Book Hotels in East Cape Girardeau, IL

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top East Cape Girardeau hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $113 total per night from Mar 15 to Mar 16
$113 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Clean room , nice staff

Reviewed on Mar 6, 2026

Opens in a new windowDrury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $85 total per night from Mar 12 to Mar 13
$85 total
Mar 12 - Mar 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
This was our first stay at a Drury hotel

Reviewed on Mar 5, 2026

Opens in a new windowDrury Inn & Suites Jackson MO
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St. Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $142 total per night from Mar 19 to Mar 20
$142 total
Mar 19 - Mar 20
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The bed was so comfortable. Everything was very clean. Location was right in downtown so it was very convenient.

Reviewed on Mar 6, 2026

Opens in a new windowCourtyard by Marriott Cape Girardeau Downtown
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $104 total per night from Mar 15 to Mar 16
$104 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a casino and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference space. ...
Room was perfect

Reviewed on Mar 6, 2026

Opens in a new windowThe Riverview
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Mar 15 to Mar 16
$102 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Great as all Drury’s

Reviewed on Mar 4, 2026

Opens in a new windowDrury Inn & Suites Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street Cape Girardeau MO
Fully refundable
$95 nightly
The price is $107 total per night from Mar 15 to Mar 16
$107 total
Mar 15 - Mar 16
Total with taxes and fees
A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
Clean room staff is very nice parking it great

Reviewed on Mar 6, 2026

Opens in a new windowHoliday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $91 total per night from Mar 11 to Mar 12
$91 total
Mar 11 - Mar 12
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Clean rooms. Friendly staff.

Reviewed on Mar 6, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Mar 15 to Mar 16
$81 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
Yes to all the above.

Reviewed on Mar 2, 2026

Opens in a new windowPear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 out of 5
485 S Mount Auburn Rd Cape Girardeau MO
Fully refundable
$80 nightly
The price is $96 total per night from Mar 15 to Mar 16
$96 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self parking, ...
Pet friendly but charge a ridiculous amount of $75 Per pet!! Didn’t disclose untill check on.

Reviewed on Mar 5, 2026

Opens in a new windowCandlewood Suites Cape Girardeau by IHG
Don't see what you're looking for?
See all available properties in East Cape Girardeau
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in East Cape Girardeau?
From cool amenities to more room to move, kid-friendly hotels come with features that can help turn a good family vacation into an amazing one. These East Cape Girardeau properties make getting away with little ones easy: Beautiful Cabin Retreat will help make your next trip the best one yet. It offers plenty of nice little touches, such as a king bed and animal viewing activities. Beautiful newly renovated farm house overlooking 5 acre lake. New Rates * is another top pick. After a big day of exploring, come home to your comfy room and perks like a playground and animal viewing activities.
Where can I find cheap hotels in East Cape Girardeau?
At Travelocity you'll find really nice hotels in East Cape Girardeau at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near East Cape Girardeau rather than in East Cape Girardeau. We may find you even better rates, too.
How do I find the best East Cape Girardeau hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in East Cape Girardeau then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in East Cape Girardeau?
The cheapest hotel in East Cape Girardeau is $81. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in East Cape Girardeau?
There are 98 hotels in East Cape Girardeau on Travelocity.
What are the best hotels in East Cape Girardeau?
East Cape Girardeau has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in East Cape Girardeau for you!
When is the best time to visit East Cape Girardeau?
If you want the joy of a fun-filled trip in peak season, visit East Cape Girardeau during May, June and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in East Cape Girardeau?
Based on historic data is usually the cheapest month to visit East Cape Girardeau. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in East Cape Girardeau?
There are multiple hotels in East Cape Girardeau that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to East Cape Girardeau. We have plenty of kid-friendly hotels in East Cape Girardeau to choose from on Travelocity!
Why book a hotel in East Cape Girardeau through Travelocity?
Because we have the top hotels in East Cape Girardeau! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in East Cape Girardeau on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent East Cape Girardeau hotel reviews by fellow wanderers

The Riverview

The Riverview

5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Room was perfect"
A verified traveler stayed at The Riverview
The Riverview

Explore More Ways to Travel with Travelocity