Explore top 2026 4 Star Hotels in East St. Louis
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Top East St. Louis 4 Star hotels
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $158 total per night from Oct 30 to Oct 31
$158 total
Oct 30 - Oct 31
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Nov 1 to Nov 2
$173 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Live by Loews - St.Louis
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $189 total per night from Oct 18 to Oct 19
$189 total
Oct 18 - Oct 19
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
The Westin St. Louis
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $153 total per night from Oct 18 to Oct 19
$153 total
Oct 18 - Oct 19
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$186 nightly
The price is $219 total per night from Nov 1 to Nov 2
$219 total
Nov 1 - Nov 2
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $144 total per night from Oct 12 to Oct 13
$144 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
Marriott St. Louis Grand
800 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $181 total per night from Oct 20 to Oct 21
$181 total
Oct 20 - Oct 21
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Embassy Suites by Hilton St. Louis Downtown
610 N 7th St St. Louis MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $136 total per night from Oct 18 to Oct 19
$136 total
Oct 18 - Oct 19
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-in, and valet ...
9/10 Wonderful! (1,350 reviews)
"Very clean nice rooms. Staff was excellent and friendly. Happy hour was so fun. Great location. Will stay again."
Reviewed on Oct 6, 2026
Hilton St. Louis at the Ballpark
1 S Broadway St. Louis MO
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $175 total per night from Oct 15 to Oct 16
$175 total
Oct 15 - Oct 16
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an indoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $132 total per night from Oct 18 to Oct 19
$132 total
Oct 18 - Oct 19
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.6/10 Excellent! (1,376 reviews)
"It sucks with hidden fees"
Reviewed on Oct 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels East St. Louis
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in East St. Louis 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in East St. Louis will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in East St. Louis, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent East St. Louis hotel reviews by fellow wanderers
Drury Plaza Hotel St. Louis Union Station
5 out of 5
Posted 11 hours ago
Travelocity Verified Review
"Wonderful stay! Everything was clean, and the staff was absolutely amazing. I didn’t catch the manager’s name, but he really impressed me. You could tell his staff genuinely liked and respected him, and it was easy to see why. He was right there working alongside them—even doing the dirty work—not standing back or acting like anything was beneath him. That kind of leadership really stood out to me. Nico brought such great energy and was extremely helpful as well. Honestly, everyone we encountered worked hard, was friendly and polite, and made us feel welcome. Great staff, great leadership, and a wonderful experience. They truly helped make our trip amazing!"
A verified traveler stayed at Drury Plaza Hotel St. Louis Union Station
