$349 Cheap American Airlines flights from Salisbury to Knoxville (SBY to TYS)

Find The Best Day To Fly from Salisbury to Knoxville

Amazing American Airlines SBY to TYS Flight Deals

The cheapest flights to McGhee Tyson found within the past 7 days were $462 round trip and $349 one way. Prices and availability subject to change. Additional terms may apply.

Sun, Aug 31 - Sat, Sep 6
SBY
Salisbury
TYS
Knoxville
$462 Roundtrip, found 5 days ago
$462
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sun, Aug 31 from Salisbury to Knoxville, returning Sat, Sep 6, priced at $462 found 5 days ago
Sun, Aug 31 - Sun, Sep 7
SBY
Salisbury
TYS
Knoxville
$466 Roundtrip, found 5 days ago
$466
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sun, Aug 31 from Salisbury to Knoxville, returning Sun, Sep 7, priced at $466 found 5 days ago
Wed, Aug 27 - Sat, Sep 6
SBY
Salisbury
TYS
Knoxville
$470 Roundtrip, found 5 days ago
$470
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Aug 27 from Salisbury to Knoxville, returning Sat, Sep 6, priced at $470 found 5 days ago
Wed, Aug 27 - Thu, Sep 4
SBY
Salisbury
TYS
Knoxville
$474 Roundtrip, found 5 days ago
$474
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Aug 27 from Salisbury to Knoxville, returning Thu, Sep 4, priced at $474 found 5 days ago
Fri, Aug 29 - Thu, Sep 4
SBY
Salisbury
TYS
Knoxville
$478 Roundtrip, found 5 days ago
$478
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Aug 29 from Salisbury to Knoxville, returning Thu, Sep 4, priced at $478 found 5 days ago
Tue, Jul 22 - Wed, Jul 30
SBY
Salisbury
TYS
Knoxville
$481 Roundtrip, found 11 hours ago
$481
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Tue, Jul 22 from Salisbury to Knoxville, returning Wed, Jul 30, priced at $481 found 11 hours ago
American Airlines Airports
Hop on a(n) American Airlines flight today by flying to many destinations out of these domestic and international airports:
Airport code
Country
Airport name
Number of flights
DFWUSADallas-Fort Worth Intl.599
CLTUSACharlotte-Douglas Intl.536
ORDUSAO'Hare Intl.317
PHLUSAPhiladelphia Intl.247
MIAUSAMiami Intl.193
DCAUSARonald Reagan Washington National152
PHXUSASky Harbor Intl.141
LAXUSALos Angeles Intl.81
LGAUSALaGuardia72
BOSUSALogan Intl.57

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Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,011 reviews)
"Great location to the airport and fantastic staff!"

Reviewed on Jul 15, 2025

Hilton Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road, Alcoa, TN
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free ...
8.6/10 Excellent! (1,477 reviews)
"Exactly what we needed for our business trip. Highly recommended ⭐️⭐️⭐️⭐️⭐️"

Reviewed on Jul 14, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
8.4/10 Very Good! (1,014 reviews)
"Very clean"

Reviewed on Jul 16, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.