Book Hotels in Lupus, MO
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Top Lupus hotels

Step Back in Time Near The Missouri River
Jamestown MO
Fully refundable
The price is $264 total per night from Nov 16 to Nov 17
$264 total
per night
Nov 16 - Nov 17
This cottage features a garden, laundry facilities, and barbecue grills.
"Very clean, awesome decor. We loved the peace and quiet, the house was clean, plenty of room, and the host, Andrew was friendly and easy to work with!"
Reviewed on Sep 14, 2026

Quiet Riverfront Cottage on Missouri River
Jamestown MO
Fully refundable
The price is $261 total per night from Nov 16 to Nov 17
$261 total
per night
Nov 16 - Nov 17
This cottage features a garden, laundry facilities, and barbecue grills.
"Lovely home."
Reviewed on Oct 4, 2026

Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
The price is $134 total per night from Dec 6 to Dec 7
$134 total
per night
Dec 6 - Dec 7
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...
"This hotel was nice and a new option for us. All was great"
Reviewed on Nov 13, 2026

Hotel Blu
3402 Interstate 70 Dr SE Columbia MO
Fully refundableReserve now, pay when you stay
The price is $69 total per night from Nov 16 to Nov 17
$69 total
per night
Nov 16 - Nov 17
An indoor pool, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A grocery/convenience store, a lobby fireplace, ...
"The site was clean and comfortable."
Reviewed on Nov 14, 2026

Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
The price is $69 total per night from Nov 22 to Nov 23
$69 total
per night
Nov 22 - Nov 23
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...

Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
The price is $115 total per night from Nov 22 to Nov 23
$115 total
per night
Nov 22 - Nov 23
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Fully refundable
The price is $90 total per night from Dec 6 to Dec 7
$90 total
per night
Dec 6 - Dec 7
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...

Wingate by Wyndham - Columbia
3101 Wingate Ct Columbia MO
Fully refundableReserve now, pay when you stay
The price is $97 total per night from Nov 22 to Nov 23
$97 total
per night
Nov 22 - Nov 23
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...

Wyndham Executive Center Columbia
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
The price is $112 total per night from Nov 29 to Nov 30
$112 total
per night
Nov 29 - Nov 30
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Lupus hotel reviews by fellow wanderers

Hotel Blu
4 out of 5
Posted 8 hours ago
Travelocity Verified Review
"The site was clean and comfortable."
A verified traveler stayed at Hotel Blu
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