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Top hotels in Sanibel Isles

Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
$224 nightly
The price is $250 total per night from Nov 1 to Nov 2
$250 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink ...
"Overall good. Nice room. When we arrived the key to our room wouldn’t work. They gave us a different room and the keys wouldn’t work for that either. So we had to prop the door open if we left the room until the engineer arrived the next morning at 8:30. I finally called at 8:50 so we could leave ..."

Reviewed on Oct 30, 2026

Opens in a new windowSanibel Island Beach Resort
La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

3 out of 5
28600 Trails Edge Blvd Bonita Springs FL
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $115 total per night from Nov 1 to Nov 2
$115 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Everyone that works here is very kind and looking to make your stay comfortable. Heather goes above and beyond to help in all situations she’s great!"

Reviewed on Oct 29, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Bonita Springs Naples N.
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $149 total per night from Nov 2 to Nov 3
$149 total
Nov 2 - Nov 3
Total with taxes and fees
This smoke-free hotel features 3 restaurants, 3 beach bars, and 6 bars/lounges. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Enjoy ...
"The Staff was very helpful and nice. The beach view was beautiful. Watched dolphins from our balcony."

Reviewed on Oct 31, 2026

Opens in a new windowLani Kai Beachfront Resort
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $266 total per night from Nov 15 to Nov 16
$266 total
Nov 15 - Nov 16
Total with taxes and fees
A full-service spa, 4 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy the 5 outdoor tennis courts and indoor pool, and unwind ...
"Beautiful resort. The fitness center was well equipped and clean. The pools were wonderful. Dolphins were observed feeding just off the dock. The walking paths are nice. Even off season there were plenty of staff in restaurant and at the pool cafe. Great view off the balcony of our room. Be prepared ..."

Reviewed on Oct 30, 2026

Opens in a new windowMarriott Sanibel Harbour Resort & Spa
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

3 out of 5
1051 5th St Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $164 total per night from Nov 2 to Nov 3
$164 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features 2 outdoor pools, a restaurant, and a bar/lounge. Relax with a drink at the poolside bar and enjoy perks like free self parking and free WiFi. ...
"Great room right next to the pool"

Reviewed on Oct 30, 2026

Opens in a new windowThe Lighthouse Resort Inn & Suites
Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral

2 out of 5
4760 S Cleveland Ave Fort Myers FL
Fully refundable
$52 nightly
The price is $57 total per night from Nov 22 to Nov 23
$57 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the laundry ...
"Clean outdated rooms. Wasn't impressed with breakfast bar."

Reviewed on Oct 30, 2026

Opens in a new windowQuality Inn Fort Myers Cape Coral
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$210 nightly
The price is $234 total per night from Nov 1 to Nov 2
$234 total
Nov 1 - Nov 2
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Opens in a new windowMargaritaville Beach Resort Fort Myers
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E Cape Coral FL
Fully refundable
$100 nightly
The price is $112 total per night from Nov 3 to Nov 4
$112 total
Nov 3 - Nov 4
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Opens in a new windowHoliday Inn Express Cape Coral-Fort Myers Area by IHG
Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs

4 out of 5
11800 Coconut Cove Drive Bonita Springs FL
$226 nightly
The price is $252 total per night from Nov 16 to Nov 17
$252 total
Nov 16 - Nov 17
Total with taxes and fees
3 outdoor pools, a lazy river, and a gym are all featured at this smoke-free hotel. There's fun for all ages with a children's pool and an arcade/game room, ...
Opens in a new windowHyatt Vacation Club at Coconut Cove, Bonita Springs
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Sanibel Isles Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Sanibel Isles area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Sanibel Isles to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Sanibel Isles are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Sanibel Isles hotel reviews by fellow wanderers

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

4 out of 5
Posted 6 hours ago
Travelocity Verified Review
"The Staff was very helpful and nice. The beach view was beautiful. Watched dolphins from our balcony."
A verified traveler stayed at Lani Kai Beachfront Resort
Lani Kai Beachfront Resort

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