Explore top 2026 4 Star Hotels in San Ysidro

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Top San Ysidro 4 Star hotels

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
$236 nightly
The price is $274 total per night from May 25 to May 26
$274 total
May 25 - May 26
Total with taxes and fees
This hotel features 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (2,839 reviews)
The Manchester Hyatt always delivers as expected. They have valet and bellhop which is important to me traveling with a special needs child and I need the convenience of having some help moving all of the luggage up to the room and parking the car for us. The room was well appointed and clean. They ...

Reviewed on Apr 25, 2026

Opens in a new windowManchester Grand Hyatt San Diego
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$262 nightly
The price is $303 total per night from May 3 to May 4
$303 total
May 3 - May 4
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
9/10 Wonderful! (3,603 reviews)
The manager, Zoe, when out of her way to make our stay amazing. Excellent customer service across the board… and a great location too!

Reviewed on May 1, 2026

Opens in a new windowHard Rock Hotel San Diego
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $194 total per night from May 25 to May 26
$194 total
May 25 - May 26
Total with taxes and fees
A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi ...
8.4/10 Very Good! (3,504 reviews)
Had a great weekend stay here. Beautiful views and a great location, so close to the airport. Will be coming back soon.

Reviewed on Apr 29, 2026

Opens in a new windowSheraton San Diego Resort
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd San Diego CA
$225 nightly
The price is $259 total per night from May 10 to May 11
$259 total
May 10 - May 11
Total with taxes and fees
This smoke-free hotel features a full-service spa, a marina, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
8.4/10 Very Good! (1,619 reviews)
Every day went there was very polite. It’s great for kids. The pool is open till 10. The slides do close early though at 5 PM I think.

Reviewed on Apr 25, 2026

Opens in a new windowHyatt Regency Mission Bay Spa and Marina
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

4 out of 5
601 Pacific Hwy San Diego CA
Fully refundableReserve now, pay when you stay
$211 nightly
The price is $244 total per night from May 25 to May 26
$244 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, express check-in, and valet ...
9/10 Wonderful! (1,737 reviews)
Parking car cost too high, why is there a fee? The pool room - chlorine smell is strong! Breakfast & reception hour are nice.

Reviewed on Apr 28, 2026

Opens in a new windowEmbassy Suites by Hilton San Diego Bay Downtown
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $211 total per night from May 3 to May 4
$211 total
May 3 - May 4
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public ...
8.4/10 Very Good! (6,134 reviews)
Family short vaca had fun enjoyed the spacious room

Reviewed on Apr 30, 2026

Opens in a new windowWyndham San Diego Bayside
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
$254 nightly
The price is $292 total per night from May 10 to May 11
$292 total
May 10 - May 11
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...
8.8/10 Excellent! (2,558 reviews)
Paradise Point was the perfect resort for our vacation in San Diego. Loved the resort amenities like adults only pool, spa (massage was excellent) multiple pools, access to bay, mini golf and cafe by the water. Rooms are spacious and quiet. My cousin and I were very comfortable and relaxed during ...

Reviewed on Apr 30, 2026

Opens in a new windowParadise Point Resort & Spa
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$249 nightly
The price is $286 total per night from May 4 to May 5
$286 total
May 4 - May 5
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
9.4/10 Exceptional! (1,622 reviews)
Staff were so attentive, helpful, responsive and kind! Lovely stay, well worth it! If you’re hoping for a quiet stay, this isn’t it. Although they do supply ear plugs that helped tremendously. If you’re looking for fun and great people watching, this is the place for you!

Reviewed on Apr 30, 2026

Opens in a new windowLafayette Hotel & Club
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

4 out of 5
675 L St San Diego CA
Fully refundableReserve now, pay when you stay
$208 nightly
The price is $241 total per night from May 25 to May 26
$241 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9.2/10 Wonderful! (2,160 reviews)
The food, drinks, the sixth floor pool area with food and cocktails was absolutely amazing . absolute comfort! The staff in every area of the omni was amazing as well. The ease to Petco was great as we took in a Chicago cubs/Padres 3 game series

Reviewed on Apr 30, 2026

Opens in a new windowOmni San Diego Hotel at the Ballpark
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr San Diego CA
Fully refundableReserve now, pay when you stay
$270 nightly
The price is $313 total per night from May 8 to May 9
$313 total
May 8 - May 9
Total with taxes and fees
A marina, 5 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Bring the family and enjoy the children's pool and kid-friendly dining. ...
9.2/10 Wonderful! (2,104 reviews)
Great stay

Reviewed on Apr 30, 2026

Opens in a new windowMarriott Marquis San Diego Marina
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4 Star Hotels San Ysidro

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in San Ysidro 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in San Ysidro will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in San Ysidro, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent San Ysidro hotel reviews by fellow wanderers