn’t have been nicer in spite of the challenging conditions that they were facing. We were sorry ...

Reviewed on Jan 25, 2024

Opens in a new windowLe Meridien St. Louis Downtown
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Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis, MO
$425 nightly
The price is $497 total per night from Oct 31 to Nov 1
$497 total
Oct 31 - Nov 1
Total with taxes and fees
9.4/10 Exceptional! (1,000 reviews)

Downtown St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Downtown St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Downtown St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Downtown St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Downtown St. Louis, and plan your next opulent escape.


Downtown St. Louis hotels essential information

Accommodation
571 hotels
Lowest Price
$110
Highest Price
$497
Popular hotels
Four Seasons Hotel St Louis, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, St. Louis Union Station Hotel, Curio Collection by Hilton, Missouri Athletic Club, Le Meridien St. Louis Downtown, Pear Tree Inn St. Louis Near Union Station

Popular Luxury Stays in Downtown St. Louis

Recent Downtown St. Louis Hotel Reviews By Fellow Wanderers

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