Upstate South Carolina Vacation Packages 2026 from $646

Upstate South Carolina flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Smoketree Lodge

$646

per person

Dec 26 - Jan 2

found 17 hours ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

This aparthotel features an indoor pool and a gym. Enjoy the sauna and perks like free self parking and free WiFi. A terrace, limo/town car service, and a garden are also on offer.

The Highlands at Sugar

$1,328

per person

Dec 26 - Jan 2

found 17 hours ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

This apartment features an indoor pool and a gym. There's fun for all ages with a playground and an arcade/game room, and barbecue grills are available on site. Enjoy the hot tub and perks like free self parking and free WiFi.

AEA - Eagles Nest NC

$7,199

per person

Dec 26 - Jan 2

found 17 hours ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

This apartment features a virtual front desk. Take advantage of the free self parking.

The Restoration Asheville

Downtown Asheville

$729

per person

Dec 12 - Dec 15

found 20 hours ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

This smoke-free hotel's 3 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. There's fun for all ages with a bowling alley and an arcade/game room. Enjoy the a rooftop terrace and free perks like continental breakfast and an area shuttle.

The Lodge at Banner Elk

$1,055

per person

Dec 26 - Jan 2

found 17 hours ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

A gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A business center, a lobby fireplace, and a picnic area are also on offer.

Top Upstate South Carolina hotels deals

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

Free Cancellation

Reserve now, pay when you stay

$85 total

per night

Nov 8 - Nov 9

This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

Pool

Breakfast included

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

851 Congaree Rd Greenville SC

Free Cancellation

$110 total

per night

Nov 23 - Nov 24

This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Unwind with a drink at one of the 2 bars/lounges and enjoy free perks like free self parking and an area shuttle.

Pool

Free airport shuttle

Embassy Suites Greenville Golf Resort & Conference Center

670 Verdae Blvd Greenville SC

Free Cancellation

Reserve now, pay when you stay

$111 total

per night

Nov 23 - Nov 24

A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy the outdoor pool and free buffet breakfast each morning.

Pool

Breakfast included

Hyatt Regency Greenville

220 N Main St Greenville SC

$153 total

per night

Nov 23 - Nov 24

This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a seasonal outdoor pool on site, and concierge services and wedding services are also offered.

Pool

Pet friendly

Grand Bohemian Lodge Greenville, Autograph Collection

44 EAST CAMPERDOWN WAY Greenville SC

Free Cancellation

Reserve now, pay when you stay

$397 total

per night

Nov 29 - Nov 30

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A lobby fireplace, a communal living room, and dry cleaning are also on offer.

Spa

Pet friendly

Hilton Greenville

45 W Orchard Park Dr Greenville SC

$95 total

per night

Dec 2 - Dec 3

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, and laundry service. Self parking, a terrace, and a garden are also offered.

Pet friendly

Free WiFi

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

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Frequently asked questions

How much are vacation packages to Upstate South Carolina?

$646 is all you need to spend for an exhilarating break in Upstate South Carolina. Bundle your hotel and flights into a vacation package with Travelocity and watch how the savings start to pile up. With prices this good, you'll want to start packing your suitcase now!

Where can I get the best vacation package deals for Upstate South Carolina?

For an amazing Upstate South Carolina package deal, you can't go past Travelocity. Take your pick of 400 air carriers and 1,000,000 properties worldwide to create your dream escape — the choice is all yours!

Why should I purchase my Upstate South Carolina vacation bundle with Travelocity?

With our Price Match Guarantee, we'll match any better price you can find. Add to that our 24/7 support and top-quality service and the vacation you've been dreaming of is well within reach.

Can I save money on my Upstate South Carolina car rental if I bundle it with a hotel or flight?

You sure can. And our Upstate South Carolina vacation packages are the ideal way to do it. In only a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car then chart your own course. Searching for things to do? Throw some tours or experiences into your package and save on those too.

Which airport is best for Upstate South Carolina?

Upstate South Carolina has two major airports — Greenville-Spartanburg Intl. Airport (GSP) and Asheville Regional Airport (AVL).

What is there to do in Upstate South Carolina?

You'll be happy to know Upstate South Carolina is full to the brim with incredible photo opportunities, however Clemson University and Lake Keowee are right up there with the very best.