Cheap Flights to Southern Illinois from $44

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How Much Does it Cost To Fly To Southern Illinois?

The cheapest prices found with in the last 7 days for return flights were $68 and $44 for one-way flights to Southern Illinois for the period specified. Prices and availability are subject to change. Additional terms apply

Sat, Dec 12 - Mon, Dec 14
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$68 Roundtrip, found 2 hours ago
$68
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Sat, Dec 12 from Denver Intl. to Lambert-St. Louis Intl., returning Mon, Dec 14, priced at $68 found 2 hours ago
Wed, Nov 25 - Fri, Nov 27
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$117 Roundtrip, found 9 hours ago
$117
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Wed, Nov 25 from O'Hare Intl. to Lambert-St. Louis Intl., returning Fri, Nov 27, priced at $117 found 9 hours ago
OriginDestinationTravel DatesFlights From*
PGDMascoutahJanuary 16 to January 23$104
BNASt. LouisDecember 3 to December 4$117
ORFSt. LouisDecember 5 to December 7$173
DFWSt. LouisDecember 16 to January 6$210
AUSSt. LouisNovember 18 to November 25$221
DFWScott CityDecember 3 to December 7$258
RSWSt. LouisDecember 18 to December 19$330
DFWWest PaducahNovember 24 to November 27$350
CLTWest PaducahNovember 19 to November 24$387
PVDSt. LouisDecember 21 to December 26$398
DFWEvansvilleDecember 23 to December 29$474
CLTMarionNovember 19 to November 24$516
BNAEvansvilleDecember 14 to December 18$791
AUSWest PaducahNovember 26 to November 29$809
AUSScott CityNovember 20 to November 22$1,418
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
DCASt. LouisNovember 8 to November 16$345
PGDMascoutahNovember 8 to November 10$358
CLESt. LouisNovember 7 to November 9$367
CLTSt. LouisNovember 7 to November 21$392
AUSSt. LouisNovember 7 to November 11$403
ORFSt. LouisNovember 8 to November 15$538
DALSt. LouisNovember 7 to November 9$573
RSWSt. LouisNovember 8 to November 9$822
BNASt. LouisNovember 8 to November 12$1,163
*Prices include taxes and fees

Southern Illinois Flight Information

Traveling to
Southern Illinois
Lowest Price
$68
Number of Airlines Serving
Airlines Serving
Frontier Airlines, American Airlines
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Southern Illinois Accommodation Deals

Motel 6 Caseyville, IL - Caseyville Il

Motel 6 Caseyville, IL - Caseyville Il

2 out of 5
2431 Old Country Inn Dr Caseyville IL
$59 nightly
The price is $67 total per night from Nov 8 to Nov 9
$67 total
Nov 8 - Nov 9
Total with taxes and fees
Stay at this motel in Caseyville. Enjoy free parking, an outdoor pool, and a 24-hour front desk. Popular attractions Pleasant Ridge Park and Cahokia Mounds State ...
Opens in a new windowMotel 6 Caseyville, IL - Caseyville Il
Days Inn by Wyndham Charleston

Days Inn by Wyndham Charleston

2 out of 5
810 West Lincoln Avenue Charleston IL
$82 nightly
The price is $91 total per night from Nov 29 to Nov 30
$91 total
Nov 29 - Nov 30
Total with taxes and fees
Stay at this hotel in Charleston. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
Opens in a new windowDays Inn by Wyndham Charleston
Super 8 by Wyndham Marion

Super 8 by Wyndham Marion

2 out of 5
2601 Vernell Rd Marion IL
$74 nightly
The price is $89 total per night from Nov 6 to Nov 7
$89 total
Nov 6 - Nov 7
Total with taxes and fees
Book a stay at this business-friendly motel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Opens in a new windowSuper 8 by Wyndham Marion
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Americas Best Value Inn West Frankfort

Americas Best Value Inn West Frankfort

2.5 out of 5
1001 Factory Outlet Blvd West Frankfort IL
$74 nightly
The price is $82 total per night from Nov 30 to Dec 1
$82 total
Nov 30 - Dec 1
Total with taxes and fees
Stay at this motel in West Frankfort. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (541 reviews)
"Infested with rodents."

Reviewed on Oct 28, 2026

Opens in a new windowAmericas Best Value Inn West Frankfort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Southern Illinois

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area

2 out of 5
910 Edwardsville Rd Troy IL
$68 nightly
The price is $75 total per night from Nov 11 to Nov 12
$75 total
Nov 11 - Nov 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Troy. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,001 reviews)
"Great value for the price"

Reviewed on Nov 4, 2026

Opens in a new windowSuper 8 by Wyndham Troy IL/St. Louis Area
Rodeway Inn Effingham North

Rodeway Inn Effingham North

2 out of 5
1400 Thelma Keller Ave Effingham IL
$69 nightly
The price is $76 total per night from Nov 16 to Nov 17
$76 total
Nov 16 - Nov 17
Total with taxes and fees
Stay at this motel in Effingham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Opens in a new windowRodeway Inn Effingham North
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

3.5 out of 5
100 E Front St Metropolis IL
$117 nightly
The price is $130 total per night from Dec 6 to Dec 7
$130 total
Dec 6 - Dec 7
Total with taxes and fees
Stay at this hotel in Metropolis. Enjoy free parking, 2 restaurants, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.4/10 Very Good! (1,000 reviews)
"Hotel was very clean and well maintained"

Reviewed on Nov 3, 2026

Opens in a new windowHarrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
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Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL

2.5 out of 5
401 S 44th St Mount Vernon IL
$73 nightly
The price is $83 total per night from Nov 8 to Nov 9
$83 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Opens in a new windowSuper 8 by Wyndham Mt. Vernon IL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Southern Illinois

Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

2.5 out of 5
1306 Halfway Road Marion IL
$106 nightly
The price is $127 total per night from Nov 15 to Nov 16
$127 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,001 reviews)
"The property was very well maintained. The staff was friendly and helpful. The room was clean and comfortable. I couldn't give 5 stars solely based on toilet bowl grime."

