Explore top 2026 4 Star Hotels in Brussels

Name: Historic Main Street Heritage Retreat
Rating: 9.4

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Top Brussels 4 Star hotels

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road St. Louis MO

Fully refundableReserve now, pay when you stay

$118 nightly

$138 total

Jan 30 - Jan 31

Total with taxes and fees

This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

8.4/10 Very Good! (1,066 reviews)

Our check in was flawless as always and the staff was very friendly

Reviewed on Jan 11, 2026

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO

Fully refundableReserve now, pay when you stay

$193 nightly

$226 total

Jan 25 - Jan 26

Total with taxes and fees

This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...

8.4/10 Very Good! (1,012 reviews)

Very clean

Reviewed on Jan 16, 2026

Marriott St. Louis Airport

10700 Pear Tree Lane St. Louis MO

Fully refundableReserve now, pay when you stay

$140 nightly

$167 total

Jan 24 - Jan 25

Total with taxes and fees

This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center, express check-in, and free airport ...

7.8/10 Good! (1,000 reviews)

The staff was great and the hotel was beautiful for location. It looked well maintained.

Reviewed on Jan 11, 2026

DoubleTree by Hilton St. Louis - Westport

1973 Craigshire Rd Maryland Heights MO

Fully refundableReserve now, pay when you stay

$116 nightly

$135 total

Feb 6 - Feb 7

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8/10 Very Good! (1,000 reviews)

Love this hotel

Reviewed on Jan 4, 2026

DoubleTree by Hilton St. Louis Airport

4505 Woodson Road St. Louis MO

$101 nightly

$119 total

Jan 25 - Jan 26

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Bring the family and enjoy the arcade/game room and kid-friendly dining. There's no skimping ...

7.8/10 Good! (875 reviews)

Nice staff

Reviewed on Jan 7, 2026

DoubleTree by Hilton Hotel St. Louis - Chesterfield

16625 Swingley Ridge Rd Chesterfield MO

Fully refundableReserve now, pay when you stay

$122 nightly

$142 total

Feb 20 - Feb 21

Total with taxes and fees

7 indoor tennis courts, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center ...

8.6/10 Excellent! (1,000 reviews)

All the above

Reviewed on Dec 21, 2025

Historic Main Street Heritage Retreat

Saint Charles MO

This apartment features laundry facilities.

9.4/10 Exceptional! (40 reviews)

Welcome email was informative.

Reviewed on Dec 22, 2025

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Beall Mansion An Elegant Bed & Breakfast Inn

407 E. 12th St. Alton IL

This bed & breakfast features free WiFi in public areas, concierge services, and free self parking. Enjoy the 4 hot tubs and free continental breakfast each ...

Excellent bed and breakfast!

Wonderful stay! This home is beautiful. Our hosts Sandy and Jim were gracious and it was a pleasure to be with them for the evening. Highly recommended!

Reviewed on Oct 21, 2024

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4 Star Hotels Brussels

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Brussels 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Brussels will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Brussels, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.