Find a Hotel in Matlacha Isles

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Top hotels in Matlacha Isles

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

4 out of 5
275 Estero Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
$266 nightly
The price is $297 total per night from Dec 9 to Dec 10
$297 total
Dec 9 - Dec 10
Total with taxes and fees
A marina, 3 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy the gym and free buffet breakfast each morning. Enjoy the hot ...
Will be coming again!

Reviewed on Nov 2, 2025

Opens in a new windowPink Shell Beach Resort and Marina
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr, Sanibel, FL
Fully refundableReserve now, pay when you stay
$228 nightly
The price is $251 total per night from Nov 13 to Nov 14
$251 total
Nov 13 - Nov 14
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink ...
👌

Reviewed on Nov 2, 2025

Opens in a new windowSanibel Island Beach Resort
DiamondHead Beach Resort

DiamondHead Beach Resort

3.5 out of 5
2000 Estero Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
$211 nightly
The price is $236 total per night from Dec 9 to Dec 10
$236 total
Dec 9 - Dec 10
Total with taxes and fees
This smoke-free resort features 2 hot tubs, an outdoor pool, and a restaurant. Dine at the beachfront restaurant and relax with beach umbrellas. Enjoy the gym ...
Awesome stay

Reviewed on Nov 3, 2025

Opens in a new windowDiamondHead Beach Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street, Fort Myers Beach, FL
$204 nightly
The price is $228 total per night from Nov 17 to Nov 18
$228 total
Nov 17 - Nov 18
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Relax with a drink at one of the 4 bars/lounges and get perks ...
Balcony nice and resort great. Pool and beach

Reviewed on Nov 3, 2025

Opens in a new windowMargaritaville Beach Resort Fort Myers
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
$176 nightly
The price is $197 total per night from Nov 12 to Nov 13
$197 total
Nov 12 - Nov 13
Total with taxes and fees
This hotel features 2 beach bars, a bar/lounge, and a restaurant. Enjoy the outdoor pool and perks like free WiFi. There's a poolside bar on site, and a 24-hour ...
Nice place to stay

Reviewed on Nov 6, 2025

Opens in a new windowLani Kai Beachfront Resort
Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops

4 out of 5
13051 Bell Tower Drive, Fort Myers, FL
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $136 total per night from Dec 7 to Dec 8
$136 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, ...
My room was very clean and the staff was extremely helpful and friendly.

Reviewed on Nov 2, 2025

Opens in a new windowDoubletree by Hilton Fort Myers at Bell Tower Shops
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3 out of 5
12600 University Dr, Fort Myers, FL
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $124 total per night from Nov 30 to Dec 1
$124 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Room was comfortable, neat and clean.

Reviewed on Nov 3, 2025

Opens in a new windowHilton Garden Inn Ft Myers
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr, Fort Myers, FL
Fully refundableReserve now, pay when you stay
$221 nightly
The price is $247 total per night from Nov 30 to Dec 1
$247 total
Nov 30 - Dec 1
Total with taxes and fees
A full-service spa, 4 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy the 5 outdoor tennis courts and indoor pool, and unwind ...
The staff was so welcoming and kind. Upon arrival, Frank welcomed me warmly, and upon departure, Nelson was equally kind. The front desk staff and restaurant personnel were wonderful as was the food I enjoyed there. It was a relaxing week at the hotel and its beautiful setting on Sanibel.

Reviewed on Oct 31, 2025

Opens in a new windowMarriott Sanibel Harbour Resort & Spa
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave, Fort Myers, FL
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $77 total per night from Nov 16 to Nov 17
$77 total
Nov 16 - Nov 17
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
The staff have all been great. The room is roomie, clean and beds are comfortable

Reviewed on Nov 5, 2025

Opens in a new windowBaymont by Wyndham Fort Myers Central
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Matlacha Isles Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Matlacha Isles area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Matlacha Isles to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Matlacha Isles are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Matlacha Isles hotel reviews by fellow wanderers

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

5 out of 5
Posted 3 days ago
Travelocity Verified Review
" Nice place to stay "
A verified traveler stayed at Lani Kai Beachfront Resort
Lani Kai Beachfront Resort

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