Upstate South Carolina Vacation Packages 2026 from $221

Upstate South Carolina flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Tru By Hilton Charlotte Tyvola I-77

$221

per person

Feb 26 - Mar 1

found 3 hours ago

Roundtrip flight included

Orlando (MCO) to Charlotte (CLT)

This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.

The Horse Shoe Farm

Save 100% on your flight

$1,709

per person

Mar 15 - Mar 22

found 4 hours ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

A full-service spa, an outdoor pool, and a restaurant are all featured at this ranch. Families will appreciate the arcade/game room and onsite laundry facilities. Enjoy the hot tub and free perks like continental breakfast and free self parking.

The Restoration Asheville

Downtown Asheville

$774

per person

Mar 20 - Mar 23

found 11 hours ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

This smoke-free hotel's 3 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. There's fun for all ages with a bowling alley and an arcade/game room, and complimentary bicycles are available on site. Enjoy the a rooftop terrace and free perks like continental breakfast and an area shuttle.

Landing Apartments - University City North

University City

Save 100% on your flight

$335

per person

Feb 26 - Mar 1

found 3 hours ago

Roundtrip flight included

Orlando (MCO) to Charlotte (CLT)

This apartment features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A virtual front desk are provided for your convenience.

Hilton Garden Inn Asheville Downtown

Downtown Asheville

$614

per person

Mar 20 - Mar 23

found 11 hours ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

The hotel's outdoor pool, 24-hour gym, and 2 bars/lounges are among the featured amenities. Enjoy a meal from the restaurant and freebies like WiFi in public areas and an area shuttle. Self parking, a 24-hour business center, and a coffee shop are also offered.

Top Upstate South Carolina hotels deals

Hilton Greenville

45 W Orchard Park Dr Greenville SC

Free Cancellation

Reserve now, pay when you stay

$100 nightly

$110 total

Jan 11 - Jan 12

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, and laundry service. Self parking, a terrace, and a garden are also offered.

Pet friendly

Free WiFi

Homewood Suites by Hilton Greenville Downtown

950 South Main Street Greenville SC

Free Cancellation

Reserve now, pay when you stay

$134 nightly

$147 total

Jan 22 - Jan 23

Total with taxes and fees

This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the free buffet breakfast each morning.

Pool

Breakfast included

Embassy Suites Greenville Golf Resort & Conference Center

670 Verdae Blvd Greenville SC

Free Cancellation

Reserve now, pay when you stay

$104 nightly

$115 total

Jan 18 - Jan 19

Total with taxes and fees

A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy the outdoor pool and free buffet breakfast each morning.

Pool

Breakfast included

Wooded Cottage - 3 Mi to Clemson University

Clemson SC

Get rates

Free WiFi in public areas is available at this cottage.

Kitchen

Pet friendly

Grand Bohemian Lodge Greenville, Autograph Collection

44 EAST CAMPERDOWN WAY Greenville SC

Free Cancellation

Reserve now, pay when you stay

$235 nightly

$259 total

Jan 28 - Jan 29

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free WiFi. Valet parking, a lobby fireplace, and a communal living room are also offered.

Spa

Pet friendly

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

11 Ketron Court Greenville SC

Free Cancellation

Reserve now, pay when you stay

$86 nightly

$94 total

Jan 11 - Jan 12

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free breakfast and free WiFi. Traveling on business? Take advantage of the 24-hour business center and free internet in public areas. A garden, a picnic area, and a computer station are also on offer.

Breakfast included

Pet friendly

Don't see what you're looking for?

See all available properties in Upstate South Carolina

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Clemson University

5/5(410 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

Falls Park on the Reedy

4.5/5(583 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.

Entrance to stadium and tradition. #footballstadiumtours

Memorial Stadium

5/5(129 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.

Frequently asked questions

How much are vacation packages to Upstate South Carolina?

$221 is all you need to spend for an exhilarating break in Upstate South Carolina. Bundle your hotel and flights into a vacation package with Travelocity and watch how the savings start to pile up. With prices this good, you'll want to start packing your suitcase now!

Where can I get the best vacation package deals for Upstate South Carolina?

For an amazing Upstate South Carolina package deal, you can't go past Travelocity. Take your pick of 400 air carriers and 1,000,000 properties worldwide to create your dream escape — the choice is all yours!

Why should I purchase my Upstate South Carolina vacation bundle with Travelocity?

With our Price Match Guarantee, we'll match any better price you can find. Add to that our 24/7 support and top-quality service and the vacation you've been dreaming of is well within reach.

Can I save money on my Upstate South Carolina car rental if I bundle it with a hotel or flight?

You sure can. And our Upstate South Carolina vacation packages are the ideal way to do it. In only a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car then chart your own course. Searching for things to do? Throw some tours or experiences into your package and save on those too.

Which airport is best for Upstate South Carolina?

Upstate South Carolina has two major airports — Greenville-Spartanburg Intl. Airport (GSP) and Asheville Regional Airport (AVL).

What is there to do in Upstate South Carolina?

You'll be happy to know Upstate South Carolina is full to the brim with incredible photo opportunities, however Clemson University and Lake Keowee are right up there with the very best.