Book Hotels in Chaffee, MO
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Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"This Drury is so nice! The room was one of the nicest we've benn in and it cost less than orher hotel rooms thay weren't as nice. The happy hour was great!!! Would highly recommend this hotel to anyone looking for a bargin hotel rhat doesn't feel like a bargain."
Reviewed on Jun 16, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
Fully refundable
A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
Great stay
"It was wonderful. Pool and workout room was in great shape and centrally located. Breakfast was amazing and night time cookies and milk was a nice surprise that my daughter didn’t let me forget. The staff was all super nice and I’d definitely stay again if in the area."
Reviewed on Jun 9, 2025

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Who knew that we’d walk into Drury Inn after 9 hrs of driving and they would provide free dinner?! They called it an evening snack but it definitely functioned as dinner for us (salad, chili, barbecue sliders, Mac n cheese, hotdogs, soda, etc) and was such a relief not to have to go find dinner at ..."
Reviewed on Jun 17, 2025

The Riverview
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
This hotel features a casino and 2 restaurants. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like free self parking and WiFi in public ...
"Great property. I wasn’t there long, but it was clean and comfortable."
Reviewed on Jun 15, 2025

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"I like the location and convenience of being right off the hwy. It is worth the price!"
Reviewed on Jun 13, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
Fully refundableReserve now, pay when you stay
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Staff was friendly comfortable beds, in a nice quiet room. Room was clean."
Reviewed on Jun 14, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
A seasonal outdoor pool is featured at this hotel, along with free WiFi in public areas and express check-out. Staff at the 24-hour front desk can provide around-the-clock ...
"The location was good and many options for dining, close to the highway but parking was very limited. The room appeared clean but I did find a used soap bar in the shower, so that means the shower wasn't cleaned from the last person who stayed. The staff were so friendly and welcoming. I appreciated ..."
Reviewed on Jun 16, 2025

Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
"Clean and friendly"
Reviewed on Jun 16, 2025

Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd, Cape Girardeau, MO
Fully refundable
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self parking, ...
Nice Stay
"The stay was amazing and I loved the set-up. The only issue I had was the bed seemed to have been broke on one side but everything else was nice"
Reviewed on Jun 5, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Chaffee hotel reviews by fellow wanderers

Drury Inn & Suites Sikeston, MO
5 out of 5
Posted 19 hours ago
Travelocity Verified Review
"Who knew that we’d walk into Drury Inn after 9 hrs of driving and they would provide free dinner?! They called it an evening snack but it definitely functioned as dinner for us (salad, chili, barbecue sliders, Mac n cheese, hotdogs, soda, etc) and was such a relief not to have to go find dinner at another drive through restaurant after a very long day. This was a major bonus that will take me back!
Also, I loved that they had huge suites with a separate bedroom. The only thing that was difficult was that the AC was in the bedroom and didn’t extend out to the living space so our kids were hot when they slept on the pullout couch. Otherwise, couldn’t have asked for friendlier staff or a better stay! "
A verified traveler stayed at Drury Inn & Suites Sikeston, MO
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An Attraction
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Southeast Missouri State University
- Hotels near Isle Casino Cape Girardeau
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- Hotels near Cape Splash Family Aquatic Center
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