Explore 22 Luxury Hotels in Downtown St. Louis

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Best Luxury Hotels in Downtown St. Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $380 total per night from Mar 16 to Mar 17
$380 total
per night
Mar 16 - Mar 17
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...
9.4/10 Exceptional! (1,001 reviews)
Top notch in every way. From the moment you walk in, it’s what you would expect from a 5-Star Hotel. Highly recommended.

Reviewed on Mar 9, 2026

Opens in a new windowFour Seasons Hotel St Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $175 total per night from Mar 15 to Mar 16
$175 total
per night
Mar 15 - Mar 16
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
9.4/10 Exceptional! (3,347 reviews)
Clean room good view.

Reviewed on Mar 13, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $159 total per night from Mar 22 to Mar 23
$159 total
per night
Mar 22 - Mar 23
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.8/10 Excellent! (1,261 reviews)
Love the staff

Reviewed on Mar 13, 2026

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
Missouri Athletic Club

Missouri Athletic Club

405 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $168 total per night from Mar 24 to Mar 25
$168 total
per night
Mar 24 - Mar 25
This hotel features 2 restaurants and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Self ...
8.8/10 Excellent! (1,000 reviews)
Clean and friendly.

Reviewed on Mar 11, 2026

Opens in a new windowMissouri Athletic Club
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $124 total per night from Apr 5 to Apr 6
$124 total
per night
Apr 5 - Apr 6
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8.8/10 Excellent! (1,868 reviews)
Great location, minutes from every downtown St Louis attraction. Perfect for weekend getaways for couples or families. Happy hour was a plus!

Reviewed on Mar 13, 2026

Opens in a new windowPear Tree Inn St. Louis Near Union Station
The Westin St. Louis

The Westin St. Louis

811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $158 total per night from Apr 5 to Apr 6
$158 total
per night
Apr 5 - Apr 6
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.6/10 Excellent! (1,002 reviews)
Paid on expedia with my points and the hotel still charged my card the full room rate. Upon check in she even stated the room was already paid for. I had to call and get it reversed.

Reviewed on Mar 12, 2026

Opens in a new windowThe Westin St. Louis
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

1820 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $229 total per night from Mar 22 to Mar 23
$229 total
per night
Mar 22 - Mar 23
This luxury hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free WiFi. ...
8.6/10 Excellent! (1,001 reviews)
Clean rooms, staff was very helpful.

Reviewed on Mar 13, 2026

Opens in a new windowSt. Louis Union Station Hotel, Curio Collection by Hilton
Le Meridien St. Louis Downtown

Le Meridien St. Louis Downtown

1019 Pine St St. Louis MO
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.2/10 Very Good! (108 reviews)
Amazing staff!
Unfortunately the pipes froze and broke right before we arrived at the hotel but the staff was amazing and relocated us and provided transportation to our new hotel. They went above and beyond and couldn’t have been nicer in spite of the challenging conditions that they were facing. We were sorry ...

Reviewed on Jan 25, 2024

Opens in a new windowLe Meridien St. Louis Downtown
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5 star hotels in Downtown St. Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
The price is $380 total per night from Mar 16 to Mar 17
$380 total
per night
Mar 16 - Mar 17
9.4/10 Exceptional! (1,001 reviews)

Downtown St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Downtown St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Downtown St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Downtown St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Downtown St. Louis, and plan your next opulent escape.


Downtown St. Louis hotels essential information

Accommodation
599 hotels
Lowest Price
$124
Highest Price
$380
Popular hotels
Four Seasons Hotel St Louis, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, St. Louis Union Station Hotel, Curio Collection by Hilton, Missouri Athletic Club, Le Meridien St. Louis Downtown, Pear Tree Inn St. Louis Near Union Station

Popular Luxury Stays in Downtown St. Louis

Recent Downtown St. Louis Hotel Reviews By Fellow Wanderers

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