Explore 54 Luxury Hotels in Southern Illinois

Name: Days Inn by Wyndham Effingham
Price range: $62 total
Rating: 6

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Best Luxury Hotels in Southern Illinois

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

100 E Front St Metropolis IL

$117 nightly

$130 total

Apr 16 - Apr 17

Total with taxes and fees

This hotel features a casino and 2 restaurants. Relax with a drink at the bar/lounge and enjoy perks like free self parking and free WiFi. A snack bar/deli, ...

8.2/10 Very Good! (1,001 reviews)

Booked because of the Tesla charging stations. We were given a king bed room on the 7th floor. It was perfect for our one night stay. It was clean, quiet & very comfortable.

Reviewed on Mar 18, 2026

Holiday Inn Express & Suites Mattoon by IHG

121 Swords Dr Mattoon IL

$101 nightly

$113 total

Mar 22 - Mar 23

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 24-hour ...

8.2/10 Very Good! (770 reviews)

Lots of problems with hotel. Pool was out of order. Tv didn’t work in room, tiles broken in bathroom

Reviewed on Mar 10, 2026

Super 8 by Wyndham Troy IL/St. Louis Area

910 Edwardsville Rd Troy IL

$68 nightly

$75 total

Mar 24 - Mar 25

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...

8/10 Very Good! (1,001 reviews)

Had the DND on the door and housekeeping came in anyway

Reviewed on Mar 16, 2026

Super 8 by Wyndham Mt. Vernon IL

401 S 44th St Mount Vernon IL

Fully refundableReserve now, pay when you stay

$79 nightly

$90 total

Mar 19 - Mar 20

Total with taxes and fees

This hotel features free WiFi in public areas, free newspapers, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...

7.8/10 Good! (1,002 reviews)

Coffee pot in the room

Reviewed on Mar 16, 2026

Rodeway Inn Effingham North

1400 Thelma Keller Ave Effingham IL

Fully refundableReserve now, pay when you stay

$55 nightly

$61 total

Mar 19 - Mar 20

Total with taxes and fees

Free self parking is available and the motel's front desk is staffed around-the-clock. WiFi in public areas is free. A picnic area is also provided.

7.6/10 Good! (1,001 reviews)

The person behind the desk is actually on a video screen, taking/talking your info. Only person that I seen was a cleaning person. We had requested, and they obliged,a bottom floor due to a broken foot. They do allow pets.( there was hairs) Room had a lingering smell of cigarette smoke. Says its ...

Reviewed on Mar 15, 2026

Suite Dreams Motel Mattoon I 57

300 Broadway Avenue East Mattoon IL

Fully refundableReserve now, pay when you stay

$82 nightly

$90 total

Mar 19 - Mar 20

Total with taxes and fees

A restaurant and a gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...

7.4/10 Good! (551 reviews)

Enjoyed our time friendly people and clean

Reviewed on Mar 2, 2026

Super 8 by Wyndham Carbondale

1180 E Main St Carbondale IL

Fully refundableReserve now, pay when you stay

$68 nightly

$78 total

Mar 19 - Mar 20

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Multilingual staff at the 24-hour front desk ...

7.4/10 Good! (1,000 reviews)

The room was fairly clean and the staff was very friendly. The breakfast leaves a lot to be desired. It was wrapped cinnamon buns, dry cereal and bad coffee. There were coffee packets and cups in the room, but no coffee maker. An OK place to spend the night, but nothing to write home about.

Reviewed on Mar 9, 2026

Days Inn by Wyndham Effingham

1602 Damron Court Effingham IL

Fully refundableReserve now, pay when you stay

$55 nightly

$62 total

Mar 29 - Mar 30

Total with taxes and fees

This hotel features a gym and a sauna. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate ...

6/10 (1,000 reviews)

The staff was very kind ,rooms were updated and very comfortable was really impressed for the price

Reviewed on Mar 1, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southern Illinois Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southern Illinois luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Southern Illinois to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Southern Illinois will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southern Illinois, and plan your next opulent escape.

Southern Illinois hotels essential information

Accommodation	1,158 hotels
Lowest Price	$61
Highest Price	$130
Popular hotels	Super 8 by Wyndham Troy IL/St. Louis Area, Rodeway Inn Effingham North, Suite Dreams Motel Mattoon I 57, Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination, Super 8 by Wyndham Mt. Vernon IL, Days Inn by Wyndham Effingham, Super 8 by Wyndham Carbondale, Holiday Inn Express & Suites Mattoon by IHG

Popular Luxury Stays in Southern Illinois

5 Stars Luxury stays in Southern Illinois

Luxury stays in Southern Illinois with spa

Recent Southern Illinois Hotel Reviews By Fellow Wanderers

Drury Plaza Hotel Mt. Vernon

5 out of 5

Posted 9 hours ago

Travelocity Verified Review

"It was a brief stay but everything was good. Very busy as I believe the front desk said they were full the night we stayed. Newly renovated and nice. Very good breakfast. "

A verified traveler stayed at Drury Plaza Hotel Mt. Vernon