Book Hotels in South Sanford, ME
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Top South Sanford hotels

Hampton Inn & Suites Portsmouth Downtown
23 Portwalk Pl Portsmouth NH
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $137 total per night from Nov 23 to Nov 24
$137 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. ...
Excellent all around!
Reviewed on Nov 14, 2025

Cliff House Maine
591 Shore Road Cape Neddick ME
$487 nightly
The price is $531 total per night from Nov 30 to Dec 1
$531 total
Nov 30 - Dec 1
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free resort. Traveling on business? Take advantage of the business center, ...
Perfect views!
Reviewed on Nov 12, 2025

Anchorage by the Sea
125 Shore Road Ogunquit ME
$186 nightly
The price is $203 total per night from Dec 14 to Dec 15
$203 total
Dec 14 - Dec 15
Total with taxes and fees
This smoke-free hotel features 2 hot tubs, an indoor pool, and a restaurant. Traveling on business? Take advantage of the free WiFi in public areas and onsite ...
Great location and views! Nice room and staff, good restaurant on site, wonderful hot tubs and cool decorations for Halloween. Great value.
Reviewed on Nov 1, 2025

Hampton Inn Portsmouth Central
99 Durgin Ln, Portsmouth, NH
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $103 total per night from Nov 30 to Dec 1
$103 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub and free perks like buffet ...
Friendly staff
Reviewed on Nov 12, 2025

Howard Johnson by Wyndham Portsmouth
383 Woodbury Ave Portsmouth NH
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $93 total per night from Nov 18 to Nov 19
$93 total
Nov 18 - Nov 19
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Clean room but I wasnt able to hook up my laptop to the TV to use as a monitor.
Reviewed on Nov 13, 2025

Hilton Garden Inn Portsmouth Downtown
100 High St Portsmouth NH
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $123 total per night from Nov 30 to Dec 1
$123 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
good
Reviewed on Nov 12, 2025

Old Orchard Beach Inn
6 Portland Ave Old Orchard Beach ME
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $104 total per night from Nov 23 to Nov 24
$104 total
Nov 23 - Nov 24
Total with taxes and fees
A seasonal outdoor pool, free self parking, and wedding services are featured at this bed & breakfast. WiFi in public areas is free. A garden, a library, and ...
The room is small but very comfortable.
Reviewed on Nov 3, 2025

Quality Inn
1892 Main Street, Sanford, ME
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $109 total per night from Nov 23 to Nov 24
$109 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. The front desk is ...
The evening desk clerk was wonderful. Room was clean There was a distinct scent of weed in hallways ,
Reviewed on Nov 14, 2025

Ramada by Wyndham Saco/Old Orchard Beach Area
352 North St, Saco, ME
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $86 total per night from Nov 18 to Nov 19
$86 total
Nov 18 - Nov 19
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
Clean room
Reviewed on Nov 11, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent South Sanford hotel reviews by fellow wanderers
Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"The rooms are really spacious, clean and the front desk staff were very welcoming with dinner recommendations "
A verified traveler stayed at Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel
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