Explore 54 Luxury Hotels in Southern Illinois

Name: Days Inn by Wyndham Effingham
Price range: $61 total
Rating: 6.2

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Best Luxury Hotels in Southern Illinois

Quality Inn Effingham North

1304 W Evergreen Drive Effingham IL

Fully refundable

$81 nightly

$89 total

Jul 5 - Jul 6

Total with taxes and fees

This hotel features an indoor pool and a gym. Enjoy the sauna and free perks like buffet breakfast and free self parking. Free WiFi in public areas, a library, ...

8.4/10 Very Good! (1,002 reviews)

"The staff was very friendly. The facilities looked clean. The room was clean. Breakfast was very good. I felt safe at this hotel."

Reviewed on Jun 27, 2026

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

100 E Front St Metropolis IL

$122 nightly

$135 total

Jul 28 - Jul 29

Total with taxes and fees

This hotel features a casino and 2 restaurants. Relax with a drink at the bar/lounge and enjoy perks like free self parking and free WiFi. A snack bar/deli, ...

8.2/10 Very Good! (1,002 reviews)

"The restaurant has excellent food and prices are in line with the other restaurants. The only downside was no workout room and no pool. Mine was a family weekend for an event being held. Other than that everything from the staff, the room, the eatery, the location was very good."

Reviewed on Jun 28, 2026

Holiday Inn Express & Suites Mattoon by IHG

121 Swords Dr Mattoon IL

Fully refundable

$101 nightly

$113 total

Jul 30 - Jul 31

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 24-hour ...

8.2/10 Very Good! (807 reviews)

"The stay was fine but it's pretty bad when there is no real cable tv. The Roku was a pain too figure out and was told by the staff that they had no idea how to get it to work either. lol Spending over $200 a night shouldn't require 30 minutes to get the tv to work and the only free viewing requires ..."

Reviewed on Jun 28, 2026

Super 8 by Wyndham Troy IL/St. Louis Area

910 Edwardsville Rd Troy IL

Fully refundableReserve now, pay when you stay

$72 nightly

$80 total

Jun 30 - Jul 1

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...

8/10 Very Good! (1,007 reviews)

"I like being able to walk to get dinner."

Reviewed on Jun 28, 2026

Super 8 by Wyndham Mt. Vernon IL

401 S 44th St Mount Vernon IL

Fully refundableReserve now, pay when you stay

$79 nightly

$90 total

Jul 7 - Jul 8

Total with taxes and fees

This hotel features free WiFi in public areas, free newspapers, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...

7.8/10 Good! (1,003 reviews)

"Clean room. Friendly staff. Easy parking. No elevator."

Reviewed on Jun 27, 2026

Rodeway Inn Effingham North

1400 Thelma Keller Ave Effingham IL

Fully refundableReserve now, pay when you stay

$75 nightly

$83 total

Jun 30 - Jul 1

Total with taxes and fees

Free self parking is available and the motel's front desk is staffed around-the-clock. WiFi in public areas is free. A picnic area is also provided.

7.6/10 Good! (1,001 reviews)

"Clean room but needs renovations. Cold AC."

Reviewed on Jun 28, 2026

Super 8 by Wyndham Carbondale

1180 E Main St Carbondale IL

Fully refundableReserve now, pay when you stay

$68 nightly

$78 total

Jun 30 - Jul 1

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Multilingual staff at the 24-hour front desk ...

7.4/10 Good! (1,002 reviews)

"It was affordable and comfortable. Kenny was very helpful."

Reviewed on Jun 27, 2026

Days Inn by Wyndham Effingham

1602 Damron Court Effingham IL

Fully refundableReserve now, pay when you stay

$54 nightly

$61 total

Jul 5 - Jul 6

Total with taxes and fees

This hotel features a gym and a sauna. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate ...

6.2/10 (1,001 reviews)

"Renovation is awesome. Everything is new and classy. New carpet in halls will be a finale’ for a super job. We definitely recommend staying here. Good location, clean, attractive rooms and assorted breakfast choices."

Reviewed on Jun 21, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southern Illinois Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southern Illinois luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Southern Illinois to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Southern Illinois will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southern Illinois, and plan your next opulent escape.

Southern Illinois hotels essential information

Accommodation	1,143 hotels
Lowest Price	$61
Highest Price	$135
Popular hotels	Super 8 by Wyndham Troy IL/St. Louis Area, Rodeway Inn Effingham North, Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination, Super 8 by Wyndham Mt. Vernon IL, Days Inn by Wyndham Effingham, Super 8 by Wyndham Carbondale, Holiday Inn Express & Suites Mattoon by IHG, Quality Inn Effingham North