$251 Cheap American Airlines flights from Aspen to Knoxville (ASE to TYS)

Find The Best Day To Fly from Aspen to Knoxville

Amazing American Airlines ASE to TYS Flight Deals

The cheapest flights to McGhee Tyson found within the past 7 days were $392 round trip and $251 one way. Prices and availability subject to change. Additional terms may apply.

Fri, Sep 12 - Mon, Sep 15
ASE
Aspen
TYS
Knoxville
$392 Roundtrip, found 2 days ago
$392
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Sep 12 from Aspen to Knoxville, returning Mon, Sep 15, priced at $392 found 2 days ago
Fri, Sep 12 - Mon, Sep 15
ASE
Aspen
TYS
Knoxville
$472 Roundtrip, found 2 days ago
$472
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Sep 12 from Aspen to Knoxville, returning Mon, Sep 15, priced at $472 found 2 days ago
Fri, Sep 12 - Mon, Sep 15
ASE
Aspen
TYS
Knoxville
$483 Roundtrip, found 2 days ago
$483
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Sep 12 from Aspen to Knoxville, returning Mon, Sep 15, priced at $483 found 2 days ago
Fri, Sep 12 - Mon, Sep 15
ASE
Aspen
TYS
Knoxville
$504 Roundtrip, found 2 days ago
$504
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Sep 12 from Aspen to Knoxville, returning Mon, Sep 15, priced at $504 found 2 days ago
Fri, Sep 12 - Mon, Sep 15
ASE
Aspen
TYS
Knoxville
$511 Roundtrip, found 2 days ago
$511
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Sep 12 from Aspen to Knoxville, returning Mon, Sep 15, priced at $511 found 2 days ago
Fri, Sep 12 - Mon, Sep 15
ASE
Aspen
TYS
Knoxville
$511 Roundtrip, found 2 days ago
$511
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Sep 12 from Aspen to Knoxville, returning Mon, Sep 15, priced at $511 found 2 days ago

TYS From ASE Economy Coach Packages on Similar Airlines

Price found within the past 48 hours. Click for updated prices.
Great Smokies Inn Cherokee

Great Smokies Inn Cherokee

2.5 out of 5
per person
Aug 4 - Aug 8
found 1 day ago
Roundtrip flight included
Denver (DEN) to Knoxville (TYS)
Balsam Mountain Inn

Balsam Mountain Inn

2 out of 5
per person
Aug 4 - Aug 8
found 1 day ago
Roundtrip flight included
Denver (DEN) to Knoxville (TYS)
Newfound Lodge on the river

Newfound Lodge on the river

2 out of 5
per person
Aug 4 - Aug 8
found 1 day ago
Roundtrip flight included
Denver (DEN) to Knoxville (TYS)
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American Airlines Airports
Hop on a(n) American Airlines flight today by flying to many destinations out of these domestic and international airports:
Airport code
Country
Airport name
Number of flights
DFWUSADallas-Fort Worth Intl.599
CLTUSACharlotte-Douglas Intl.536
ORDUSAO'Hare Intl.317
PHLUSAPhiladelphia Intl.247
MIAUSAMiami Intl.193
DCAUSARonald Reagan Washington National152
PHXUSASky Harbor Intl.141
LAXUSALos Angeles Intl.81
LGAUSALaGuardia72
BOSUSALogan Intl.57

Travelers ❤️ these 🏨 after their flight to Knoxville

Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,011 reviews)
"Great location to the airport and fantastic staff!"

Reviewed on Jul 15, 2025

Hilton Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road, Alcoa, TN
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free ...
8.6/10 Excellent! (1,477 reviews)
"Exactly what we needed for our business trip. Highly recommended ⭐️⭐️⭐️⭐️⭐️"

Reviewed on Jul 14, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
8.4/10 Very Good! (1,014 reviews)
"Very clean"

Reviewed on Jul 16, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.