
$212 Cheap American Airlines flights from Detroit to Des Moines (DTW to DSM)
Find The Best Day To Fly from Detroit to Des Moines
Amazing American Airlines DTW to DSM Flight Deals
The cheapest flights to Des Moines Intl. found within the past 7 days were $324 round trip and $212 one way. Prices and availability subject to change. Additional terms may apply.
DSM From DTW Economy Coach Packages on Similar Airlines



Frequently asked questions
Discover our best American Airlines flight from Detroit DTW to Des Moines DSM
To find the best deals on flights to Detroit from Des Moines with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Detroit DTW to Des Moines DSM with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $324 to $324, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Detroit DTW to Des Moines DSM
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Detroit to Des Moines costs from $212. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Des Moines DSM from Detroit DTW with American Airlines
To find a cheap American Airlines flight from Detroit DTW to Des Moines DSM, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Detroit DTW to Des Moines DSM
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as August, or if you book a flight with a stopover.
Find nonstop flights from Detroit DTW to Des Moines DSM with American Airlines
If you’re keen to be on Des Moines soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Detroit DTW to Des Moines DSM
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Des Moines DSM from Detroit DTW with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
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Popular American Airlines Flight Routes from DTW
Top American Airlines Flight Routes from DSM
Top Flights for American Airlines originating from DTW
Domestic
- Orlando to San Juan (MCO - SJU)
- Philadelphia to Orlando (PHL - MCO)
- Boston to San Juan (BOS - SJU)
- New York to Montego Bay (JFK - MBJ)
- New York to San Juan (JFK - SJU)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- New York to Orlando (JFK - MCO)
- Atlanta to New York (ATL - LGA)
- New York to Orlando (JFK - MCO)
- Atlanta to New York (ATL - LGA)
International
- San Juan to Orlando (SJU - MCO)
- New York to Orlando (JFK - MCO)
- Philadelphia to San Juan (PHL - SJU)
- New York to Santo Domingo (JFK - SDQ)
- Philadelphia to San Juan (PHL - SJU)
- Los Angeles to San Salvador (LAX - SAL)
- Los Angeles to San Salvador (LAX - SAL)
- San Juan to Orlando (SJU - MCO)
- New York to Santiago (JFK - STI)
- New York to San Juan (JFK - SJU)
Most Popular
- Grand Rapids to Fort Myers (GRR - RSW)
- Denver to Des Moines (DEN - DSM)
- Grand Rapids to Los Angeles (GRR - LAX)
- Cedar Rapids to Orlando (CID - MCO)
- Des Moines to Seattle (DSM - SEA)
- Cedar Rapids to Dallas (CID - DFW)
- Flint to Orlando (FNT - MCO)
- Grand Rapids to Dallas (GRR - DFW)
- Grand Rapids to Tampa (GRR - TPA)
- Des Moines to Orlando (DSM - MCO)
- Grand Rapids to Phoenix (GRR - PHX)
- Des Moines to Phoenix (DSM - PHX)
- Grand Rapids to Las Vegas (GRR - LAS)
- Delta Grand Rapids (GRR) to Honolulu (HNL) flights
- Grand Rapids to Portland (GRR - PDX)
- Des Moines to Chicago (DSM - ORD)
- Chicago to Des Moines (ORD - DSM)
- Delta Des Moines (DSM) to Las Vegas (LAS) flights
- Grand Rapids to New Orleans (GRR - MSY)
- Phoenix to Des Moines (PHX - DSM)
- Cedar Rapids to Denver (CID - DEN)
- Des Moines to Denver (DSM - DEN)
- Grand Rapids to Orlando (GRR - MCO)
- American Airlines Traverse City (TVC) to Denver (DEN) flights
- United Denver (DEN) to Grand Rapids (GRR) flights
- Des Moines to Dallas (DSM - DFW)
- American Airlines Cedar Rapids (CID) to Phoenix (PHX) flights
- Grand Rapids to Denver (GRR - DEN)
- Grand Rapids to Miami (GRR - MIA)
- Cedar Rapids to Seattle (CID - SEA)