Cheap Flights to Southern Illinois from $45

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How Much Does it Cost To Fly To Southern Illinois?

The cheapest prices found with in the last 7 days for return flights were $55 and $45 for one-way flights to Southern Illinois for the period specified. Prices and availability are subject to change. Additional terms apply

Fri, Nov 6 - Mon, Nov 16
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$55 Roundtrip, found 3 days ago
$55
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, Nov 6 from Denver Intl. to Lambert-St. Louis Intl., returning Mon, Nov 16, priced at $55 found 3 days ago
Wed, Oct 14 - Thu, Oct 15
SEA
Seattle - Tacoma Intl.
STL
Lambert-St. Louis Intl.
$222 Roundtrip, found 5 hours ago
$222
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Wed, Oct 14 from Seattle - Tacoma Intl. to Lambert-St. Louis Intl., returning Thu, Oct 15, priced at $222 found 5 hours ago
OriginDestinationTravel DatesFlights From*
DFWSt. LouisOctober 29 to November 2$110
PGDMascoutahOctober 22 to October 25$191
DFWScott CityNovember 5 to November 8$238
ORFSt. LouisOctober 23 to October 26$272
DFWWest PaducahOctober 29 to October 31$328
RSWWest PaducahOctober 22 to October 25$328
PVDSt. LouisOctober 22 to October 25$393
RSWSt. LouisOctober 16 to October 18$428
AUSEvansvilleOctober 14 to October 19$447
RSWEvansvilleOctober 22 to October 25$463
BNAScott CityOctober 2 to October 5$473
DALEvansvilleOctober 15 to October 20$512
ORFMarionOctober 1 to October 8$633
ORFEvansvilleOctober 1 to October 2$776
RSWScott CitySeptember 25 to September 27$829
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
BNASt. LouisSeptember 18 to September 20$283
DFWSt. LouisSeptember 20 to September 27$344
AUSSt. LouisSeptember 20 to October 7$390
RSWSt. LouisSeptember 18 to September 25$487
CLTSt. LouisSeptember 19 to September 21$516
DCASt. LouisSeptember 18 to September 21$570
DALEvansvilleSeptember 18 to September 20$986
CLESt. LouisSeptember 19 to September 21$1,016
CLTScott CitySeptember 18 to September 20$1,456
*Prices include taxes and fees

Southern Illinois Flight Information

Traveling to
Southern Illinois
Lowest Price
$55
Number of Airlines Serving
Airlines Serving
Frontier Airlines, Southwest Airlines, American Airlines
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Southern Illinois Accommodation Deals

Motel 6 Caseyville, IL - Caseyville Il

Motel 6 Caseyville, IL - Caseyville Il

2 out of 5
2431 Old Country Inn Dr Caseyville IL
$62 nightly
The price is $70 total per night from Oct 14 to Oct 15
$70 total
Oct 14 - Oct 15
Total with taxes and fees
Stay at this motel in Caseyville. Enjoy free parking, an outdoor pool, and a 24-hour front desk. Popular attractions Cahokia Mounds State Historic Site and Frank ...
6.4/10 (1,002 reviews)
"Average"

Reviewed on Sep 12, 2026

Opens in a new windowMotel 6 Caseyville, IL - Caseyville Il
Days Inn by Wyndham Charleston

Days Inn by Wyndham Charleston

2 out of 5
810 West Lincoln Avenue Charleston IL
$82 nightly
The price is $91 total per night from Sep 20 to Sep 21
$91 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this hotel in Charleston. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (810 reviews)
"The bed we had was broke and if you moved you could hear the boards in the springs banging together"

Reviewed on Aug 17, 2026

Opens in a new windowDays Inn by Wyndham Charleston
Super 8 by Wyndham Marion

Super 8 by Wyndham Marion

2 out of 5
2601 Vernell Rd Marion IL
$74 nightly
The price is $89 total per night from Sep 20 to Sep 21
$89 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly motel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (1,001 reviews)
"No shampoo in room."

Reviewed on Sep 11, 2026

Opens in a new windowSuper 8 by Wyndham Marion
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Americas Best Value Inn West Frankfort

Americas Best Value Inn West Frankfort

2.5 out of 5
1001 Factory Outlet Blvd West Frankfort IL
$72 nightly
The price is $80 total per night from Sep 17 to Sep 18
$80 total
Sep 17 - Sep 18
Total with taxes and fees
Stay at this motel in West Frankfort. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (533 reviews)
"STAFF WAS PHENOMIAL THIS WILL BE MY #1 CHICE OF STAY FOR THE NEXT 4 YEARS"

Reviewed on Sep 13, 2026

Opens in a new windowAmericas Best Value Inn West Frankfort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Southern Illinois

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area

2 out of 5
910 Edwardsville Rd Troy IL
$68 nightly
The price is $75 total per night from Sep 21 to Sep 22
$75 total
Sep 21 - Sep 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Troy. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,003 reviews)
"Very nice and quiet place"

Reviewed on Sep 12, 2026

Opens in a new windowSuper 8 by Wyndham Troy IL/St. Louis Area
Rodeway Inn Effingham North

Rodeway Inn Effingham North

2 out of 5
1400 Thelma Keller Ave Effingham IL
$68 nightly
The price is $76 total per night from Sep 28 to Sep 29
$76 total
Sep 28 - Sep 29
Total with taxes and fees
Stay at this motel in Effingham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,000 reviews)
"The toilet in my room did not work correctly. I only stayed for a night but the front desk offered to change my room if I felt the need. Overall the price reflects the quality. Could’ve been worse and could have been better."

