Book Hotels in Carlisle, IA

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Carlisle hotels

Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St, Des Moines, IA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $189 total per night from Oct 26 to Oct 27
$189 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
"Decided to do something different besides stay one of the big chain hotels. Hotel was very clean, staff was very nice, hotel had a very cozy feel. Room was pleasantly large and very comfortable. Was there for work but stopped at their bar when I got back because it looks so inviting."

Reviewed on Oct 16, 2025

Opens in a new windowDes Lux Hotel
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St, Des Moines, IA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $155 total per night from Nov 2 to Nov 3
$155 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. Valet parking, a business center, and a coffee shop are also ...
"One of my favorite places to stay. The room is clean and comfy always. Wonderful atmosphere."

Reviewed on Oct 14, 2025

Opens in a new windowHotel Fort Des Moines, Curio Collection by Hilton
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave., Des Moines, IA
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $118 total per night from Oct 26 to Oct 27
$118 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"The property was clean and the staff was friendly and helpful. The shower gel and conditioner were empty."

Reviewed on Oct 18, 2025

Opens in a new windowHome2 Suites by Hilton Des Moines at Drake University
Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West

2.5 out of 5
7225 Vista Dr, West Des Moines, IA
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $103 total per night from Oct 26 to Oct 27
$103 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Very comfortable bed, breakfast boil in bag food, not awful. Easy to get back on I 80."

Reviewed on Oct 20, 2025

Opens in a new windowFairfield Inn and Suites by Marriott Des Moines West
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court, Johnston, IA
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $122 total per night from Nov 2 to Nov 3
$122 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"Clean rooms. Pool was great but a little chilly. Staff were prompt."

Reviewed on Oct 18, 2025

Opens in a new windowStoney Creek Hotel Des Moines - Johnston
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave, Des Moines, IA
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $83 total per night from Oct 23 to Oct 24
$83 total
Oct 23 - Oct 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Would have like some different meat for breakfast, like bacon, or sausage. Not just biscuits and sausage."

Reviewed on Oct 18, 2025

Opens in a new windowDays Inn & Suites by Wyndham Des Moines Airport
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N, West Des Moines, IA
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $62 total per night from Nov 4 to Nov 5
$62 total
Nov 4 - Nov 5
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace, a snack bar/deli, and laundry facilities are also on ...
"The room each huge but it was clean and I got a good sleep there. Worth it for the price."

Reviewed on Oct 12, 2025

Opens in a new windowMotel 6 West Des Moines, IA
Sonesta Essential Des Moines

Sonesta Essential Des Moines

2 out of 5
4755 Merle Hay Road, Des Moines, IA
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $71 total per night from Oct 29 to Oct 30
$71 total
Oct 29 - Oct 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. If you want to take your pet along, this ...
"It was a good hotel for a cheap one. Only issue was the bathroom was so small I had to stand in tub to shut the door to use the toilet. And the gentleman that was at the desk when I checked out was just dirty and unsanitary"

Reviewed on Oct 17, 2025

Opens in a new windowSonesta Essential Des Moines
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd, Urbandale, IA
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $79 total per night from Oct 26 to Oct 27
$79 total
Oct 26 - Oct 27
Total with taxes and fees
A water park and a restaurant are featured at this smoke-free hotel. There's fun for all ages with a children's pool and a waterslide, and families will appreciate ...
"Pool"

Reviewed on Oct 13, 2025

Opens in a new windowRamada Tropics Resort & Conf Center by Wyndham Des Moines
Don't see what you're looking for?
See all available properties in Carlisle
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Carlisle?
Family getaways are where wonderful memories are made, but it's no secret that traveling with children can be tricky. These kid-friendly Carlisle hotels come with perks designed to keep travelers of all ages relaxed and happy: Country Inn & Suites by Radisson, Indianola, IA will help make your adventure the best one yet. It features plenty of nice touches, such as a swimming pool and complimentary breakfast. Alternatively, spend your Carlisle trip at Quality Inn Indianola. Make the most of a swimming pool, complimentary breakfast and more here.
Where can I find cheap hotels in Carlisle?
At Travelocity you'll find really nice hotels in Carlisle at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Carlisle rather than in Carlisle. We may find you even better rates, too.
How do I find the best Carlisle hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Carlisle then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Carlisle?
The cheapest hotel in Carlisle is $62. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Carlisle?
There are 772 hotels in Carlisle on Travelocity.
What are the best hotels in Carlisle?
Carlisle has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Carlisle for you!
When is the best time to visit Carlisle?
If you want the joy of a fun-filled trip in peak season, visit Carlisle during April, June and November. If you'd prefer the peace of off-season, book a stay during quieter months, such as March, August and December.
When is the cheapest time to stay in Carlisle?
Based on historic data is usually the cheapest month to visit Carlisle. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Carlisle?
There are multiple hotels in Carlisle that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Carlisle. We have plenty of kid-friendly hotels in Carlisle to choose from on Travelocity!
Why book a hotel in Carlisle through Travelocity?
Because we have the top hotels in Carlisle! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Carlisle on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Carlisle hotel reviews by fellow wanderers

Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Very comfortable bed, breakfast boil in bag food, not awful. Easy to get back on I 80."
A verified traveler stayed at Fairfield Inn and Suites by Marriott Des Moines West
Fairfield Inn and Suites by Marriott Des Moines West

Explore More Ways to Travel with Travelocity