Book Hotels in South Sanford, ME

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight
Sep 27 - Sep 28
Tomorrow
Sep 28 - Sep 29
Next weekend
Oct 3 - Oct 5
In two weeks
Oct 10 - Oct 12

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top South Sanford hotels

Cliff House Maine

Cliff House Maine

4.5 out of 5
591 Shore Road, Cape Neddick, ME
$497 nightly
The price is $542 total per night from Oct 28 to Oct 29
$542 total
Oct 28 - Oct 29
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free resort. Traveling on business? Take advantage of the business center, ...
"We were celebrating our 10th Anniversary and we asked about upgrading our room and the front desk representative pleasantly upgraded our stay. The staff around the resort were all friendly and accommodating."

Reviewed on Sep 19, 2025

Opens in a new windowCliff House Maine
Hampton Inn & Suites Portsmouth Downtown

Hampton Inn & Suites Portsmouth Downtown

3 out of 5
23 Portwalk Pl, Portsmouth, NH
Fully refundableReserve now, pay when you stay
$212 nightly
The price is $230 total per night from Oct 19 to Oct 20
$230 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. ...
"No"

Reviewed on Sep 25, 2025

Opens in a new windowHampton Inn & Suites Portsmouth Downtown
Ogunquit - The Milestone

Ogunquit - The Milestone

2 out of 5
687 Main Street, Ogunquit, ME
$99 nightly
The price is $108 total per night from Oct 1 to Oct 2
$108 total
Oct 1 - Oct 2
Total with taxes and fees
This motel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. You'll appreciate ...
"We came to Ogunquit for a Friday afternoon wedding. We were able to access early check in, even though it was a holiday weekend. The staff was very friendly and accommodating, the room was very comfortable and the hotel was located close to many places."

Reviewed on Sep 23, 2025

Opens in a new windowOgunquit - The Milestone
Anchorage Inn and Resort

Anchorage Inn and Resort

3 out of 5
265 Long Beach Avenue, York Beach, ME
$119 nightly
The price is $130 total per night from Oct 19 to Oct 20
$130 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features 2 indoor pools, an outdoor pool, and a restaurant. Enjoy the gym and perks like free self parking and free WiFi. Enjoy the hot tub and unwind ...
"Great resort, excellent location, you can hear the waves At your door. Friendly staff, pool areas are inviting. Stayed many times and will return."

Reviewed on Sep 24, 2025

Opens in a new windowAnchorage Inn and Resort
Anchor Inn and Cottages Wells-Ogunquit

Anchor Inn and Cottages Wells-Ogunquit

2.5 out of 5
424 Post Rd, Wells, ME
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $104 total per night from Oct 1 to Oct 2
$104 total
Oct 1 - Oct 2
Total with taxes and fees
A seasonal outdoor pool, free self parking, and barbecue grills are featured at this motel. WiFi in public areas is free. A garden and a picnic area are also ...
"It was very well kept. The only problem finger prints on the ceiling lol. I will be staying there with family in the future."

Reviewed on Sep 23, 2025

Opens in a new windowAnchor Inn and Cottages Wells-Ogunquit
Hilton Garden Inn Portsmouth Downtown

Hilton Garden Inn Portsmouth Downtown

3 out of 5
100 High St, Portsmouth, NH
$199 nightly
The price is $216 total per night from Oct 19 to Oct 20
$216 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
"The room was nice and even more spacious for a typical 2 bed room and a family of 4. However, the walls were very thin. While the woman next door were just up late and chatting, it was as if they were in the same room."

Reviewed on Sep 18, 2025

Opens in a new windowHilton Garden Inn Portsmouth Downtown
Old Orchard Beach Inn

Old Orchard Beach Inn

2.5 out of 5
6 Portland Ave, Old Orchard Beach, ME
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $131 total per night from Sep 28 to Sep 29
$131 total
Sep 28 - Sep 29
Total with taxes and fees
A seasonal outdoor pool, free self parking, and wedding services are featured at this bed & breakfast. WiFi in public areas is free. A garden, a library, and ...
"The Old Orchard Beach Inn was an absolute dream! We arrived at Midnight, took us a little bit to find our room, however, what a gem! Woke up to an apple tree outside our window and a view of the beach! The comfy bed and pillows made it the best sleep of our trip. The bathroom was so clean - definitely ..."

Reviewed on Sep 21, 2025

Opens in a new windowOld Orchard Beach Inn
Sea Latch Inn

Sea Latch Inn

2 out of 5
277 Long Beach Avenue, Rte. 1A, York Beach, ME
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $106 total per night from Oct 26 to Oct 27
$106 total
Oct 26 - Oct 27
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. A garden, a picnic area, and luggage ...
"I loved that they’re right across the street from the ocean and I can see the ocean from my room."

Reviewed on Sep 21, 2025

Opens in a new windowSea Latch Inn
Ramada by Wyndham Saco/Old Orchard Beach Area

Ramada by Wyndham Saco/Old Orchard Beach Area

2.5 out of 5
352 North St, Saco, ME
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $110 total per night from Oct 19 to Oct 20
$110 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business ...
"Clean room, friendly staff"

Reviewed on Sep 25, 2025

Opens in a new windowRamada by Wyndham Saco/Old Orchard Beach Area
Don't see what you're looking for?
See all available properties in South Sanford
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in South Sanford?
Family getaways are where treasured memories are made, but traveling with youngsters can be demanding. These kid-friendly South Sanford hotels come with perks designed to keep travelers of all ages comfortable and happy: You're well catered for at Huttopia Southern Maine. It comes with a swimming pool, a playground and a commitment to making families feel at home. Otherwise, spend your nights in South Sanford at Quality Inn. Make the most of complimentary breakfast, pet-friendly facilities and more here.
Where can I find cheap hotels in South Sanford?
At Travelocity you'll find really nice hotels in South Sanford at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near South Sanford rather than in South Sanford. We may find you even better rates, too.
How do I find the best South Sanford hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in South Sanford then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in South Sanford?
The cheapest hotel in South Sanford is $104. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in South Sanford?
There are 3,833 hotels in South Sanford on Travelocity.
What are the best hotels in South Sanford?
South Sanford has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in South Sanford for you!
When is the best time to visit South Sanford?
If you want the joy of a fun-filled trip in peak season, visit South Sanford during January, June and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as April, September and October.
When is the cheapest time to stay in South Sanford?
Based on historic data is usually the cheapest month to visit South Sanford. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in South Sanford?
There are multiple hotels in South Sanford that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to South Sanford. We have plenty of kid-friendly hotels in South Sanford to choose from on Travelocity!
Why book a hotel in South Sanford through Travelocity?
Because we have the top hotels in South Sanford! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in South Sanford on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent South Sanford hotel reviews by fellow wanderers

Port Inn and Suites Portsmouth, an Ascend Collection Hotel

Port Inn and Suites Portsmouth, an Ascend Collection Hotel

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Amazing "
A verified traveler stayed at Port Inn and Suites Portsmouth, an Ascend Collection Hotel
Port Inn and Suites Portsmouth, an Ascend Collection Hotel
Explore More Ways to Travel with Travelocity

Explore More Ways to Travel with Travelocity