Explore 174 Luxury Hotels in San Diego

Name: Manchester Grand Hyatt San Diego
Price range: $320 total

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Best Luxury Hotels in San Diego

Ocean Villa Inn

5142 West Point Loma Blvd San Diego CA

$152 nightly

$171 total

Oct 1 - Oct 2

Total with taxes and fees

A seasonal outdoor pool, self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A garden, luggage storage, and concierge ...

8/10 Very Good! (1,393 reviews)

"The only thing good about this property was the view the room smelled of dog dirty and rundown for sure. Spent over 200 night and have pre-booked another words stuck with this property. If you have animals great place to stay if you don’t mind the shape of the property otherwise I suggest to find ..."

Reviewed on Sep 29, 2026

Best Western Seven Seas

411 Hotel Circle South San Diego CA

$89 nightly

$102 total

Oct 1 - Oct 2

Total with taxes and fees

2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...

8/10 Very Good! (3,943 reviews)

"Worth the cost, would definitely return"

Reviewed on Sep 30, 2026

The US Grant, a Luxury Collection Hotel, San Diego

326 Broadway San Diego CA

Fully refundableReserve now, pay when you stay

$237 nightly

$276 total

Oct 25 - Oct 26

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...

Fairmont Grand Del Mar

5300 Grand Del Mar Court San Diego CA

Fully refundableReserve now, pay when you stay

$769 nightly

$884 total

Oct 18 - Oct 19

Total with taxes and fees

This luxury hotel features a golf course, a full-service spa, and 6 restaurants. There's fun for all ages with a children's club and a children's pool, and babysitting ...

Westgate Hotel

1055 Second Ave San Diego CA

Fully refundableReserve now, pay when you stay

$193 nightly

$223 total

Oct 25 - Oct 26

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, ...

Alma San Diego Downtown, a Tribute Portfolio Hotel

1047 5th Ave San Diego CA

Fully refundableReserve now, pay when you stay

$241 nightly

$279 total

Oct 25 - Oct 26

Total with taxes and fees

This boutique hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...

The Sofia Hotel

150 W Broadway San Diego CA

Fully refundableReserve now, pay when you stay

$181 nightly

$210 total

Oct 25 - Oct 26

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

Manchester Grand Hyatt San Diego

1 Market Pl San Diego CA

Fully refundableReserve now, pay when you stay

$276 nightly

$320 total

Oct 25 - Oct 26

Total with taxes and fees

This smoke-free hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in San Diego

Hilton San Diego Gaslamp Quarter

401 K St San Diego CA

$236 nightly

$274 total

Oct 25 - Oct 26

Total with taxes and fees

9/10 Wonderful! (548 reviews)

5 star hotels in San Diego

Pendry San Diego

550 J Street San Diego CA

$342 nightly

$397 total

Oct 25 - Oct 26

Total with taxes and fees

9.4/10 Exceptional! (1,001 reviews)

San Diego Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the San Diego luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in San Diego to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in San Diego will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in San Diego, and plan your next opulent escape.

San Diego hotels essential information

Accommodation	7,101 hotels
Lowest Price	$102
Highest Price	$884
Popular hotels	The US Grant, a Luxury Collection Hotel, San Diego, Fairmont Grand Del Mar, Westgate Hotel, Alma San Diego Downtown, a Tribute Portfolio Hotel, The Sofia Hotel, Ocean Villa Inn, Best Western Seven Seas, Manchester Grand Hyatt San Diego