Book Hotels in Murphysboro, IL

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Top Murphysboro hotels

The Lab! Come stay in our brand new space.

The Lab! Come stay in our brand new space.

Murphysboro
$192 nightly
The price is $203 total per night from Sep 29 to Sep 30
$203 total
Sep 29 - Sep 30
Total with taxes and fees
Stay at this apartment in Murphysboro. Popular attractions Town Square and General John A. Logan Museum are located nearby.
"We had a great time here! We were visiting our college daughter and loved having two bedrooms and making some home cooked meals! Honestly wish we would’ve had more time. The main street area looked like a great place to explore!"

Reviewed on Sep 8, 2025

Opens in a new windowThe Lab! Come stay in our brand new space.
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 out of 5
120 MUDDY MONSTER ROAD, Murphysboro, IL
Fully refundable
$129 nightly
The price is $143 total per night from Oct 12 to Oct 13
$143 total
Oct 12 - Oct 13
Total with taxes and fees
A restaurant and an indoor pool are featured at this hotel. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies ...
Arkansas
"Great hotel. No complaints."

Reviewed on Sep 21, 2025

Opens in a new windowHoliday Inn Express & Suites Murphysboro - Carbondale by IHG
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St, Marion, IL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $78 total per night from Oct 5 to Oct 6
$78 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"I’d give this hotel 10 stars! Great service, food, drinks, cheerful staff, comfortable room. Highly recommend!"

Reviewed on Sep 24, 2025

Opens in a new windowDrury Inn & Suites Marion
Best Western Marion Hotel

Best Western Marion Hotel

2.5 out of 5
400 Comfort Dr, Marion, IL
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $96 total per night from Oct 6 to Oct 7
$96 total
Oct 6 - Oct 7
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Check in was smooth and convenient. Staff were very pleasant and professional,"

Reviewed on Sep 26, 2025

Opens in a new windowBest Western Marion Hotel
Baymont by Wyndham Marion

Baymont by Wyndham Marion

2.5 out of 5
2608 W Main St, Marion, IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $113 total per night from Sep 30 to Oct 1
$113 total
Sep 30 - Oct 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Wonderful"

Reviewed on Sep 28, 2025

Opens in a new windowBaymont by Wyndham Marion
Comfort Inn & Suites Carbondale University Area

Comfort Inn & Suites Carbondale University Area

2.5 out of 5
2400 Reed Station Parkway, Carbondale, IL
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $97 total per night from Oct 12 to Oct 13
$97 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Staff were very helpful and friendly. Nice quiet area."

Reviewed on Sep 27, 2025

Opens in a new windowComfort Inn & Suites Carbondale University Area
Super 8 by Wyndham Carbondale

Super 8 by Wyndham Carbondale

2 out of 5
1180 E Main St, Carbondale, IL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $75 total per night from Sep 29 to Sep 30
$75 total
Sep 29 - Sep 30
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Multilingual staff at the 24-hour front desk ...
"It was rightly priced."

Reviewed on Sep 25, 2025

Opens in a new windowSuper 8 by Wyndham Carbondale
University Inn of Carbondale

University Inn of Carbondale

2.5 out of 5
2400 W Main St, Carbondale, IL
$55 nightly
The price is $63 total per night from Sep 29 to Sep 30
$63 total
Sep 29 - Sep 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Cheap place to stay but beware….
"You could tell this building used to be something else cause it is definitely aged and not in a cute charming kind of way. They have tried their best to make it look historical. I saw signs for guest laundry and fitness center but they didn’t actually exist. My room was next door to the bar that ..."

Reviewed on Sep 23, 2025

Opens in a new windowUniversity Inn of Carbondale
Lakefront, dog-friendly cabin with covered porch & firepit - near wine tasting

Lakefront, dog-friendly cabin with covered porch & firepit - near wine tasting

Murphysboro
This cabin features laundry facilities.
Get rates
Opens in a new windowLakefront, dog-friendly cabin with covered porch & firepit - near wine tasting
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Murphysboro Hotel & Travel Guide\n

Book ahead of time as there aren't many accommodation options within an easy drive of Murphysboro's heart.

