Book Hotels in South Sanford, ME
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Top South Sanford hotels

Hampton Inn & Suites Portsmouth Downtown
23 Portwalk Pl Portsmouth NH
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $129 total per night from Dec 7 to Dec 8
$129 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. ...
Clean, comfortable rooms. Great breakfast.
Reviewed on Nov 27, 2025

Cliff House Maine
591 Shore Road Cape Neddick ME
$487 nightly
The price is $531 total per night from Dec 4 to Dec 5
$531 total
Dec 4 - Dec 5
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free resort. Traveling on business? Take advantage of the business center, ...
Amazing view, even for our more basic room.
Reviewed on Nov 25, 2025

Anchorage by the Sea
125 Shore Road Ogunquit ME
$186 nightly
The price is $203 total per night from Dec 14 to Dec 15
$203 total
Dec 14 - Dec 15
Total with taxes and fees
This smoke-free hotel features 2 hot tubs, an indoor pool, and a restaurant. Traveling on business? Take advantage of the free WiFi in public areas and onsite ...
Room was great and resort was nice
Reviewed on Nov 25, 2025

Hampton Inn Portsmouth Central
131 DOW AVENUE Portsmouth NH
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $103 total per night from Dec 19 to Dec 20
$103 total
Dec 19 - Dec 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub and free perks like buffet ...
Clean room and friendly staff.
Reviewed on Nov 23, 2025

Anchorage Inn and Resort
265 Long Beach Avenue York Beach ME
$119 nightly
The price is $130 total per night from Dec 1 to Dec 2
$130 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel features 2 indoor pools, an outdoor pool, and a restaurant. Enjoy the gym and perks like free self parking and free WiFi. Enjoy the hot tub and unwind ...
Great!
Reviewed on Nov 26, 2025

Howard Johnson by Wyndham Portsmouth
383 Woodbury Ave Portsmouth NH
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $93 total per night from Dec 2 to Dec 3
$93 total
Dec 2 - Dec 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Parking was easy. Staff was very friendly. Overall, the room was clean. The bathroom sink drained very slowly. The hot
Reviewed on Nov 21, 2025

Hilton Garden Inn Portsmouth Downtown
100 High St Portsmouth NH
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $124 total per night from Dec 28 to Dec 29
$124 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
Wonderfully friendly staff. Clean rooms, beautiful lobby and PERFECT location!
Reviewed on Nov 15, 2025

Sheraton Portsmouth Harborside Hotel
250 Market St Portsmouth NH
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $156 total per night from Dec 7 to Dec 8
$156 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Great bartender!!!!
Reviewed on Nov 25, 2025

Old Orchard Beach Inn
6 Portland Ave Old Orchard Beach ME
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $111 total per night from Dec 2 to Dec 3
$111 total
Dec 2 - Dec 3
Total with taxes and fees
A seasonal outdoor pool, free self parking, and wedding services are featured at this bed & breakfast. WiFi in public areas is free. A garden, a library, and ...
The room is small but very comfortable.
Reviewed on Nov 3, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent South Sanford hotel reviews by fellow wanderers

Hampton Inn & Suites Portsmouth Downtown
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Clean, comfortable rooms. Great breakfast."
A verified traveler from Dover stayed at Hampton Inn & Suites Portsmouth Downtown
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