Deals on vacations and trips to De Soto

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De Soto flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
The Principal Hotel

The Principal Hotel

3.5 out of 5
Save 100% on your flight
per person
Sep 18 - Sep 22
found 1 day ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
A restaurant and a gym are featured at this hotel. Free self parking, a coffee shop, and dry cleaning are also offered.
The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
per person
Sep 25 - Sep 30
found 7 hours ago
Roundtrip flight included
Charlotte (CLT) to St. Louis (STL)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free English breakfast each morning.
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
per person
Sep 25 - Sep 30
found 7 hours ago
Roundtrip flight included
Charlotte (CLT) to St. Louis (STL)
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the 24-hour gym and perks like free self parking.
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Save 100% on your flight
per person
Sep 25 - Sep 30
found 7 hours ago
Roundtrip flight included
Charlotte (CLT) to St. Louis (STL)
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.
The Knight Center at Washington University

The Knight Center at Washington University

2.5 out of 5
per person
Oct 7 - Oct 11
found 1 day ago
Roundtrip non-stop flight included
Seattle (SEA) to St. Louis (STL)
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Self parking and a coffee shop are also offered on site.

Top De Soto hotels deals

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
Free Cancellation
$161 nightly
The price is $172 total per night
$172 total
Aug 10 - Aug 11
Total includes taxes and fees
This aparthotel's 2 outdoor tennis courts and gym are among the featured amenities. There's fun for all ages with mini golf and a playground, and barbecue grills are available on site. Enjoy the seasonal outdoor pool and perks like free self parking.
Pool
Parking included
Pool, Lake & Patio: Sweeping De Soto Estate

Pool, Lake & Patio: Sweeping De Soto Estate

Get rates
This property features a garden, laundry facilities, and barbecue grills.
82 Acre Hobby Farm with Lincoln Log Cabin

82 Acre Hobby Farm with Lincoln Log Cabin

$248 nightly
The price is $257 total per night
$257 total
Aug 10 - Aug 11
Total includes taxes and fees
This cabin features a garden, laundry facilities, and barbecue grills.
Lakeside Private Villa | 5-Hole Golf On-Site

Lakeside Private Villa | 5-Hole Golf On-Site

4800 US Highway 67, Desoto, MO
Free Cancellation
$173 nightly
The price is $184 total per night
$184 total
Aug 10 - Aug 11
Total includes taxes and fees
A sauna is available at this villa.
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 out of 5
1201 Drury Ln, Arnold, MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $104 total per night
$104 total
Aug 5 - Aug 6
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St, Farmington, MO
Free Cancellation
Reserve now, pay when you stay
$56 nightly
The price is $64 total per night
$64 total
Aug 12 - Aug 13
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Sunrise Lake Beach

Why not spend a lazy afternoon at Sunrise Lake Beach during your trip to De Soto?

Sunrise Lake Beach

Big Lake

Commune with nature and explore the great outdoors at Big Lake during your travels in De Soto.

Big Lake

Victoria Glaces Conservation Area Trailhead

You can take time to visit Victoria Glaces Conservation Area Trailhead during your travels to De Soto.

Victoria Glaces Conservation Area Trailhead

Frequently asked questions

How much are vacation packages to De Soto?
Your travel daydreams can become a reality in De Soto from just $365. Our package deals include flights and hotels, so organizing your itinerary will be a piece of cake. The only thing you'll have to concentrate on is getting out there and having a great time.
How long should my De Soto vacation be?
Many people choose to spend about 2 nights in De Soto, but how long you stay is your call. If you want to check out all the fantastic things this place offers, why not hang around a while longer?
Where can I get the best vacation package deals for De Soto?
Find your dream escape at Travelocity. With access to 400 airline partners and a whopping 1,000,000 hotels around the world, selecting the perfect De Soto package deal couldn't be easier.
Why should I book my De Soto vacation package via Travelocity?
From enticing destinations to fun experiences, we have everything you need to satisfy your wanderlust. Our 24/7 support will also make sure you're being taken care of before, during and after your vacation. And don't stress if you spot a lower price on your booking, we'll match it. That's our Price Match Guarantee.
Can I save money on my De Soto car rental if I bundle it with a hotel or flight?
Combining your flight, hotel and car into a De Soto vacation package is a surefire way to land the best prices. Plus, having your own car rental gives you absolute freedom to find your way to all the landmarks you're hoping to check out. Sitting 40 mi away from De Soto, Busch Stadium is one place that should have a place on your itinerary. Fasten your seat belt and make a day trip of it.
Which airport is best for De Soto?
Flying into De Soto will see you landing at Lambert-St. Louis Intl. Airport (STL). It's roughly 45 mi north of the downtown area.
What is there to do in De Soto?
Victoria Glaces Conservation Area Trailhead deserves a spot on your travel itinerary. After you've checked off this well-known attraction, simply roam the streets of De Soto and learn what really makes this cool destination tick.
Where should I stay when visiting De Soto?
Many travelers choose to check in to the Holiday Inn Club Vacations Timber Creek Resort At De Soto. It's a great base for your De Soto getaway.

Photos of local treasures

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Photo by Jessica King
Photo by Jessica King