
Deals on vacations and trips to Downtown South San Francisco

Downtown South San Francisco flight + hotel vacation packages
Price found within the past 48 hours. Click for updated prices.

SF Central Hotel
South of Market
Save 100% on your flight
Price was $653, price is now $377 per person
$377
per person
Apr 3 - Apr 7
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
Self parking is available and the hotel's multilingual staff can provide around-the-clock assistance. WiFi in public areas is free. Luggage storage is also provided.

Hotel Zeppelin San Francisco
Union Square
Price was $872, price is now $489 per person
$489
per person
Apr 8 - Apr 14
found 23 hours ago
Roundtrip non-stop flight included
New York (JFK) to San Francisco (SFO)
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. A coffee shop, a lobby fireplace, and dry cleaning are also on offer.

The Westin St. Francis San Francisco on Union Square
Union Square
Save 100% on your flight
Price was $1,081, price is now $631 per person
$631
per person
Mar 14 - Mar 18
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and valet parking. A coffee shop, express check-out, and dry cleaning are also on offer.

Hotel EPIK
Downtown San Francisco
Price was $804, price is now $491 per person
$491
per person
Apr 8 - Apr 14
found 23 hours ago
Roundtrip non-stop flight included
New York (JFK) to San Francisco (SFO)
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the free continental breakfast each morning.

Hotel Riu Plaza Fisherman's Wharf
Fisherman's Wharf
Save 100% on your flight
Price was $688, price is now $428 per person
$428
per person
Apr 9 - Apr 12
found 9 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to San Francisco (SFO)
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the 24-hour gym and free buffet breakfast each morning.
Top Downtown South San Francisco hotels deals

Hotel Riu Plaza Fisherman's Wharf
2500 Mason St San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$142 nightly
The price is $168 total per night
$168 total
Feb 10 - Feb 11
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the 24-hour gym and free buffet breakfast each morning.
Pool
Breakfast included

Hilton San Francisco Financial District
750 Kearny St San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$117 nightly
The price is $137 total per night
$137 total
Jan 23 - Jan 24
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and WiFi in public areas. Self parking, a terrace, and limo/town car service are also offered.
Pet friendly
Restaurant

Fairmont San Francisco
950 Mason Street Atop Nob Hill San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$333 nightly
The price is $391 total per night
$391 total
Jan 25 - Jan 26
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, and valet parking. Relax with a drink at one of the 2 bars/lounges and enjoy the sauna.
Spa
Pet friendly

Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Free Cancellation
$127 nightly
The price is $149 total per night
$149 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a bar/lounge on site, and a 24-hour front desk and laundry facilities are also provided.
Pool
Free WiFi

Hyatt Place San Francisco Downtown
701 3rd St San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$149 nightly
The price is $175 total per night
$175 total
Jan 23 - Jan 24
Total with taxes and fees
A bar/lounge and a 24-hour front desk are featured at this hotel, along with self parking. WiFi in public areas is free. A terrace, dry cleaning, and luggage storage are also on offer.
Pet friendly
Free WiFi

Club Quarters Hotel in San Francisco
424 Clay St San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$130 nightly
The price is $153 total per night
$153 total
Feb 16 - Feb 17
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee shop, a terrace, and limo/town car service are also on offer.
Pet friendly
Free WiFi
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See all available properties in Downtown South San Francisco
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Golden Gate Bridge
Cars trundle across it and ships sail under it, but the best way to experience this iconic bridge is on foot.

Golden Gate Park
This beloved park offers relaxation among trees, flowers and wildlife, right in San Francisco’s backyard.

Pier 39
This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.
Frequently asked questions
Photos of local treasures
Browse Downtown South San Francisco vacation photos for more inspiration


