Cheap Flights to Southern Illinois from $95
Wander Wisely with exceptional service, 24/7 supportOpens in a new window
Feel at ease with free flight cancellations within 24 hours of booking
Change your flight without a fee on select flights
How Much Does it Cost To Fly To Southern Illinois?
The cheapest prices found with in the last 7 days for return flights were $101 and $95 for one-way flights to Southern Illinois for the period specified. Prices and availability are subject to change. Additional terms apply
DTW
Detroit Metropolitan Wayne County
STL
Lambert-St. Louis Intl.
$185 Roundtrip, found 5 days ago
$185
Roundtrip
found 5 days ago
OMA
Eppley Field
STL
Lambert-St. Louis Intl.
$257 Roundtrip, found 5 days ago
$257
Roundtrip
found 5 days ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| DEN | St. Louis | June 3 to June 9 | $101 |
| LGA | St. Louis | August 11 to August 12 | $200 |
| AUS | St. Louis | June 3 to June 5 | $206 |
| FLL | St. Louis | June 9 to June 12 | $231 |
| JFK | St. Louis | May 26 to May 27 | $290 |
| FLL | Evansville | June 10 to June 17 | $414 |
| FLL | West Paducah | May 16 to May 30 | $424 |
| JFK | Marion | July 9 to July 10 | $424 |
| AUS | Evansville | June 9 to June 23 | $424 |
| FLL | Marion | July 17 to July 25 | $463 |
| FLG | St. Louis | July 16 to July 21 | $512 |
| DEN | Evansville | May 22 to May 27 | $576 |
| JFK | Scott City | July 13 to July 20 | $584 |
| AUS | Scott City | May 22 to May 24 | $710 |
| DEN | Scott City | May 24 to May 26 | $1,072 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| AUS | St. Louis | May 16 to May 17 | $329 |
| DEN | St. Louis | May 17 to May 18 | $342 |
| FLL | St. Louis | May 15 to May 18 | $349 |
| FLL | West Paducah | May 16 to May 30 | $424 |
| LGA | St. Louis | May 16 to May 18 | $436 |
| JFK | St. Louis | May 16 to May 18 | $461 |
| AUS | Evansville | May 17 to May 28 | $505 |
| JFK | Evansville | May 15 to May 22 | $569 |
| LGA | Evansville | May 15 to May 22 | $599 |
| EWN | St. Louis | May 15 to May 18 | $630 |
| PGV | St. Louis | May 15 to May 18 | $662 |
Southern Illinois Flight Information
Traveling to | Southern Illinois |
|---|---|
Lowest Price | $101 |
Number of Airlines Serving | |
Airlines Serving | Frontier Airlines, Southwest Airlines |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Southern Illinois Accommodation Deals
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$60 nightly
The price is $67 total per night from May 11 to May 12
$67 total
May 11 - May 12
Total with taxes and fees
Stay at this motel in Caseyville. Enjoy free parking, an outdoor pool, and a 24-hour front desk. Popular attractions Pleasant Ridge Park and Cahokia Mounds State ...
6.4/10 (1,002 reviews)
If you want to step on a used needle. This is the place to go. You get what you pay for
Reviewed on May 3, 2026
Days Inn by Wyndham Charleston
810 West Lincoln Avenue Charleston IL
$82 nightly
The price is $91 total per night from May 10 to May 11
$91 total
May 10 - May 11
Total with taxes and fees
Stay at this hotel in Charleston. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (782 reviews)
Gret staff.
Reviewed on May 7, 2026
Super 8 by Wyndham Marion
2601 Vernell Rd Marion IL
$69 nightly
The price is $83 total per night from May 17 to May 18
$83 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly motel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (1,003 reviews)
The property dud not have an adequate continental breakfast and the room was not thiriyghly cleaned, we had to ask for towels. We stated two days they wouldnt change the linen.
Reviewed on May 6, 2026
Save an average of 15% on thousands of hotels when you're signed in
Americas Best Value Inn West Frankfort
1001 Factory Outlet Blvd West Frankfort IL
$68 nightly
The price is $75 total per night from May 10 to May 11
$75 total
May 10 - May 11
Total with taxes and fees
Stay at this motel in West Frankfort. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (497 reviews)
Room 104, It's a queen handicap accessible room..tub with shower chair, standard 17 inch toilet which I was grateful for. Bring your own shower gel they only hv that rough bar soap.. Room has a mini fridge and microwave..both were clean..the bed was a mattress on top if a steel frame. I slept fine ...
Reviewed on May 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Southern Illinois
Super 8 by Wyndham Troy IL/St. Louis Area
910 Edwardsville Rd Troy IL
$68 nightly
The price is $75 total per night from May 17 to May 18
$75 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Troy. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (1,005 reviews)
Check in was fast room and pool area where clean Breakfast needed more options
Reviewed on May 2, 2026
Rodeway Inn Effingham North
1400 Thelma Keller Ave Effingham IL
$70 nightly
The price is $78 total per night from May 10 to May 11
$78 total
May 10 - May 11
Total with taxes and fees
Stay at this motel in Effingham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
100 E Front St Metropolis IL
$122 nightly
The price is $135 total per night from Jun 7 to Jun 8
$135 total
Jun 7 - Jun 8
Total with taxes and fees
Stay at this hotel in Metropolis. Enjoy free parking, 2 restaurants, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.2/10 Very Good! (1,001 reviews)
Easy check in. Nice staff
Reviewed on Apr 28, 2026
Save an average of 15% on thousands of hotels when you're signed in
Super 8 by Wyndham Mt. Vernon IL
401 S 44th St Mount Vernon IL
$69 nightly
The price is $79 total per night from May 25 to May 26
$79 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,006 reviews)
It was fine. The price was right.
