
$173 Cheap American Airlines flights from Charlotte to San Francisco (CLT to SFO)
Find The Best Day To Fly from Charlotte to San Francisco
Amazing American Airlines CLT to SFO Flight Deals
The cheapest flights to San Francisco Intl. found within the past 7 days were $330 round trip and $173 one way. Prices and availability subject to change. Additional terms may apply.
CLT
Charlotte
SFO
San Francisco
$330 Roundtrip, found 7 hours ago
$330
Roundtrip
found 7 hours ago
CLT
Charlotte
SFO
San Francisco
$334 Roundtrip, found 7 hours ago
$334
Roundtrip
found 7 hours ago
CLT
Charlotte
SFO
San Francisco
$340 Roundtrip, found 15 hours ago
$340
Roundtrip
found 15 hours ago
CLT
Charlotte
SFO
San Francisco
$344 Roundtrip, found 1 day ago
$344
Roundtrip
found 1 day ago
CLT
Charlotte
SFO
San Francisco
$453 Roundtrip, found 7 hours ago
$453
Roundtrip
found 7 hours ago
SFO From CLT Economy Coach Packages on Similar Airlines
Price found within the past 48 hours. Click for updated prices.



Don't see what you're looking for?
See all available trips from Charlotte-Douglas Intl. to San Francisco Intl.
View all tripsFrequently asked questions
Travelers ❤️ these 🏨 after their flight to San Francisco

Grand Hyatt at SFO
55 S McDonnell Rd, San Francisco, CA
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet ...
9.6/10 Exceptional! (1,365 reviews)
"Great"
Reviewed on Jul 15, 2025

SFO El Rancho Inn SureStay Collection by Best Western
1100 El Camino Real, Millbrae, CA
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 2 conference rooms, along with free WiFi in public ...
8.2/10 Very Good! (2,840 reviews)
"We only spent 2days and 1 nite but it was great. It’s closer to where we were going. I wouldn’t mind staying at this place again if ever we needed a place to stay. Staff were very friendly and helpful especially Ms Angie at the front desk."
Reviewed on Jul 16, 2025

Crowne Plaza San Francisco Airport by IHG
1177 Airport Blvd, Burlingame, CA
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport shuttle. ...
7.6/10 Good! (1,902 reviews)
"The food smelled delicious and awesome customer service"
Reviewed on Jul 16, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular American Airlines Flight Routes from CLT
- American Airlines CLT to LGA
- American Airlines CLT to CUN
- American Airlines CLT to EWR
- American Airlines CLT to PUJ
- American Airlines CLT to SLC
- American Airlines CLT to LAS
- American Airlines CLT to SJU
- American Airlines CLT to SFO
- American Airlines CLT to SAL
- American Airlines CLT to MIA
- American Airlines CLT to DEN
Top Flights for American Airlines originating from CLT
Domestic
- Philadelphia to San Juan (PHL - SJU)
- New York to Montego Bay (JFK - MBJ)
- Dallas to Las Vegas (DFW - LAS)
- Chicago to Las Vegas (ORD - LAS)
- New York to San Juan (JFK - SJU)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- New York to Orlando (LGA - MCO)
- Los Angeles to Honolulu (LAX - HNL)
- Los Angeles to San Salvador (LAX - SAL)
International
- Philadelphia to Orlando (PHL - MCO)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- Philadelphia to San Juan (PHL - SJU)
- New York to Santiago (JFK - STI)
- Los Angeles to Honolulu (LAX - HNL)
- New York to San Juan (JFK - SJU)
- New York to Las Vegas (JFK - LAS)
- New York to San Juan (JFK - SJU)
- Philadelphia to San Juan (PHL - SJU)
- Chicago to Las Vegas (ORD - LAS)
Most Popular
Flights
- Los Angeles to Chicago (LAX - ORD)
- Los Angeles to London (LAX - LHR)
- Los Angeles to Atlanta (LAX - ATL)
- Portland to Los Angeles (PDX - LAX)
- Houston to Los Angeles (IAH - LAX)
- Los Angeles to Cancun (LAX - CUN)
- Raleigh to Orlando (RDU - MCO)
- Los Angeles to Paris (LAX - CDG)
- Los Angeles to Orlando (LAX - MCO)
- Boston to Los Angeles (BOS - LAX)
- Los Angeles to Miami (LAX - MIA)
- Los Angeles to Honolulu (LAX - HNL)
- Los Angeles to Dallas (LAX - DFW)
- Los Angeles to New York (LAX - JFK)
- San Francisco to Los Angeles (SFO - LAX)
- Orlando to Los Angeles (MCO - LAX)
- New York to Los Angeles (JFK - LAX)
- Los Angeles to Mexico City (LAX - MEX)
- Atlanta to Los Angeles (ATL - LAX)
- Los Angeles to Portland (LAX - PDX)
- Phoenix to Los Angeles (PHX - LAX)
- Salt Lake City to Los Angeles (SLC - LAX)
- Los Angeles to Boston (LAX - BOS)
- Charlotte to Orlando (CLT - MCO)
- Chicago to Los Angeles (ORD - LAX)
- Los Angeles to Washington (LAX - DCA)
- Philadelphia to Los Angeles (PHL - LAX)
- Los Angeles to Seattle (LAX - SEA)
- Los Angeles to San Francisco (LAX - SFO)
- Dallas to Los Angeles (DFW - LAX)