Book Hotels in Carlisle, IA
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Top Carlisle hotels

Des Lux Hotel
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $178 total per night from Jul 1 to Jul 2
$178 total
Jul 1 - Jul 2
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
"Great staff all the way around, wonderful morning breakfast served with a selection and plenty of room to dine. The hotel bar was excellent along with the lobby very well decorated and comfortable."
Reviewed on Jun 25, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $146 total per night from Jul 3 to Jul 4
$146 total
Jul 3 - Jul 4
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
"In our room, the smoke detector flashed brightly all night long which was of course only noticeable with the lights out. The handle on the shower door was wobbly and should have been noticed by cleaning staff. The room design was odd. There was a Keurig-style coffee maker in the room which was snugged ..."
Reviewed on Jun 27, 2026

Drury Inn & Suites West Des Moines
5505 Mills Civic Pkwy West Des Moines IA
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Jul 5 to Jul 6
$112 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Very clean room and super friendly staff. The dinner and breakfast were a great addition to our stay. Great location for your cross country trip."
Reviewed on Jun 27, 2026

Home2 Suites by Hilton Des Moines at Drake University
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $118 total per night from Jul 1 to Jul 2
$118 total
Jul 1 - Jul 2
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"The location of the hotel was perfect, easy and free parking. Nearby to restaurants and coffee shops. The room was comfy and a nice size. Very clean. The staff was very friendly and accessible. I would stay again."
Reviewed on Jun 23, 2026

Fairfield Inn and Suites by Marriott Des Moines West
7225 Vista Dr West Des Moines IA
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Jul 5 to Jul 6
$114 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"The breakfast was great! I wish they had some fresh fruit at the buffet though. Our lock on our door did not work. My husband had to do something with it every time we left."
Reviewed on Jun 27, 2026

Fairfield Inn & Suites by Marriott Des Moines Downtown
207 Crocker Street Des Moines IA
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $103 total per night from Jul 5 to Jul 6
$103 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
"We arrived after 1am and unfortunately Hotels.com only allows to book based on date, meaning because it was after midnight, we technically couldn't check-in til 3pm and it was 1am. Fortunately, the front desk worked with us and found an open room and accommodated our night stay. This was during the ..."
Reviewed on Jun 24, 2026

Stoney Creek Hotel Des Moines - Johnston
5291 Stoney Creek Court Johnston IA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Jun 29 to Jun 30
$109 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"Always a wonderful stay, great staff ."
Reviewed on Jun 26, 2026

Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $83 total per night from Jun 30 to Jul 1
$83 total
Jun 30 - Jul 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Yes"
Reviewed on Jun 26, 2026

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
5000 Merle Hay Rd Urbandale IA
$76 nightly
The price is $85 total per night from Jun 29 to Jun 30
$85 total
Jun 29 - Jun 30
Total with taxes and fees
A water park and a restaurant are featured at this smoke-free hotel. There's fun for all ages with a children's pool and a waterslide, and families will appreciate ...
"I thought the property was disgusting. Stained carpet. Left over food by the pool left out all night. While eating in the restaurant a mouse ran by us into the kitchen. The floor in the shower in my room was so slick I had to put a towel down so i didnt fall. We were told by the manager of the restaurant ..."
Reviewed on Jun 26, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Carlisle hotel reviews by fellow wanderers

Fairfield Inn and Suites by Marriott Des Moines West
5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"The hotel lobby was clean, updated, and smelled great. The room was clean, had been updated fairly recently, but had a few flaws here and there. Nothing major. The breakfast had a lot of choices and it was kept up well. (I do wish hotels would offer almond milk for those of us who can’t drink dairy milk.) In our room you could hear a little highway noise, so I put the fan on “constant” mode and it drowned it out pretty well. Overall we were very happy with our stay here, and we feel like it was a great deal for the reasonable price."
A verified traveler stayed at Fairfield Inn and Suites by Marriott Des Moines West
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