Find a Hotel in Cherokee Seneca

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top hotels in Cherokee Seneca

Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street Louisville KY
Fully refundableReserve now, pay when you stay
$175 nightly
The price is $206 total per night from Jun 21 to Jun 22
$206 total
Jun 21 - Jun 22
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
"Todo bueno"

Reviewed on Jun 3, 2026

Opens in a new windowOmni Louisville Hotel
Derby City Gaming & Hotel -  A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

4 out of 5
4520 Poplar Level Rd Louisville KY
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $133 total per night from Jun 7 to Jun 8
$133 total
Jun 7 - Jun 8
Total with taxes and fees
This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
"Great Price Clean and close to downtown"

Reviewed on Jun 3, 2026

Opens in a new windowDerby City Gaming & Hotel - A Churchill Downs Property
The Brown Hotel

The Brown Hotel

4.5 out of 5
335 W Broadway Louisville KY
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $192 total per night from Jun 28 to Jun 29
$192 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
"Our room was comfortable. The only thing to me that lacked was that the TV was too small. It had a nice shower and comfortable bed. I did love the historic atmosphere of the hotel—almost like stepping back in time! It was also convenient to several nice restaurants. Great breakfast we had at the ..."

Reviewed on Jun 3, 2026

Opens in a new windowThe Brown Hotel
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

3 out of 5
635 W Market St Louisville KY
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $126 total per night from Jun 21 to Jun 22
$126 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Staff was great, room was clean. Breakfast was good. Parking was easy"

Reviewed on May 31, 2026

Opens in a new windowHomewood Suites by Hilton Louisville Downtown, KY
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $134 total per night from Jul 3 to Jul 4
$134 total
Jul 3 - Jul 4
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Super clean, awesome facility with very cool restaurants/bars, convenient to downtown and traveling."

Reviewed on Jun 3, 2026

Opens in a new windowGalt House Hotel Trademark Collection by Wyndham
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4 out of 5
501 South Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $124 total per night from Jun 14 to Jun 15
$124 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and a roundtrip airport shuttle. ...
"Everything was perfect but parking lot around the hotel. It confused the lot signs and my car towed a way and got back midnight before we checked out. Law, law it's not very convenient for the tourists at all."

Reviewed on Jun 3, 2026

Opens in a new windowEmbassy Suites Louisville Downtown
Crowne Plaza Louisville Airport Expo Ctr by IHG

Crowne Plaza Louisville Airport Expo Ctr by IHG

3.5 out of 5
830 Phillips Lane Louisville KY
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $97 total per night from Jul 1 to Jul 2
$97 total
Jul 1 - Jul 2
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Great location"

Reviewed on Jun 3, 2026

Opens in a new windowCrowne Plaza Louisville Airport Expo Ctr by IHG
Holiday Inn Louisville Downtown by IHG

Holiday Inn Louisville Downtown by IHG

3 out of 5
101 W. Muhammad Ali Blvd Louisville KY
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $81 total per night from Jun 29 to Jun 30
$81 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. WiFi in public areas is free. Valet parking, a 24-hour business center, and a library are ...
"Good hotel, $36dollar valet is a Lil steep"

Reviewed on Jun 2, 2026

Opens in a new windowHoliday Inn Louisville Downtown by IHG
Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $61 total per night from Jun 10 to Jun 11
$61 total
Jun 10 - Jun 11
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"No microwave in the rooms. But for the price of the rooms, it is worth it"

Reviewed on Jun 3, 2026

Opens in a new windowRadisson Hotel Louisville North
Don't see what you're looking for?
See all available properties in Cherokee Seneca
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cherokee Seneca Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Cherokee Seneca area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Cherokee Seneca to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Cherokee Seneca are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Cherokee Seneca hotel reviews by fellow wanderers