Reviewed on Aug 30, 2026

Opens in a new windowRodeway Inn Effingham North
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

3.5 out of 5
100 E Front St Metropolis IL
$115 nightly
The price is $128 total per night from Sep 20 to Sep 21
$128 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this hotel in Metropolis. Enjoy free parking, 2 restaurants, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.2/10 Very Good! (1,002 reviews)
"I enjoyed my stay at Harrahs. The hotel was nice and clean. The staff was friendly and helpful. I ordered room service food from the grill which arrived quickly and tasted fresh. The only thing I was wondering was why The Bridges didn't have room service. I did go to Bridges for breakfast and it ..."

Reviewed on Sep 12, 2026

Opens in a new windowHarrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
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Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL

2.5 out of 5
401 S 44th St Mount Vernon IL
$73 nightly
The price is $83 total per night from Sep 15 to Sep 16
$83 total
Sep 15 - Sep 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Opens in a new windowSuper 8 by Wyndham Mt. Vernon IL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Southern Illinois

Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

2.5 out of 5
1306 Halfway Road Marion IL
$90 nightly
The price is $108 total per night from Oct 4 to Oct 5
$108 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,003 reviews)
"Clean, nice location"

Reviewed on Sep 14, 2026

Opens in a new windowCountry Inn & Suites by Radisson, Marion, IL
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
145 North 44th Street  Mount Vernon IL
$111 nightly
The price is $125 total per night from Sep 20 to Sep 21
$125 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.8/10 Exceptional! (1,812 reviews)
"We were meeting up with family for the weekend. Hotel staff went out of their way to keep us together. Rooms were clean and bed comfortable."

Reviewed on Sep 13, 2026

Opens in a new windowDrury Plaza Hotel Mt. Vernon
Comfort Inn & Suites O'Fallon - St. Louis Area

Comfort Inn & Suites O'Fallon - St. Louis Area

2 out of 5
116 Regency Park O'Fallon IL
$79 nightly
The price is $91 total per night from Oct 13 to Oct 14
$91 total
Oct 13 - Oct 14
Total with taxes and fees
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Opens in a new windowComfort Inn & Suites O'Fallon - St. Louis Area
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Holiday Inn Express & Suites Effingham by IHG

Holiday Inn Express & Suites Effingham by IHG

2.5 out of 5
1604 West Fayette Avenue Effingham IL
$125 nightly
The price is $140 total per night from Sep 20 to Sep 21
$140 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Opens in a new windowHoliday Inn Express & Suites Effingham by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Compact SUV

  • 5 people
  • Unlimited mileage
Saint Louis, Missouri, USA

$59

$179 total
found 5 days ago
Compact SUV undefined

Mini Van

  • 7 people
  • Unlimited mileage
Saint Louis, Missouri, USA

$61

$186 total
found 5 days ago
Mini Van undefined

Economy

  • 4 people
  • Unlimited mileage
Saint Louis, Missouri, USA

$64

$183 total
found 5 days ago
Economy undefined

Midsize

  • 5 people
  • Unlimited mileage
Saint Louis, Missouri, USA

$66

$189 total
found 5 days ago
Midsize undefined
Lowest prices found within the past 5 days. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much is the cheapest flight to Southern Illinois?
A roundtrip flight to Southern Illinois cost as little as $55 in the last seven days. Once you've decided on your travel dates, we'll help you grab a good deal. This price was available on Travelocity for flights to Southern Illinois departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly to Southern Illinois?
According to Travelocity's direct return flight demand between January and December last year, November is the cheapest period to jet off to Southern Illinois. Look for flights across this month and snag a terrific deal today.
How can I check my flight status to Southern Illinois?
There are a few simple ways to check your fight status. You can find all the necessary details in our "Trips" portal, which is located at the top of our homepage. Log in or create an account — you'll then be able to browse and amend your bookings whenever you need to. If you're already traveling, the Travelocity app can also help you check the status of your flight to Southern Illinois, as well as share details with any members of your family flying with you.
How do I find the best deals on flights to Southern Illinois?
It's good to book ahead of time, and if you can, avoid traveling during peak periods. Another great way to save is by clicking the "Flexible dates" box at the top of the page after searching for your flights. It's an easy way to compare prices for surrounding days. In the last seven days, the best price for a roundtrip flight to Southern Illinois was $55. This price was available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Why should I book my flight to Southern Illinois with Travelocity?
An exciting vacation is just a click away when you book your trip with Travelocity. With a wide selection of choices and great deals on cheap family flights, rental cars and more, we make it simple to locate the best prices for you. You can also take advantage of our 24/7 customer support and free cancellations on most hotels during your trip. Wander with us and secure your cheap flights to Southern Illinois today.
How much is a flight to Southern Illinois on average?
Based on prices found over the last seven days, roundtrip flights to Southern Illinois cost between $55 and $1,456. When you're ready to hop on a plane, Travelocity will help you find a fare that won't blow your budget. These prices were available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What can I expect on a flight to Southern Illinois?
If you have a long-haul flight to Southern Illinois, you can usually expect drinks, meals and entertainment on board. Airlines like to make longer flights as pleasant as possible. Shorter journeys — as well as flights offered by budget airlines — may not have as many inclusions. If you're chasing cheap flights for family vacations with a low-cost carrier, you'll usually have to pay extra for snacks, drinks and entertainment.

Plane Tickets To Southern Illinois

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Southern Illinois. Browse through our inventory to explore a wide range of cheap flights to Southern Illinois to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Southern Illinois as you anxiously await to exit the plane and explore what Southern Illinois has to offer. Considering all the amazing local food and culture in Southern Illinois, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Southern Illinois to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Southern Illinois without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Southern Illinois with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Southern Illinois today!

Explore More Ways to Travel with Travelocity

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.