Explore top 2026 4 Star Hotels in Southern Illinois

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Top Southern Illinois 4 Star hotels

Walker's Bluff Casino Resort

Walker's Bluff Casino Resort

4.5 out of 5
777 Walkers Bluff Way Carterville IL
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $173 total per night from Nov 10 to Nov 11
$173 total
Nov 10 - Nov 11
Total with taxes and fees
This luxury resort features a casino, a full-service spa, and 3 restaurants. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
9.4/10 Exceptional! (543 reviews)
"Came and saw an awesome Little River Band concert. Had an incredible dinner at Ruthie's. The event center was nice, very intimate. Great time at the Casino and nice clean bed to sleep in after. Perfect evening"

Reviewed on Nov 5, 2026

Opens in a new windowWalker's Bluff Casino Resort
DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon

4 out of 5
222 Potomac Blvd Mount Vernon IL
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $144 total per night from Nov 7 to Nov 8
$144 total
Nov 7 - Nov 8
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8.4/10 Very Good! (908 reviews)
"The property was basically fine. However, there were three in our party. We had only one bath towel in our room and enough shower gel for only one to shower. It was nearly impossible to make the room dark enough to sleep."

Reviewed on Oct 26, 2026

Opens in a new windowDoubleTree by Hilton Mt. Vernon
DoubleTree by Hilton Collinsville - St. Louis

DoubleTree by Hilton Collinsville - St. Louis

4 out of 5
1000 Eastport Plaza Dr Collinsville IL
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $124 total per night from Dec 2 to Dec 3
$124 total
Dec 2 - Dec 3
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8.2/10 Very Good! (1,000 reviews)
"Ujjj"

Reviewed on Oct 31, 2026

Opens in a new windowDoubleTree by Hilton Collinsville - St. Louis
Charleston House Bed & Breakfast Inn

Charleston House Bed & Breakfast Inn

4 out of 5
956 6th St Charleston IL
$75 nightly
The price is $83 total per night from Nov 15 to Nov 16
$83 total
Nov 15 - Nov 16
Total with taxes and fees
This bed & breakfast doesn't skimp on freebies - guests receive free English breakfast, free WiFi, and free self parking. Business travelers can take advantage ...
10/10 Exceptional! (21 reviews)
"I highly recommend this B&B."

Reviewed on Oct 16, 2026

Opens in a new windowCharleston House Bed & Breakfast Inn
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4 Star Hotels Southern Illinois

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Southern Illinois 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Southern Illinois will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Southern Illinois, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Southern Illinois hotel reviews by fellow wanderers

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