De Soto Vacation Packages 2026 from $308

De Soto flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

The West End

Central West End

$308

per person

Feb 20 - Feb 22

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

A 24-hour gym, self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A garden and express check-out are also provided.

Ameristar Casino Resort and Spa

$435

per person

Feb 20 - Feb 22

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.

The Knight Center at Washington University

$358

per person

Feb 20 - Feb 22

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Self parking and a coffee shop are also offered on site.

Aloft St. Louis Cortex

Central West End

$385

per person

Feb 20 - Feb 22

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

This hotel features an indoor pool and a bar/lounge. WiFi in public areas is free. A 24-hour business center, a coffee shop, and a snack bar/deli are also on offer.

MainStay Suites St. Louis - Galleria

$321

per person

Feb 20 - Feb 22

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. Free self parking, a free grocery shopping service, and a grocery/convenience store are also offered.

Top De Soto hotels deals

82 Acre Hobby Farm with Lincoln Log Cabin

De Soto MO

$265 nightly

$275 total

Jan 3 - Jan 4, 2026

Total with taxes and fees

This cabin features a garden, laundry facilities, and barbecue grills.

Kitchen

Washer

Secluded cabin on private property

De Soto MO

Get rates

This cabin features a garden, laundry facilities, and barbecue grills.

Kitchen

Washer

Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St Farmington MO

Free Cancellation

Reserve now, pay when you stay

$53 nightly

$60 total

Dec 26 - Dec 27

Total with taxes and fees

This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

Pear Tree Inn St. Louis Arnold

1201 Drury Ln Arnold MO

Free Cancellation

Reserve now, pay when you stay

$90 nightly

$104 total

Dec 25 - Dec 26

Total with taxes and fees

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

Drury Inn & Suites St. Louis Arnold

3800 State Rt 141 Arnold MO

Free Cancellation

Reserve now, pay when you stay

$123 nightly

$142 total

Dec 24 - Dec 25

Total with taxes and fees

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

Pool

Breakfast included

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

1001 Veterans Blvd Festus MO

Free Cancellation

Reserve now, pay when you stay

$93 nightly

$106 total

Jan 4 - Jan 5, 2026

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business center. There's a gym on site, and a 24-hour front desk and a convenience store are also provided.

Breakfast included

Pet friendly

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Sunrise Lake Beach

Why not spend a lazy afternoon at Sunrise Lake Beach during your trip to De Soto?

Big Lake

Commune with nature and explore the great outdoors at Big Lake during your travels in De Soto.

Valle Lake Beach

Explore the great outdoors at Valle Lake Beach, a lovely green space in De Soto.

Frequently asked questions

How much are vacation packages to De Soto?

Your travel daydreams can become a reality in De Soto from just $308. Our package deals include flights and hotels, so organizing your itinerary will be a piece of cake. The only thing you'll have to concentrate on is getting out there and having a great time.

How long should my De Soto vacation be?

Many people choose to spend about 2 nights in De Soto, but how long you stay is your call. If you want to check out all the fantastic things this place offers, why not hang around a while longer?

Where can I get the best vacation package deals for De Soto?

Find your dream escape at Travelocity. With access to 400 airline partners and a whopping 1,000,000 hotels around the world, selecting the perfect De Soto package deal couldn't be easier.

Why should I book my De Soto vacation package via Travelocity?

From enticing destinations to fun experiences, we have everything you need to satisfy your wanderlust. Our 24/7 support will also make sure you're being taken care of before, during and after your vacation. And don't stress if you spot a lower price on your booking, we'll match it. That's our Price Match Guarantee.

Can I save money on my De Soto car rental if I bundle it with a hotel or flight?

Combining your flight, hotel and car into a De Soto vacation package is a surefire way to land the best prices. Plus, having your own car rental gives you absolute freedom to find your way to all the landmarks you're hoping to check out. Sitting 40 mi away from De Soto, Busch Stadium is one place that should have a place on your itinerary. Fasten your seat belt and make a day trip of it.

Which airport is best for De Soto?

Flying into De Soto will see you landing at Lambert-St. Louis Intl. Airport (STL). It's roughly 45 mi north of the downtown area.

What is there to do in De Soto?

Victoria Glaces Conservation Area Trailhead deserves a spot on your travel itinerary. After you've checked off this well-known attraction, simply roam the streets of De Soto and learn what really makes this cool destination tick.

Where should I stay when visiting De Soto?

Many travelers choose to check in to the Holiday Inn Club Vacations Timber Creek Resort At De Soto. It's a great base for your De Soto getaway.