Explore top 2026 4 Star Hotels in Southern Illinois
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Southern Illinois 4 Star hotels

Walker's Bluff Casino Resort
"Came and saw an awesome Little River Band concert. Had an incredible dinner at Ruthie's. The event center was nice, very intimate. Great time at the Casino and nice clean bed to sleep in after. Perfect evening"
Reviewed on Nov 5, 2026

DoubleTree by Hilton Mt. Vernon
"The property was basically fine. However, there were three in our party. We had only one bath towel in our room and enough shower gel for only one to shower. It was nearly impossible to make the room dark enough to sleep."
Reviewed on Oct 26, 2026

DoubleTree by Hilton Collinsville - St. Louis
"Ujjj"
Reviewed on Oct 31, 2026

Charleston House Bed & Breakfast Inn
"I highly recommend this B&B."
Reviewed on Oct 16, 2026
4 Star Hotels Southern Illinois
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Southern Illinois 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Southern Illinois will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Southern Illinois, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Southern Illinois hotel reviews by fellow wanderers

Drury Plaza Hotel Mt. Vernon
"It was a bit frustrating to get to because of the construction but that's out of their control. When we originally got there they had run out of the room we ordered and offered a cot for free. I was not happy with this because I paid extra for two beds. Eventually they were able to find a room that had two beds for no extra cost. It was nice they worked to get it adjusted in the end but whatever system is used for booking isn't the greatest. The room we were in was very clean however and comfortable."
More ways to wander Southern Illinois
Explore More Ways to Travel with Travelocity
- Hotels in Carbondale
- Hotels in Centralia
- Hotels in Du Quoin
- Hotels near Giant City State Park
- Hotels in Ina
- Hotels in Marion
- Cabins in Mount Vernon
- Americas Best Value Inn Mount Vernon
- Comfort Suites Mount Vernon
- DoubleTree by Hilton Mt Vernon
- Drury Plaza Hotel Mt Vernon
- Pool in Mount Vernon
- Balcony in Mount Vernon
- Free Breakfast in Mount Vernon
- Hot Tub in Mount Vernon
- Indoor Pool in Mount Vernon
- Dining in Mount Vernon
- Luxury in Mount Vernon
- Pet Friendly in Mount Vernon
- Royal Inn
- Spa in Mount Vernon
- Wedding in Mount Vernon
- Hotels in Mount Vernon
- Lodges in Mount Vernon
- Motels in Mount Vernon
- Hotels near Mount Vernon IL
- Privatevacationhomes in Mount Vernon
- Hotels in Opdyke
- Caravanparks in Southern Illinois
- Resorts in Southern Illinois
- Privatevacationhomes in Southern Illinois
- Motels in Southern Illinois
- Lodges in Southern Illinois
- Winery in Southern Illinois
- Waterpark in Southern Illinois
- Spa in Southern Illinois
- Ski in Southern Illinois
- Romantic in Southern Illinois
- River View in Southern Illinois
- Pet Friendly in Southern Illinois
- Luxury in Southern Illinois
- Smoking in Southern Illinois
- Indoor Pool in Southern Illinois
- Hot Tub in Southern Illinois
- Balcony in Southern Illinois
- Pool in Southern Illinois
- Early Check-in in Southern Illinois
- Historical in Southern Illinois
- Family Friendly in Southern Illinois
- Budget in Southern Illinois
- Casino in Southern Illinois
- Best Western in Southern Illinois
- Beach in Southern Illinois
- Adults Only in Southern Illinois
- Aparthotels in Southern Illinois
- Cottages in Southern Illinois
- Cabins in Southern Illinois
- 4 Star Hotels in Carbondale
- 5 Star Hotels in Benton
- Bedandbreakfast in Southern Illinois
- Apartments in Southern Illinois
- Agritourism in Southern Illinois
- Hotels in Salem
- Hotels near Rend Lake
- Hotels near Rend Lake College
- 5 Star Hotels in Hoyleton
- Cabins in Belle Rive
- Hotels in Benton
- Privatevacationhomes in Bluford
- Cabins in Bonnie
- Motels in Bonnie




