Explore 22 Luxury Hotels in Downtown St. Louis

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Best Luxury Hotels in Downtown St. Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis, MO

Fully refundableReserve now, pay when you stay

$495 nightly

$579 total

Jul 27 - Jul 28

Total includes taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...

9.4/10 Exceptional! (1,004 reviews)

"Great hotel, loved the room"

Reviewed on Jul 19, 2025

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street, St. Louis, MO

Fully refundableReserve now, pay when you stay

$140 nightly

$164 total

Jul 31 - Aug 1

Total includes taxes and fees

This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

9.4/10 Exceptional! (2,871 reviews)

"Very close to everything and the excellent happy hour. What was bad was the elevators--very slow and only two out of three worked."

Reviewed on Jul 21, 2025

Pear Tree Inn St. Louis Near Union Station

2211 Market Street, St. Louis, MO

Fully refundableReserve now, pay when you stay

$101 nightly

$118 total

Aug 24 - Aug 25

Total includes taxes and fees

This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

8.8/10 Excellent! (1,512 reviews)

Comfort Overnight.

"Convenient location to Union Station. Good place for families. Room was comfortable and clean with fluffy pillows. Free breakfast with snacks in the evening. Price is budget friendly. Here for an overnight stay for a doctor's appointment in the morning. Will definitely be back."

Reviewed on Jul 21, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St, St. Louis, MO

Fully refundableReserve now, pay when you stay

$103 nightly

$122 total

Aug 3 - Aug 4

Total includes taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

8.6/10 Excellent! (1,015 reviews)

"The staff was very helpful. The building has a lot of charm. I would stay there again."

Reviewed on Jul 22, 2025

Missouri Athletic Club

405 Washington Ave, St. Louis, MO

Fully refundableReserve now, pay when you stay

$130 nightly

$153 total

Aug 10 - Aug 11

Total includes taxes and fees

This hotel features 2 restaurants and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Self ...

8.6/10 Excellent! (1,008 reviews)

"Old unique building, reasonably priced and great location."

Reviewed on Jul 22, 2025

The Westin St. Louis

811 Spruce St, St. Louis, MO

Fully refundableReserve now, pay when you stay

$127 nightly

$148 total

Aug 3 - Aug 4

Total includes taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...

8.4/10 Very Good! (1,011 reviews)

Would recommend

"Check-in was wonderful! The room was spacious and comfortable. The bathroom maybe a little upgrade.. but still comfy! Orlando, the valet was just amazing!!!!! Give that man a raise! The bar staff, well just one man, was kind but not very energetic- (trying to be kind). But- stillWould ..."

Reviewed on Jul 20, 2025

St. Louis Union Station Hotel, Curio Collection by Hilton

1820 Market Street, St. Louis, MO

Fully refundableReserve now, pay when you stay

$191 nightly

$227 total

Jul 31 - Aug 1

Total includes taxes and fees

This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free ...

8.4/10 Very Good! (1,004 reviews)

"Loved our stay"

Reviewed on Jul 20, 2025

Le Meridien St. Louis Downtown

1019 Pine St, St. Louis, MO

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Amazing staff!

"Unfortunately the pipes froze and broke right before we arrived at the hotel but the staff was amazing and relocated us and provided transportation to our new hotel. They went above and beyond and couldn’t have been nicer in spite of the challenging conditions that they were facing. We were sorry ..."

Reviewed on Jan 25, 2024

Get rates

Don't see what you're looking for?

See all available properties in Downtown St. Louis

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Downtown St. Louis

Hilton Pennywell St. Louis at the Arch

400 Olive St, St. Louis, MO

$123 nightly

$145 total

Aug 3 - Aug 4

Total includes taxes and fees

8.8/10 Excellent! (853 reviews)

5 star hotels in Downtown St. Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis, MO

$495 nightly

$579 total

Jul 27 - Jul 28

Total includes taxes and fees

9.4/10 Exceptional! (1,004 reviews)

Downtown St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Downtown St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Downtown St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Downtown St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Downtown St. Louis, and plan your next opulent escape.

Downtown St. Louis hotels essential information

Accommodation	584 hotels
Lowest Price	$118
Highest Price	$579
Popular hotels	Four Seasons Hotel St Louis, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, St. Louis Union Station Hotel, Curio Collection by Hilton, Missouri Athletic Club, Le Meridien St. Louis Downtown, Pear Tree Inn St. Louis Near Union Station

Popular Luxury Stays in Downtown St. Louis

5 Stars Luxury stays in Downtown St. Louis

Luxury stays in Downtown St. Louis with spa

Recent Downtown St. Louis Hotel Reviews By Fellow Wanderers

Hilton St. Louis at the Ballpark

5 out of 5

Posted 23 hours ago

Travelocity Verified Review

"Staff was wonderful. Room was clean. Valet was great. Bar had good food and drinks. "

A verified traveler stayed at Hilton St. Louis at the Ballpark

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

5 out of 5

Posted 3 days ago

Travelocity Verified Review

"we went to St. Louis to see the arch and got a room with the view of the arch. We opened our curtains and went to sleep looking at thel lighted up arch! It was wonderful, the comfort of the bed was wonderful and the morning complementary breakfast was wonderful. We would totally stay here again."

A verified traveler stayed at Hampton Inn St. Louis-Downtown (At the Gateway Arch)