Reviewed on Nov 4, 2026

Opens in a new windowCountry Inn & Suites by Radisson, Marion, IL
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
145 North 44th Street  Mount Vernon IL
$108 nightly
The price is $122 total per night from Dec 6 to Dec 7
$122 total
Dec 6 - Dec 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Opens in a new windowDrury Plaza Hotel Mt. Vernon
Comfort Inn & Suites O'Fallon - St. Louis Area

Comfort Inn & Suites O'Fallon - St. Louis Area

2 out of 5
116 Regency Park O'Fallon IL
$56 nightly
The price is $65 total per night from Nov 25 to Nov 26
$65 total
Nov 25 - Nov 26
Total with taxes and fees
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Opens in a new windowComfort Inn & Suites O'Fallon - St. Louis Area
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Holiday Inn Express & Suites Effingham by IHG

Holiday Inn Express & Suites Effingham by IHG

2.5 out of 5
1604 West Fayette Avenue Effingham IL
$118 nightly
The price is $132 total per night from Dec 6 to Dec 7
$132 total
Dec 6 - Dec 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,000 reviews)
"Amazing staff and experience from the moment I walked through the doors. Helpful, knowledgeable, professional and just kind. Brilliantly clean room, freshly ground coffee… they’re doing it right."

Reviewed on Oct 31, 2026

Opens in a new windowHoliday Inn Express & Suites Effingham by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Southern Illinois Flight and Hotel Packages

Southern Illinois flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG

3.5 out of 5
Price was $328, price is now $288 per person
$288
per person
Dec 15 - Dec 17
found 14 hours ago
Roundtrip flight included
Charlotte (CLT) to St. Louis (STL)
The Knight Center at Washington University

The Knight Center at Washington University

2.5 out of 5
Price was $518, price is now $443 per person
$443
per person
Dec 11 - Dec 13
found 1 day ago
Roundtrip flight included
Charlotte (CLT) to St. Louis (STL)
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Price was $1,709, price is now $1,512 per person
$1,512
per person
Dec 23 - Dec 28
found 1 day ago
Roundtrip non-stop flight included
Greensboro (GSO) to St. Louis (STL)
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Need a Car For After Your Flight?

Mini Van

  • 7 people
  • Unlimited mileage
Saint Louis, Missouri, USA

$71

$183 total
found 1 day ago
Mini Van undefined

Economy

  • 4 people
  • Unlimited mileage
Saint Louis, Missouri, USA

$81

$207 total
found 1 day ago
Economy undefined

Midsize

  • 5 people
  • Unlimited mileage
Saint Louis, Missouri, USA

$81

$206 total
found 1 day ago
Midsize undefined

Compact

  • 5 people
  • Unlimited mileage
Saint Louis, Missouri, USA

$81

$207 total
found 1 day ago
Compact undefined

Frequently asked questions

How much is the cheapest flight to Southern Illinois?
A roundtrip flight to Southern Illinois cost as little as $68 in the last seven days. Once you've decided on your travel dates, we'll help you grab a good deal. This price was available on Travelocity for flights to Southern Illinois departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly to Southern Illinois?
According to Travelocity's direct return flight demand between January and December last year, December is the cheapest period to jet off to Southern Illinois. Look for flights across this month and snag a terrific deal today.
How can I check my flight status to Southern Illinois?
There are a few simple ways to check your fight status. You can find all the necessary details in our "Trips" portal, which is located at the top of our homepage. Log in or create an account — you'll then be able to browse and amend your bookings whenever you need to. If you're already traveling, the Travelocity app can also help you check the status of your flight to Southern Illinois, as well as share details with any members of your family flying with you.
How do I find the best deals on flights to Southern Illinois?
It's good to book ahead of time, and if you can, avoid traveling during peak periods. Another great way to save is by clicking the "Flexible dates" box at the top of the page after searching for your flights. It's an easy way to compare prices for surrounding days. In the last seven days, the best price for a roundtrip flight to Southern Illinois was $68. This price was available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Why should I book my flight to Southern Illinois with Travelocity?
An exciting vacation is just a click away when you book your trip with Travelocity. With a wide selection of choices and great deals on cheap family flights, rental cars and more, we make it simple to locate the best prices for you. You can also take advantage of our 24/7 customer support and free cancellations on most hotels during your trip. Wander with us and secure your cheap flights to Southern Illinois today.
How much is a flight to Southern Illinois on average?
Based on prices found over the last seven days, roundtrip flights to Southern Illinois cost between $68 and $1,418. When you're ready to hop on a plane, Travelocity will help you find a fare that won't blow your budget. These prices were available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What can I expect on a flight to Southern Illinois?
If you have a long-haul flight to Southern Illinois, you can usually expect drinks, meals and entertainment on board. Airlines like to make longer flights as pleasant as possible. Shorter journeys — as well as flights offered by budget airlines — may not have as many inclusions. If you're chasing cheap flights for family vacations with a low-cost carrier, you'll usually have to pay extra for snacks, drinks and entertainment.

Plane Tickets To Southern Illinois

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Southern Illinois. Browse through our inventory to explore a wide range of cheap flights to Southern Illinois to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Southern Illinois as you anxiously await to exit the plane and explore what Southern Illinois has to offer. Considering all the amazing local food and culture in Southern Illinois, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Southern Illinois to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Southern Illinois without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Southern Illinois with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Southern Illinois today!

Explore More Ways to Travel with Travelocity

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.