$302 Cheap American Airlines flights from Knoxville to Santo Domingo (TYS to SDQ)

Find The Best Day To Fly from Knoxville to Santo Domingo

Amazing American Airlines TYS to SDQ Flight Deals

The cheapest flights to Las Americas Intl. found within the past 7 days were $541 round trip and $302 one way. Prices and availability subject to change. Additional terms may apply.

Sun, Jul 20 - Sat, Jul 26
TYS
Knoxville
SDQ
Santo Domingo
$541 Roundtrip, found 12 hours ago
$541
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sun, Jul 20 from Knoxville to Santo Domingo, returning Sat, Jul 26, priced at $541 found 12 hours ago
Sun, Jul 20 - Sat, Jul 26
TYS
Knoxville
SDQ
Santo Domingo
$551 Roundtrip, found 12 hours ago
$551
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sun, Jul 20 from Knoxville to Santo Domingo, returning Sat, Jul 26, priced at $551 found 12 hours ago
Sun, Jul 20 - Sat, Jul 26
TYS
Knoxville
SDQ
Santo Domingo
$559 Roundtrip, found 12 hours ago
$559
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sun, Jul 20 from Knoxville to Santo Domingo, returning Sat, Jul 26, priced at $559 found 12 hours ago
Sun, Jul 20 - Sat, Jul 26
TYS
Knoxville
SDQ
Santo Domingo
$570 Roundtrip, found 12 hours ago
$570
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sun, Jul 20 from Knoxville to Santo Domingo, returning Sat, Jul 26, priced at $570 found 12 hours ago
Sun, Jul 20 - Thu, Jul 24
TYS
Knoxville
SDQ
Santo Domingo
$630 Roundtrip, found 11 hours ago
$630
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sun, Jul 20 from Knoxville to Santo Domingo, returning Thu, Jul 24, priced at $630 found 11 hours ago
Sun, Jul 20 - Wed, Jul 23
TYS
Knoxville
SDQ
Santo Domingo
$634 Roundtrip, found 11 hours ago
$634
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sun, Jul 20 from Knoxville to Santo Domingo, returning Wed, Jul 23, priced at $634 found 11 hours ago

SDQ From TYS Economy Coach Packages on Similar Airlines

Price found within the past 48 hours. Click for updated prices.
Bahia Principe Grand La Romana - All Inclusive

Bahia Principe Grand La Romana - All Inclusive

4.5 out of 5
Save 100% on your flight
per person
Aug 30 - Sep 6
found 21 hours ago
Roundtrip non-stop flight included
Knoxville (TYS) to Santo Domingo (SDQ)
Coral Costa Caribe Beach Resort - All Inclusive

Coral Costa Caribe Beach Resort - All Inclusive

4 out of 5
Save 100% on your flight
per person
Jul 31 - Aug 5
found 1 day ago
Roundtrip non-stop flight included
Knoxville (TYS) to Santo Domingo (SDQ)
Bahia Principe Luxury Bouganville - Adults Only - All Inclusive

Bahia Principe Luxury Bouganville - Adults Only - All Inclusive

4.5 out of 5
Save 100% on your flight
per person
Aug 30 - Sep 6
found 21 hours ago
Roundtrip non-stop flight included
Knoxville (TYS) to Santo Domingo (SDQ)
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American Airlines Airports
Hop on a(n) American Airlines flight today by flying to many destinations out of these domestic and international airports:
Airport code
Country
Airport name
Number of flights
DFWUSADallas-Fort Worth Intl.599
CLTUSACharlotte-Douglas Intl.536
ORDUSAO'Hare Intl.317
PHLUSAPhiladelphia Intl.247
MIAUSAMiami Intl.193
DCAUSARonald Reagan Washington National152
PHXUSASky Harbor Intl.141
LAXUSALos Angeles Intl.81
LGAUSALaGuardia72
BOSUSALogan Intl.57

Travelers ❤️ these 🏨 after their flight to Santo Domingo

whala! boca chica - All inclusive

whala! boca chica - All inclusive

3 out of 5
Avenida Abraham Núñez, Boca Chica, Santo Domingo
This all-inclusive property includes 3 restaurants, an outdoor pool, and a gym. Unwind with a drink at the bar/lounge and enjoy perks like free buffet breakfast ...
7/10 Good! (2,021 reviews)
"Didn't supply clean towels second day.Had 2 ask 4 more t p."

Reviewed on Jul 15, 2025

whala! boca chica - All inclusive
Hampton by Hilton Santo Domingo Airport

Hampton by Hilton Santo Domingo Airport

3.5 out of 5
Avenida Las Américas, Km27, Boca Chica
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9/10 Wonderful! (1,001 reviews)
"Great stay"

Reviewed on Jul 2, 2025

Hampton by Hilton Santo Domingo Airport
Four Points by Sheraton Santo Domingo

Four Points by Sheraton Santo Domingo

4 out of 5
KM 22 Autopista Las Americas, next to Las Americas Free Zn, Boca Chica, Santo Domingo
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8/10 Very Good! (69 reviews)
"Me gustó"

Reviewed on Jul 7, 2025

Four Points by Sheraton Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.