Reviewed on May 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Southern Illinois
Country Inn & Suites by Radisson, Marion, IL
1306 Halfway Road Marion IL
$105 nightly
The price is $126 total per night from May 31 to Jun 1
$126 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,004 reviews)
Clean room friendly staff
Reviewed on May 7, 2026
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
$109 nightly
The price is $123 total per night from May 18 to May 19
$123 total
May 18 - May 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,695 reviews)
Room is clean, service very friendly and helpful.Thank you for everything!
Reviewed on May 8, 2026
Comfort Inn & Suites O'Fallon - St. Louis Area
116 Regency Park O'Fallon IL
$76 nightly
The price is $87 total per night from May 31 to Jun 1
$87 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.4/10 (145 reviews)
Clean room. Convenient location. Breakfast ends too early on weekends. Friendly staff
Reviewed on May 8, 2026
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Express & Suites Effingham by IHG
1604 West Fayette Avenue Effingham IL
$140 nightly
The price is $157 total per night from May 24 to May 25
$157 total
May 24 - May 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,003 reviews)
The Sauna and pool makes the stay here worth every penny. 4 stars for the breakfast and gym, and 5 stars for everything else.
Reviewed on May 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Southern Illinois Flight and Hotel Packages
Southern Illinois flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Don't see what you're looking for?
See all available trips from New York to Southern Illinois
View all tripsNeed a Car For After Your Flight?
Standard SUV
Evansville, Indiana, USA
$67
$199 total
found 3 days ago
Mini Van
Evansville, Indiana, USA
$69
$203 total
found 3 days ago
Midsize SUV
Evansville, Indiana, USA
$72
$211 total
found 3 days ago
Special
Evansville, Indiana, USA
$73
$213 total
found 3 days ago
Lowest prices found within the past 3 days. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Plane Tickets To Southern Illinois
Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Southern Illinois. Browse through our inventory to explore a wide range of cheap flights to Southern Illinois to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Southern Illinois as you anxiously await to exit the plane and explore what Southern Illinois has to offer. Considering all the amazing local food and culture in Southern Illinois, we won't hold this against you.
When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Southern Illinois to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Southern Illinois without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Southern Illinois with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Southern Illinois today!
Explore More Ways to Travel with Travelocity
- Hotels near Wayne Fitzgerrell State Park
- 4 Star Hotels in Mount Vernon
- 5 Star Hotels in Mount Vernon
- Cabins in Mount Vernon
- Convention Center Hotels in Mount Vernon
- Drury Inn & Suites Hotels in Mount Vernon
- Golf Resorts & in Mount Vernon
- Hotels with Pools in Mount Vernon
- Hotels with Balconies in Mount Vernon
- Hotels with Bar in Mount Vernon
- Hotels with Free Breakfast in Mount Vernon
- Hotels with Free Parking in Mount Vernon
- Hotels with Hot Tubs in Mount Vernon
- Hotels with an Indoor Pool in Mount Vernon
- Hotels with Restaurants in Mount Vernon
- Independent Hotels in Mount Vernon
- Luxury Hotels in Mount Vernon
- Pet Friendly Hotels in Mount Vernon
- Spa Resorts & in Mount Vernon
- Hotel Wedding Venues Hotels in Mount Vernon
- Mount Vernon Hotels
- Lodges in Mount Vernon
- Motels in Mount Vernon
- Vacation Homes in Mount Vernon
- Guest Houses in Whittington
- Golf Resorts & in Whittington
- Pet Friendly Hotels in Whittington
- Whittington Hotels
- Lodges in Whittington
- Hotels near Veterans Memorial Park
- Hotels near Dix Village Hall
- Cabins in Bonnie
- Apartments in Ina
- Ina Hotels
- Motels in Ina
- Apartments in Bluford
- Cabins in Bluford
- Motels in Bluford
- Vacation Homes in Bluford
- Hotels near Pheasant Hollow Winery
- Cabins in Sesser
- Sesser Hotels
- Rv Parks in Sesser
- 3 Star Hotels in Ewing
- 4 Star Hotels in Ewing
- Cabins in Ewing
- Ewing Hotels
- Rv Parks in Ewing
- Hotels near Rend Lake College
- Apartments in Waltonville
- Cabins in Belle Rive
- Vacation Homes in Belle Rive
- 4 Star Hotels in Opdyke
- Opdyke Hotels
- Cabins in Dix
- Dix Hotels
- Motels in Dix
- Vacation Homes in Dix
- Hotels near Rend Lake
- Hotels near Mount Vernon Outland
- Flights to Mount Vernon
- Flights to Alto Pass
- Flights to Fairfield
- Flights to Carterville
- Flights to O'Fallon
- Flights to Lebanon
- Flights to Mascoutah
- Flights to Muddy
- Flights to Patoka
- Flights to MidAmerica-St. Louis
- Flights to Ozark
- Flights to Flora
- Flights to Cisne
- Flights to West Frankfort
- Flights to Goreville
- Flights to Carlyle
- Flights to Centralia
- Flights to Marion
- Flights to Murphysboro
- Flights to Benton
- Flights to Mount Carmel
- Flights to Carbondale
- Flights to Nashville
- Flights to Menard
- Flights from Mount Vernon Outland
- Flights to Scott Air Force Base
- Flights to Vandalia
- Flights to Effingham
- Flights to Du Quoin
- Flights to Highland
- Flights to Herrin