Book Hotels in South Sanford, ME

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Top South Sanford hotels

Hampton Inn & Suites Portsmouth Downtown

Hampton Inn & Suites Portsmouth Downtown

3 out of 5
23 Portwalk Pl Portsmouth NH
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $133 total per night from Jan 29 to Jan 30
$133 total
Jan 29 - Jan 30
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. ...
Staff was excellent, went above and beyond!

Reviewed on Jan 4, 2026

Opens in a new windowHampton Inn & Suites Portsmouth Downtown
Cliff House Maine

Cliff House Maine

4.5 out of 5
591 Shore Road Cape Neddick ME
$747 nightly
The price is $814 total per night from Jan 22 to Jan 23
$814 total
Jan 22 - Jan 23
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free resort. Traveling on business? Take advantage of the business center, ...
The room along with the view was spectacular - Beautifully decorated - Clean - Crisp - The Staff - Beyond Helpful!! The location overlooking the Atlantic Ocean even this time of year with the sun and the ocean waves hitting the rocks was like out of a movie!! Their restaurants 5 star in my opinion!! ...

Reviewed on Jan 6, 2026

Opens in a new windowCliff House Maine
AC Hotel by Marriott Portsmouth

AC Hotel by Marriott Portsmouth

3.5 out of 5
299 Vaughn Street Portsmouth NH
Fully refundableReserve now, pay when you stay
$160 nightly
The price is $174 total per night from Jan 18 to Jan 19
$174 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features 2 bars/lounges and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and valet parking. ...
Beautiful hotel in walking distance to everything. Love the rooftop bar and the gym.

Reviewed on Jan 10, 2026

Opens in a new windowAC Hotel by Marriott Portsmouth
Residence Inn by Marriott Portsmouth Downtown/ Waterfront

Residence Inn by Marriott Portsmouth Downtown/ Waterfront

3 out of 5
100 Deer Street Portsmouth NH
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $147 total per night from Jan 25 to Jan 26
$147 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. ...
The breakfast had all kinds of goodies. Oatmeal, with several toppings to choose from. The hot menu seems to change from day to day. We were there for a week, had eggs & bacon one day, then sausage patties and links the next. They surprised me on day 4 by having spinach quiche! Cereals, juice, breads, ...

Reviewed on Jan 7, 2026

Opens in a new windowResidence Inn by Marriott Portsmouth Downtown/ Waterfront
Anchorage Inn and Resort

Anchorage Inn and Resort

3 out of 5
265 Long Beach Avenue York Beach ME
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $108 total per night from Jan 15 to Jan 16
$108 total
Jan 15 - Jan 16
Total with taxes and fees
This hotel features 2 indoor pools, an outdoor pool, and a restaurant. Enjoy the gym and perks like free self parking and free WiFi. Enjoy the hot tub and unwind ...
This place is our favorite place to stay, never had a bad experience staying here.

Reviewed on Jan 10, 2026

Opens in a new windowAnchorage Inn and Resort
Hampton Inn Portsmouth Central

Hampton Inn Portsmouth Central

2.5 out of 5
131 DOW AVENUE Portsmouth NH
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $106 total per night from Jan 21 to Jan 22
$106 total
Jan 21 - Jan 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub and free perks like buffet ...
Excellent breakfast omelettes, nicely crisped bacon, great little lemon-poppy scones!

Reviewed on Jan 11, 2026

Opens in a new windowHampton Inn Portsmouth Central
Hilton Garden Inn Portsmouth Downtown

Hilton Garden Inn Portsmouth Downtown

3 out of 5
100 High St Portsmouth NH
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $120 total per night from Jan 25 to Jan 26
$120 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
The room was really clean. The only negative are the chairs in the rooms are hard as a rock and not comfortable.

Reviewed on Jan 7, 2026

Opens in a new windowHilton Garden Inn Portsmouth Downtown
Old Orchard Beach Inn

Old Orchard Beach Inn

2.5 out of 5
6 Portland Ave Old Orchard Beach ME
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $95 total per night from Jan 16 to Jan 17
$95 total
Jan 16 - Jan 17
Total with taxes and fees
A seasonal outdoor pool, free self parking, and wedding services are featured at this bed & breakfast. WiFi in public areas is free. A garden, a library, and ...
Beautiful quaint hotel. Clean rooms

Reviewed on Jan 3, 2026

Opens in a new windowOld Orchard Beach Inn
Ramada by Wyndham Saco/Old Orchard Beach Area

Ramada by Wyndham Saco/Old Orchard Beach Area

2.5 out of 5
352 North St Saco ME
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $79 total per night from Jan 22 to Jan 23
$79 total
Jan 22 - Jan 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
Al very good

Reviewed on Jan 3, 2026

Opens in a new windowRamada by Wyndham Saco/Old Orchard Beach Area
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in South Sanford?
Family getaways are where treasured memories are made, but traveling with youngsters can be demanding. These kid-friendly South Sanford hotels come with perks designed to keep travelers of all ages comfortable and happy: You're well catered for at Huttopia Southern Maine. It comes with a swimming pool, a playground and a commitment to making families feel at home. Otherwise, spend your nights in South Sanford at Quality Inn. Make the most of complimentary breakfast, pet-friendly facilities and more here.
Where can I find cheap hotels in South Sanford?
At Travelocity you'll find really nice hotels in South Sanford at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near South Sanford rather than in South Sanford. We may find you even better rates, too.
How do I find the best South Sanford hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in South Sanford then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in South Sanford?
The cheapest hotel in South Sanford is $79. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in South Sanford?
There are 3,601 hotels in South Sanford on Travelocity.
What are the best hotels in South Sanford?
South Sanford has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in South Sanford for you!
When is the best time to visit South Sanford?
If you want the joy of a fun-filled trip in peak season, visit South Sanford during January, June and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as April, September and October.
When is the cheapest time to stay in South Sanford?
Based on historic data is usually the cheapest month to visit South Sanford. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in South Sanford?
There are multiple hotels in South Sanford that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to South Sanford. We have plenty of kid-friendly hotels in South Sanford to choose from on Travelocity!
Why book a hotel in South Sanford through Travelocity?
Because we have the top hotels in South Sanford! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in South Sanford on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent South Sanford hotel reviews by fellow wanderers

AC Hotel by Marriott Portsmouth

AC Hotel by Marriott Portsmouth

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Beautiful hotel in walking distance to everything. Love the rooftop bar and the gym. "
A verified traveler stayed at AC Hotel by Marriott Portsmouth
AC Hotel by Marriott Portsmouth

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