Book Hotels in East Cape Girardeau, IL
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Top East Cape Girardeau hotels

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest
Jonesboro IL
A hot tub is featured at this cabin, along with a garden and barbecue grills.
This was our second stay at Docs Cabin and it was just as perfect as the first! We plan to be back!
Reviewed on Dec 17, 2025

Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $88 total per night from Jan 22 to Jan 23
$88 total
Jan 22 - Jan 23
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Room was spotless, staff was SO kind. 5 day trip, stayed in 4 different hotels & this one was BY FAR the nicest. Breakfast was fabulous. 10 out of 10 recommend!!
Reviewed on Jan 15, 2026

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Jan 25 to Jan 26
$102 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The room was clean and I enjoyed my stay. I would book there more in the future trips to come.
Reviewed on Jan 17, 2026

The Riverview
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $118 total per night from Jan 26 to Jan 27
$118 total
Jan 26 - Jan 27
Total with taxes and fees
This hotel features a casino and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference space. ...
Yes
Reviewed on Jan 16, 2026

Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Jan 25 to Jan 26
$102 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Loved the happy hour, and pet friendly & shower.
Reviewed on Jan 13, 2026

Courtyard by Marriott Cape Girardeau Downtown
400 Broadway St. Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $152 total per night from Jan 30 to Jan 31
$152 total
Jan 30 - Jan 31
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Nice place
Reviewed on Jan 10, 2026

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $80 total per night from Jan 25 to Jan 26
$80 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
The room was spacious, wonderful king size bed and the room was spotless.st
Reviewed on Jan 13, 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $86 total per night from Jan 22 to Jan 23
$86 total
Jan 22 - Jan 23
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Great staff. Friendly. Very clean and neat place.
Reviewed on Jan 15, 2026

Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd Cape Girardeau MO
Fully refundable
$78 nightly
The price is $93 total per night from Feb 8 to Feb 9
$93 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self parking, ...
We enjoyed the cleanliness of the room, the Christmas decorations, and the location.
Reviewed on Jan 4, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent East Cape Girardeau hotel reviews by fellow wanderers

Drury Plaza Hotel Cape Girardeau Conference Center
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"The room was clean and I enjoyed my stay. I would book there more in the future trips to come. "
A verified traveler stayed at Drury Plaza Hotel Cape Girardeau Conference Center
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