Explore 23 Luxury Hotels in Mission Valley

Name: Sheraton Mission Valley San Diego Hotel
Price range: $206 total

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Best Luxury Hotels in Mission Valley

Kings Inn San Diego

1333 Hotel Cir S San Diego CA

Fully refundableReserve now, pay when you stay

$104 nightly

$119 total

Sep 29 - Sep 30

Total with taxes and fees

This Art Deco hotel includes 2 restaurants, an outdoor pool, and a hot tub. Enjoy the gym and perks like free WiFi. A bar/lounge, a 24-hour front desk, and a ...

8.8/10 Excellent! (3,751 reviews)

Reviewed on Sep 16, 2026

Hampton Inn San Diego/Mission Valley

2151 Hotel Circle South San Diego CA

Fully refundableReserve now, pay when you stay

$130 nightly

$150 total

Oct 4 - Oct 5

Total with taxes and fees

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...

8.6/10 Excellent! (1,748 reviews)

"Unfortunately I wasn’t even able to stay at the hotel due to their system being updated which I wasn’t completely aware of it. So when I arrive to check in they had no record. The guy at the front desk couldn’t even give me a room because he doesn’t have access to it. At this point I was super tired ..."

Reviewed on Sep 16, 2026

Days Inn by Wyndham San Diego Hotel Circle

543 Hotel Circle S San Diego CA

Fully refundableReserve now, pay when you stay

$84 nightly

$97 total

Sep 29 - Sep 30

Total with taxes and fees

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...

8/10 Very Good! (3,077 reviews)

"The room was nice and clean."

Reviewed on Sep 16, 2026

Motel 6 San Diego, CA - Hotel Circle - Mission Valley

2424 Hotel Circle North San Diego CA

Fully refundableReserve now, pay when you stay

$78 nightly

$90 total

Oct 1 - Oct 2

Total with taxes and fees

An outdoor pool, self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. Staff at the 24-hour front desk can provide around-the-clock ...

6.6/10 (1,587 reviews)

"Room was filthy,"

Reviewed on Sep 16, 2026

Best Western Seven Seas

411 Hotel Circle South San Diego CA

Fully refundableReserve now, pay when you stay

$85 nightly

$97 total

Sep 20 - Sep 21

Total with taxes and fees

2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...

The Atwood Hotel San Diego - SeaWorld/Zoo

1201 Hotel Circle South San Diego CA

Fully refundableReserve now, pay when you stay

$100 nightly

$115 total

Oct 15 - Oct 16

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the hot tub and perks like free WiFi. A coffee shop, a snack bar/deli, and a picnic ...

Super 8 by Wyndham San Diego Hotel Circle

445 Hotel Cir S San Diego CA

Fully refundableReserve now, pay when you stay

$78 nightly

$90 total

Oct 18 - Oct 19

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast and free WiFi. Business travelers can take advantage of the business center. Self ...

Sheraton Mission Valley San Diego Hotel

1433 Camino Del Rio S San Diego CA

Fully refundableReserve now, pay when you stay

$179 nightly

$206 total

Sep 30 - Oct 1

Total with taxes and fees

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's ...

Don't see what you're looking for?

See all available properties in Mission Valley

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Mission Valley

Marriott Marquis San Diego Marina

333 W Harbor Dr San Diego CA

$312 nightly

$361 total

Sep 30 - Oct 1

Total with taxes and fees

5 star hotels in Mission Valley

Fairmont Grand Del Mar

5300 Grand Del Mar Court San Diego CA

$789 nightly

$907 total

Oct 18 - Oct 19

Total with taxes and fees

9.6/10 Exceptional! (1,000 reviews)

Mission Valley Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Mission Valley luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Mission Valley to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Mission Valley will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Mission Valley, and plan your next opulent escape.

Mission Valley hotels essential information

Accommodation	8,987 hotels
Lowest Price	$90
Highest Price	$907
Popular hotels	Best Western Seven Seas, Kings Inn San Diego, Days Inn by Wyndham San Diego Hotel Circle, The Atwood Hotel San Diego - SeaWorld/Zoo, Super 8 by Wyndham San Diego Hotel Circle, Motel 6 San Diego, CA - Hotel Circle - Mission Valley, Sheraton Mission Valley San Diego Hotel, Hampton Inn San Diego/Mission Valley

Popular Luxury Stays in Mission Valley

Recent Mission Valley Hotel Reviews By Fellow Wanderers

Days Inn by Wyndham San Diego Hotel Circle

5 out of 5

Posted less than an hour ago

Travelocity Verified Review

"The room was nice and clean."

A verified traveler stayed at Days Inn by Wyndham San Diego Hotel Circle

Kings Inn San Diego

5 out of 5

Posted 3 hours ago

Travelocity Verified Review

"I am so happy that we chose to stay at The Kings Inn. If I'm being honest, the Waffle King drew me in. I'm a sucker for kitsch and character, and that's exactly what we got. Is it the fanciest hotel on the block? Certainly not. But we couldn't have cared less. The room was clean, the staff was friendly, and the pool was to die for. When you're traveling with a toddler who goes to bed at 8 pm, staying in a hotel can mean that you end up matching bedtimes. Luckily, the pool was open until 10 and was only a few steps from our room. Our monitor had perfect range, and we could have reached the door in seconds, so we felt perfectly comfortable having a late-night swim. There was a collection of community pool toys, and our son had a blast playing with the dump truck, buckets, and noodles. We ate at both restaurants and enjoyed both of the meals we had there. Everything about this experience was perfection."

A verified traveler stayed at Kings Inn San Diego

Crowne Plaza San Diego - Mission Valley by IHG

4 out of 5

Posted 6 hours ago

Travelocity Verified Review

"The staff were outstanding but hotel is a bit dated.It may have been because being on the top floor that shower took a few minutes to warm up and the little snack bar was embarrassing especially compared with some of their other locations.Nothing that would keep me from visiting them again."

A verified traveler stayed at Crowne Plaza San Diego - Mission Valley by IHG