Book Hotels in Carlisle, IA
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Top Carlisle hotels

Des Lux Hotel
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $178 total per night from Jun 4 to Jun 5
$178 total
Jun 4 - Jun 5
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
"Minimal hot options, but multiple to-go options for breakfast! Room was clean and staff was helpful with parking tips!"
Reviewed on Jun 1, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St Des Moines IA
$144 nightly
The price is $161 total per night from Jun 14 to Jun 15
$161 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
"Beautiful lobby. The building has kept much of it's old character and charm. Staff were extremely nice! Gym is very clean and updated. Only thing I would ask for is better condiments for starbuck's coffee in the room. Please stop those packets containing the sweet and lo, powdered creamer etc... ..."
Reviewed on Jun 1, 2026

Home2 Suites by Hilton Des Moines at Drake University
2650 University Ave. Des Moines IA
$106 nightly
The price is $118 total per night from Jun 14 to Jun 15
$118 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Very nice room! The breakfast wasn't the best."
Reviewed on Jun 2, 2026

Drury Inn & Suites West Des Moines
5505 Mills Civic Pkwy West Des Moines IA
$93 nightly
The price is $104 total per night from Jun 7 to Jun 8
$104 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Great experience! Everything is so clean, staff members are super friendly, the hot breakfast is great. Will definitely stay here again."
Reviewed on Jun 1, 2026

Fairfield Inn and Suites by Marriott Des Moines West
7225 Vista Dr West Des Moines IA
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $98 total per night from Jun 7 to Jun 8
$98 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"The night clerk was very welcoming and friendly. The room was quiet, clean and well maintained. Breakfast was hot and delicious with a good variety."
Reviewed on Jun 1, 2026

Stoney Creek Hotel Des Moines - Johnston
5291 Stoney Creek Court Johnston IA
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $122 total per night from Jun 8 to Jun 9
$122 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"Our room door would stick and was hard to open when we tried to go in and out. We had a chair in our room that was broken and I stopped at the front desk to let them know and they said it would get taken care of but no one came to give us a chair we could sit in. There was a sign saying they were ..."
Reviewed on May 30, 2026

Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $85 total per night from Jun 7 to Jun 8
$85 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"All over five star hotel facilities and maintenance."
Reviewed on Jun 1, 2026

Motel 6 West Des Moines, IA
7655 Office Plaza Dr N West Des Moines IA
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $61 total per night from Jun 7 to Jun 8
$61 total
Jun 7 - Jun 8
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace, a snack bar/deli, and laundry facilities are also on ...
"No microwave. Noisy air conditioners. The room was clean."
Reviewed on Jun 1, 2026

Sonesta Essential Des Moines
4755 Merle Hay Road Des Moines IA
$71 nightly
The price is $79 total per night from Jun 8 to Jun 9
$79 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. If you want to take your pet along, this ...
"Breakfast and most of the staff was great"
Reviewed on Jun 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Carlisle hotel reviews by fellow wanderers

Home2 Suites by Hilton Des Moines at Drake University
4 out of 5
Posted less than an hour ago
Travelocity Verified Review
"Very nice room! The breakfast wasn't the best."
A verified traveler stayed at Home2 Suites by Hilton Des Moines at Drake University
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