Deals on vacations and trips to De Soto

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De Soto flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
Downtown West
Price was $603, price is now $443 per person
$443
per person
Apr 23 - Apr 26
found 1 day ago
Roundtrip non-stop flight included
Tampa (TPA) to St. Louis (STL)
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the gym and conveniences like a 24-hour front desk and concierge services.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was $762, price is now $479 per person
$479
per person
Apr 24 - Apr 26
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to St. Louis (STL)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
Grand Center
Save 100% on your flight
Price was $756, price is now $530 per person
$530
per person
Apr 23 - Apr 26
found 1 day ago
Roundtrip non-stop flight included
Tampa (TPA) to St. Louis (STL)
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. There's a rooftop terrace on site, and a 24-hour front desk and a snack bar/deli are also provided.
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

3 out of 5
Downtown West
Save 100% on your flight
Price was $709, price is now $515 per person
$515
per person
Apr 23 - Apr 26
found 1 day ago
Roundtrip non-stop flight included
Tampa (TPA) to St. Louis (STL)
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Traveling on business? Take advantage of the 24-hour business center and valet parking. A snack bar/deli and a safe deposit box are also provided.
The Cheshire

The Cheshire

4 out of 5
Price was $652, price is now $498 per person
$498
per person
Apr 23 - Apr 26
found 1 day ago
Roundtrip non-stop flight included
Tampa (TPA) to St. Louis (STL)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free English breakfast each morning.

Top De Soto hotels deals

82 Acre Hobby Farm with Lincoln Log Cabin

82 Acre Hobby Farm with Lincoln Log Cabin

De Soto MO
Get rates
This cabin features a garden, laundry facilities, and barbecue grills.
Kitchen
Washer
Secluded cabin on private property

Secluded cabin on private property

De Soto MO
Get rates
This cabin features a garden, laundry facilities, and barbecue grills.
Kitchen
Washer
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 out of 5
1201 Drury Ln Arnold MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $104 total per night
$104 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St Farmington MO
Free Cancellation
Reserve now, pay when you stay
$58 nightly
The price is $66 total per night
$66 total
Mar 30 - Mar 31
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

2 out of 5
7555 State Hwy Y French Village MO
$134 nightly
The price is $144 total per night
$144 total
Mar 30 - Mar 31
Total with taxes and fees
This cabin includes express check-out and a virtual front desk. Take advantage of the free self parking.
Kitchen
Pet friendly
Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold

3 out of 5
3800 State Rt 141 Arnold MO
Free Cancellation
Reserve now, pay when you stay
$102 nightly
The price is $118 total per night
$118 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included
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See all available properties in De Soto
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Sunrise Lake Beach

Why not spend a lazy afternoon at Sunrise Lake Beach during your trip to De Soto?

Sunrise Lake Beach

Valle Lake Beach

Explore the great outdoors at Valle Lake Beach, a lovely green space in De Soto.

Valle Lake Beach

Victoria Glaces Conservation Area Trailhead

You can take time to visit Victoria Glaces Conservation Area Trailhead during your travels to De Soto.

Victoria Glaces Conservation Area Trailhead

Frequently asked questions

How much are vacation packages to De Soto?
Your travel daydreams can become a reality in De Soto from just $443. Our package deals include flights and hotels, so organizing your itinerary will be a piece of cake. The only thing you'll have to concentrate on is getting out there and having a great time.
How long should my De Soto vacation be?
Many people choose to spend about 2 nights in De Soto, but how long you stay is your call. If you want to check out all the fantastic things this place offers, why not hang around a while longer?
Where can I get the best vacation package deals for De Soto?
Find your dream escape at Travelocity. With access to 400 airline partners and a whopping 1,000,000 hotels around the world, selecting the perfect De Soto package deal couldn't be easier.
Why should I book my De Soto vacation package via Travelocity?
From enticing destinations to fun experiences, we have everything you need to satisfy your wanderlust. Our 24/7 support will also make sure you're being taken care of before, during and after your vacation. And don't stress if you spot a lower price on your booking, we'll match it. That's our Price Match Guarantee.
Can I save money on my De Soto car rental if I bundle it with a hotel or flight?
Combining your flight, hotel and car into a De Soto vacation package is a surefire way to land the best prices. Plus, having your own car rental gives you absolute freedom to find your way to all the landmarks you're hoping to check out. Sitting 40 mi away from De Soto, Busch Stadium is one place that should have a place on your itinerary. Fasten your seat belt and make a day trip of it.
Which airport is best for De Soto?
Flying into De Soto will see you landing at Lambert-St. Louis Intl. Airport (STL). It's roughly 45 mi north of the downtown area.
What is there to do in De Soto?
Victoria Glaces Conservation Area Trailhead deserves a spot on your travel itinerary. After you've checked off this well-known attraction, simply roam the streets of De Soto and learn what really makes this cool destination tick.
Where should I stay when visiting De Soto?
Many travelers choose to check in to the Holiday Inn Club Vacations Timber Creek Resort At De Soto. It's a great base for your De Soto getaway.

Photos of local treasures

Browse De Soto vacation photos for more inspiration

Kayaking down the Big River on a fall day!

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