Book Hotels in Dona Ana, NM
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Top Dona Ana hotels

Drury Inn & Suites Las Cruces
1631 Hickory Loop Las Cruces NM
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $133 total per night from Jun 21 to Jun 22
$133 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"When visiting Las Cruces NM we always stay here. The staff has always been pleasant and helpful. The breakfast has a little of everything. The 5:30 Kickback is great amenity."
Reviewed on Jun 2, 2026

Hotel Encanto de Las Cruces
705 S Telshor Blvd Las Cruces NM
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $147 total per night from Jun 8 to Jun 9
$147 total
Jun 8 - Jun 9
Total with taxes and fees
A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling for business? Take advantage of the 24-hour business center, ...
"Excellent overall!!"
Reviewed on Jun 6, 2026

Comfort Suites Las Cruces I-25 North
236 N Telshor Blvd. Las Cruces NM
Fully refundable
$116 nightly
The price is $133 total per night from Jul 5 to Jul 6
$133 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"Spacious room for active toddler"
Reviewed on Jun 5, 2026

Best Western Mission Inn
1765 S Main St Las Cruces NM
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $99 total per night from Jun 8 to Jun 9
$99 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
"This hotel deserves a 10. The rooms are very clean and comfortable. The AC worked great and the pool and garden are well maintained. The do need to repair the parking as it has a lot of puddles, but not extremely bad. The staff was friendly and the breakfast was hot and plentiful. The train passes ..."
Reviewed on Jun 6, 2026

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
1500 Hickory Dr Las Cruces NM
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $70 total per night from Jul 5 to Jul 6
$70 total
Jul 5 - Jul 6
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
"Would stay again! Great location and close to a lot of things."
Reviewed on Jun 6, 2026

Days Inn by Wyndham Las Cruces
755 Avenida De Mesilla Las Cruces NM
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $59 total per night from Jun 8 to Jun 9
$59 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"Room floor had bits of food and dirt, the sink stopper was not there, the shower stopper was laying on the shelf, AC was falling apart and never shut off, the matress was sloping toward the head board ( we spun the mattress around to sleep) breakfast was not as advertised and empty when we went at ..."
Reviewed on Jun 6, 2026

Ramada Hotel & Conference Center by Wyndham Las Cruces
201 E University Avenue Las Cruces NM
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $93 total per night from Jun 8 to Jun 9
$93 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the conference center and conference ...
"Hotel is older. It is going through a remodel so certain things weren't working. AC in main lobby and in rooms was rough. Pool was nice. I didn't see much for breakfast, but I think dining and bar service are down due to renovation. Also be careful of the tub, it was really high up when I tried to ..."
Reviewed on Jun 7, 2026

Comfort Suites University Las Cruces
2101 S Triviz Drive Las Cruces NM
Fully refundable
$84 nightly
The price is $98 total per night from Jun 28 to Jun 29
$98 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Everything was good, maybe more breakfast options. I highly recommend"
Reviewed on Jun 1, 2026

La Quinta Inn by Wyndham Las Cruces Mesilla Valley
790 Avenida De Mesilla Las Cruces NM
Fully refundableReserve now, pay when you stay
$46 nightly
The price is $55 total per night from Jun 29 to Jun 30
$55 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the conference space and free ...
"Love the nighttime front desk clerk"
Reviewed on Jun 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Dona Ana hotel reviews by fellow wanderers

Ramada Hotel & Conference Center by Wyndham Las Cruces
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Hotel is older. It is going through a remodel so certain things weren't working. AC in main lobby and in rooms was rough. Pool was nice. I didn't see much for breakfast, but I think dining and bar service are down due to renovation. Also be careful of the tub, it was really high up when I tried to step out."
A verified traveler stayed at Ramada Hotel & Conference Center by Wyndham Las Cruces
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