Explore top 2026 4 Star Hotels in Defiance
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Top Defiance 4 Star hotels
Hilton St. Louis Frontenac
"Everything was excellent"
Reviewed on May 19, 2026
Ameristar Casino Resort and Spa
"The room was very spacious and the bathroom was also. One of our tv remotes didnʻt work. I wish there was on site laundry and I wish the pool was kid friendly on the weekend at least during the daytime hours, however I understand it is a Casino gaming hotel but I think that would be a great adjustment. ..."
Reviewed on May 19, 2026
DoubleTree by Hilton St. Louis - Westport
"The Doubletree Hotel in St. Louis was one the best hotels I've stayed in. The staff was an absolute joy. The amenities, the rooms cleanest and the bar was great, as well. The restaurant food was excellent.."
Reviewed on May 19, 2026
DoubleTree by Hilton Hotel St. Louis - Chesterfield
"We’re nice hotel just wish the pool was open later instead of 9"
Reviewed on May 17, 2026
The Inn at Elijah McLeans
"We chose this place for location near the train station. The room was clean but is more of a “motel 6” vibe and comfortable level. Mattress was fine but bedding was uncomfortable. No staff just self check in and out. We were riding the Katy Trail and there was outdoor bike racks that were convenient. ..."
Reviewed on May 17, 2026
Landing Apartments - Eureka
'the Ruebling House': Bright, Modern, & Renovated!
4 Star Hotels Defiance
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Defiance 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Defiance will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Defiance, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Defiance hotel reviews by fellow wanderers
Ameristar Casino Resort and Spa
"The room was very spacious and the bathroom was also. One of our tv remotes didnʻt work. I wish there was on site laundry and I wish the pool was kid friendly on the weekend at least during the daytime hours, however I understand it is a Casino gaming hotel but I think that would be a great adjustment. I was surprised there werenʻt more on site restaurants available, and I also wish we had access to all the restaurants because the one we really wanted to try and made reservations for before realizing it was inside the casino. The front desk staff was always amazing and very sweet and helpful! Would definitely stay here again, very convenient location to everything we had planned on this trip!"