The Americas Best Value Inn-Murphysboro/Carbondale is the nearest Travelocity-listed room to the downtown area of Murphysboro and is located a simple and brief drive away.

10 miles (17 kilometers) outside of the main part of Murphysboro, you will find the Holiday Inn Carbondale-Conference Center. The Hampton Inn Carbondale is situated 10 miles (16 kilometers) away. Other possible places to rest your head are the Days Inn & Suites Carbondale and the Best Western Saluki Inn.

Do you want to make your way a little bit further afield? Southern Illinois offers lots of attractions worth seeing. Familiarize yourself with Southern Illinois's farms and don't forget to relish the region's rural landscapes, rolling hills and prairies. In this fascinating part of United States of America adventurous visitors may also try their hand at rock climbing, hiking and abseiling.

Marion is 20 miles (36 kilometers) to the east of Murphysboro and is where you'll find Kokopelli Golf Club and Marion Carnegie Library. Next time you spend a night or two in Marion, check out the Fairfield Inn and Suites by Marriott Marion and Comfort Suites Marion. Alternatively, you could stay in Benton, 30 miles (45 kilometers) northeast of Murphysboro, where you can choose between the Country Hearth Inn and Econo Lodge Benton. Should you choose to stay in Benton, be sure to explore the Franklin County Fairgrounds and Benton City Park.

Just because you're on a break, does not mean you can't fuel your obsession with a day watching sports. Discover Rent One Park 20 miles (34 kilometers) to the east of Murphysboro. Travelocity customers that are thinking of locating a hotel in the area, make a reservation in the Holiday Inn Express Hotel & Suites Marion Northeast or Comfort Inn Marion.

When you are traveling through Williamson County Regional Airport and would like to find a Travelocity-listed hotel in the area, check out Hampton Inn Marion or Marion Airport Inn & Suites.

Frequently asked questions

What are the top kid-friendly hotels in Murphysboro?
Family vacations are where you make the best memories, but it's no secret that traveling with young ones can be demanding. These kid-friendly Murphysboro hotels offer perks designed to keep adventurers of all ages relaxed and happy: You'll be well looked after at Holiday Inn Express & Suites Murphysboro - Carbondale, an IHG Hotel. It comes with complimentary breakfast, a swimming pool and a flair for making families feel welcome. The Lab! Come stay in our brand new space. is also a hit with families. After a long day of sightseeing, return to your comfortable room and amenities like a king bed and pet-friendly facilities.
Where can I find cheap hotels in Murphysboro?
At Travelocity you'll find really nice hotels in Murphysboro at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Murphysboro rather than in Murphysboro. We may find you even better rates, too.
How do I find the best Murphysboro hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Murphysboro then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Murphysboro?
The cheapest hotel in Murphysboro is $63. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Murphysboro?
There are 317 hotels in Murphysboro on Travelocity.
What are the best hotels in Murphysboro?
Murphysboro has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Murphysboro for you!
When is the best time to visit Murphysboro?
If you want the joy of a fun-filled trip in peak season, visit Murphysboro during March, June and November. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, September and October.
When is the cheapest time to stay in Murphysboro?
Based on historic data is usually the cheapest month to visit Murphysboro. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Murphysboro?
There are multiple hotels in Murphysboro that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Murphysboro. We have plenty of kid-friendly hotels in Murphysboro to choose from on Travelocity!
Why book a hotel in Murphysboro through Travelocity?
Because we have the top hotels in Murphysboro! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Murphysboro on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Murphysboro hotel reviews by fellow wanderers

Baymont by Wyndham Marion

Baymont by Wyndham Marion

5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Wonderful "
A verified traveler stayed at Baymont by Wyndham Marion
Baymont by Wyndham Marion
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