Book Hotels in Lake City, SC

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Top Lake City hotels

The Inn at the Crossroads

The Inn at the Crossroads

2 out of 5
128 West Main Street Lake City SC
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $150 total per night from Feb 8 to Feb 9
$150 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Very nice. Would stay again. Would like more breakfast options but understand that stay may have been at a low occupancy time. Train whistles a little disturbing throughout the night. Beautiful lobby.

Reviewed on Jan 12, 2026

Opens in a new windowThe Inn at the Crossroads
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $107 total per night from Feb 1 to Feb 2
$107 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
The staff was friendly and the room was clean.

Reviewed on Jan 19, 2026

Opens in a new windowComfort Inn & Suites Florence Center Area
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

2.5 out of 5
3000 W Radio Dr Florence SC
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $118 total per night from Jan 27 to Jan 28
$118 total
Jan 27 - Jan 28
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
Breakfast was far could use more options that are healthy . Rooms were very nice and super clean.

Reviewed on Jan 17, 2026

Opens in a new windowHampton Inn & Suites Florence Center
Residence Inn Marriott Florence

Residence Inn Marriott Florence

3 out of 5
2660 Hospitality Blvd Florence SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Jan 25 to Jan 26
$111 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free continental ...
I gave it four stars because they was a five dollar parking fee that’s charged on the credit card you leave for incidentals I was not aware of the parking fee. We only stayed one night so I guess it’s five dollars per night for parking. Other than that. Everything was great. Rooms were clean. Breakfast ...

Reviewed on Jan 5, 2026

Opens in a new windowResidence Inn Marriott Florence
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3 out of 5
2650 Hospitality Boulevard Florence SC
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $118 total per night from Jan 21 to Jan 22
$118 total
Jan 21 - Jan 22
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Very clean & neat room, reg size refrigerator & grill areas nice, the shower had oroblem with achieving full water spray (half was coming out of tub faucet), water only lukewarm

Reviewed on Jan 14, 2026

Opens in a new windowTownePlace Suites by Marriott Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $94 total per night from Feb 2 to Feb 3
$94 total
Feb 2 - Feb 3
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
The room was as described. It was neat, clean and spotless with 1 kimg size bed, and 1 sofa bed.

Reviewed on Jan 17, 2026

Opens in a new windowQuality Inn & Suites Florence Civic Center
Quality Inn & Suites Lake City

Quality Inn & Suites Lake City

2.5 out of 5
202 N Ron Mcnair Blvd Lake City SC
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $117 total per night from Feb 15 to Feb 16
$117 total
Feb 15 - Feb 16
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Yes

Reviewed on Dec 12, 2025

Opens in a new windowQuality Inn & Suites Lake City
Days Inn by Wyndham Lake City

Days Inn by Wyndham Lake City

2 out of 5
170 S Ron Mcnair Blvd Lake City SC
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $116 total per night from Jan 26 to Jan 27
$116 total
Jan 26 - Jan 27
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
The room was clean and the staff was very nice

Reviewed on Jan 16, 2026

Opens in a new windowDays Inn by Wyndham Lake City
Security inn & suites

Security inn & suites

2 out of 5
319 Sumter St Lake City SC
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $118 total per night from Jan 25 to Jan 26
$118 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
Opens in a new windowSecurity inn & suites
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Lake City hotels

The Inn at the Crossroads

The Inn at the Crossroads

128 West Main Street Lake City SC
$133 nightly
The price is $150 total per night from Feb 8 to Feb 9
$150 total
Feb 8 - Feb 9
Total with taxes and fees
9.4/10 Exceptional! (847 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Lake City Hotel & Travel Guide

Within a 6-mile (10-kilometer) radius of the heart of Lake City, with Travelocity's reservations page you can find a limited, yet excellent selection of places to kick your feet up. Within an easy commute to Lake City, travelers will find 2 suitable lodging options.

If you are hoping to find a hotel that is no more than an easy walk from central Lake City, Days Inn Lake City and The Inn at the Crossroads will be perfect.

If you are in the downtown area of Lake City, it is around 13 miles (21 kilometers) to the Signature Boutique Hotel.

Would you like to go further afield? South Carolina Midlands boasts many impressive options. South Carolina Midlands is famous for rolling hills. Commonly visited visitor sights include historic mansions and gardens. In this fascinating part of United States of America adventurous visitors can partake in hiking.

35 miles (59 kilometers) to the northwest of Lake City, you can reach Bishopville, which is where you can enjoy South Carolina Cotton Museum and Lee State Park. A few Bishopville places to stay include the Americas Best Value Inn and Econo Lodge Bishopville. 40 miles (63 kilometers) northwest of Lake City, is Hartsville, which boasts the Fairfield Inn by Marriott Hartsville and Quality Inn. During your time in Hartsville, make your way to the Coker College and Hartsville Museum.

If you are into sports and like to watch thrilling games you and your family could take a trip to Myrtle Beach Speedway, which is found 45 miles (75 kilometers) to the east of Lake City. Find a Travelocity-listed hotel right in the thick of the action at the Bluegreen Vacations Harbour Lights, Ascend Resort Collection or the Hampton Inn Myrtle Beach West.

Florence Regional Airport is a primary arrival point for air travel, and is 25 miles (37 kilometers) from Lake City's downtown. Travelocity-listed accommodation nearby include Hotel Florence, an Ascend Hotel Collection Member and Motel 6 Florence Historic Downtown.

Frequently asked questions

What are the top kid-friendly hotels in Lake City?
Family getaways are where amazing memories are made, but it's no secret that traveling with little ones can be daunting. These kid-friendly Lake City hotels come with perks that aim to keep adventurers of all ages comfortable and happy: The Inn at the Crossroads will help make your next trip the best one yet. It features plenty of conveniences aimed at families, such as complimentary breakfast and a pillowtop mattress. Also check out Days Inn by Wyndham Lake City. It comes with a swimming pool, complimentary breakfast and plenty of opportunities to spend time as a family.
Where can I find cheap hotels in Lake City?
At Travelocity you'll find really nice hotels in Lake City at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Lake City rather than in Lake City. We may find you even better rates, too.
How do I find the best Lake City hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Lake City then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Lake City?
The cheapest hotel in Lake City is $94. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Lake City?
There are 94 hotels in Lake City on Travelocity.
What are the best hotels in Lake City?
Lake City has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Lake City for you!
When is the best time to visit Lake City?
If you want the joy of a fun-filled trip in peak season, visit Lake City during April, June and November. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, July and September.
When is the cheapest time to stay in Lake City?
Based on historic data is usually the cheapest month to visit Lake City. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Lake City?
There are multiple hotels in Lake City that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Lake City. We have plenty of kid-friendly hotels in Lake City to choose from on Travelocity!
Why book a hotel in Lake City through Travelocity?
Because we have the top hotels in Lake City! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Lake City on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

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