Explore 54 Luxury Hotels in Southern Illinois
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Best Luxury Hotels in Southern Illinois
Quality Inn Effingham North
1304 W Evergreen Drive Effingham IL
Fully refundable
$85 nightly
The price is $94 total per night from Oct 25 to Oct 26
$94 total
Oct 25 - Oct 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the sauna and free perks like buffet breakfast and free self parking. Free WiFi in public areas, a library, ...
8.4/10 Very Good! (1,007 reviews)
"the lady who checked me in was really nice and the room was mostly clean but it had an odd smell. overall i would probably stay again"
Reviewed on Sep 28, 2026
Super 8 by Wyndham Troy IL/St. Louis Area
910 Edwardsville Rd Troy IL
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Oct 5 to Oct 6
$71 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
8.2/10 Very Good! (1,007 reviews)
"Walls had obvious fist marks indented in them, even though the beds were made and towles desplayed nicely they both had obvious blood spots on them, bed could easily be pushed off the frame, dust/dirt in every corner of the room, shoer curtain had mold spots. Questionable if the room had even been ..."
Reviewed on Sep 27, 2026
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
100 E Front St Metropolis IL
$117 nightly
The price is $130 total per night from Oct 28 to Oct 29
$130 total
Oct 28 - Oct 29
Total with taxes and fees
This hotel features a casino and 2 restaurants. Relax with a drink at the bar/lounge and enjoy perks like free self parking and free WiFi. A snack bar/deli, ...
8.2/10 Very Good! (1,006 reviews)
"not full and quiet for a casino environment."
Reviewed on Sep 26, 2026
Holiday Inn Express & Suites Mattoon by IHG
121 Swords Dr Mattoon IL
Fully refundable
$98 nightly
The price is $110 total per night from Oct 29 to Oct 30
$110 total
Oct 29 - Oct 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 24-hour ...
8.2/10 Very Good! (836 reviews)
"This property is nice and quiet and not too close to the road for road noise. The check in experience was pretty good. The young lady working the desk was hospitable and cordial. The room was comfortable and spacious. Breakfast was great and the options were very nice. We encountered a few issues ..."
Reviewed on Sep 28, 2026
Rodeway Inn Effingham North
1400 Thelma Keller Ave Effingham IL
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $77 total per night from Sep 30 to Oct 1
$77 total
Sep 30 - Oct 1
Total with taxes and fees
Free self parking is available and the motel's front desk is staffed around-the-clock. WiFi in public areas is free. A picnic area is also provided.
7.4/10 Good! (1,000 reviews)
"The toilet in my room did not work correctly. I only stayed for a night but the front desk offered to change my room if I felt the need. Overall the price reflects the quality. Could’ve been worse and could have been better."
Reviewed on Aug 30, 2026
Days Inn by Wyndham Effingham
1602 Damron Court Effingham IL
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Oct 26 to Oct 27
$71 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features a gym and a sauna. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate ...
6.2/10 (1,000 reviews)
"clean room, weird parking lot more gravel than pavement. It was a very hot day and the AC was really struggling when I got there. didn't cool off real good until middle of the night"
Reviewed on Sep 11, 2026
Super 8 by Wyndham Mt. Vernon IL
401 S 44th St Mount Vernon IL
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $83 total per night from Sep 30 to Oct 1
$83 total
Sep 30 - Oct 1
Total with taxes and fees
This hotel features free WiFi in public areas, free newspapers, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...
Super 8 by Wyndham Carbondale
1180 E Main St Carbondale IL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $75 total per night from Sep 30 to Oct 1
$75 total
Sep 30 - Oct 1
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Multilingual staff at the 24-hour front desk ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southern Illinois Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southern Illinois luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Southern Illinois to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Southern Illinois will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southern Illinois, and plan your next opulent escape.
Southern Illinois hotels essential information
Accommodation | 1,213 hotels |
|---|---|
Lowest Price | $71 |
Highest Price | $130 |
Popular hotels | Super 8 by Wyndham Troy IL/St. Louis Area, Rodeway Inn Effingham North, Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination, Super 8 by Wyndham Mt. Vernon IL, Days Inn by Wyndham Effingham, Super 8 by Wyndham Carbondale, Holiday Inn Express & Suites Mattoon by IHG, Quality Inn Effingham North |
Popular Luxury Stays in Southern Illinois
Recent Southern Illinois Hotel Reviews By Fellow Wanderers
Ramada by Wyndham Effingham
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"It is a modest hotel with helpful staff, easily accessible handicapped parking, and surprisingly good scrambled eggs :)"
A verified traveler stayed at Ramada by Wyndham Effingham