Book Hotels in Carlisle, IA

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Carlisle hotels

Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $200 total per night from Apr 29 to Apr 30
$200 total
Apr 29 - Apr 30
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
Room was large and comfortable, great for a relaxing stay. Breakfast was reasonable and long hours were convenient. Would gladly stay again.

Reviewed on Apr 26, 2026

Opens in a new windowDes Lux Hotel
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $146 total per night from May 24 to May 25
$146 total
May 24 - May 25
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
The hotel is beautiful and I had the best night sleep.

Reviewed on Apr 25, 2026

Opens in a new windowHotel Fort Des Moines, Curio Collection by Hilton
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from May 17 to May 18
$111 total
May 17 - May 18
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A business ...
Breakfast was good, the usual waffles, scrambled eggs , etc. Room was clean, bed comfortable. Only negative was shower was cramped.

Reviewed on Apr 27, 2026

Opens in a new windowWildwood Lodge
Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines

3 out of 5
5505 Mills Civic Pkwy West Des Moines IA
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from May 3 to May 4
$112 total
May 3 - May 4
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Elevator down 😣 Too many people to feel comfortable getting food/beverages Parking was ridiculous. Loved the other locations we have stayed. We wouldn’t stay here again.

Reviewed on Apr 26, 2026

Opens in a new windowDrury Inn & Suites West Des Moines
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from May 3 to May 4
$109 total
May 3 - May 4
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Generally, a good property; however, half of the rooms front a very busy and noisy road. As a result, we didn’t get much sleep awakening to sirens, party goers and a lot of ruckus.

Reviewed on Apr 26, 2026

Opens in a new windowHome2 Suites by Hilton Des Moines at Drake University
La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

3 out of 5
2402 Se Tones Dr Ankeny IA
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $88 total per night from Apr 30 to May 1
$88 total
Apr 30 - May 1
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
We stayed two nights for a tournament and it was quiet and clean . A manger did come up to second floor about 1020pm to quiet down some older baseball boys .no issues at all.

Reviewed on Apr 26, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court Johnston IA
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $122 total per night from Apr 28 to Apr 29
$122 total
Apr 28 - Apr 29
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
Room was clean. Breakfast was excellent!

Reviewed on Apr 26, 2026

Opens in a new windowStoney Creek Hotel Des Moines - Johnston
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $80 total per night from Apr 30 to May 1
$80 total
Apr 30 - May 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Front desk employees were very courteous. Rooms were nice, carpet is very out dated and shower was very yellow, but clean so. But I was on first floor people above me were going until 1:40 at night, after 3 hours of loud banding and what sounding like them dropping stuff I had had enough, called ...

Reviewed on Apr 27, 2026

Opens in a new windowDays Inn & Suites by Wyndham Des Moines Airport
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N West Des Moines IA
Fully refundableReserve now, pay when you stay
$51 nightly
The price is $57 total per night from Apr 29 to Apr 30
$57 total
Apr 29 - Apr 30
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace, a snack bar/deli, and laundry facilities are also on ...
It was as good as you should expect for the price. The floor had a significant soft spot which messed up the flooring a bit. There was a mystery substance splattered across the wall next to the bed and there was something that had been spilled in the fridge. The parts that matter most to me were ...

Reviewed on Apr 26, 2026

Opens in a new windowMotel 6 West Des Moines, IA
Don't see what you're looking for?
See all available properties in Carlisle
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Carlisle?
Family getaways are where wonderful memories are made, but it's no secret that traveling with children can be tricky. These kid-friendly Carlisle hotels come with perks designed to keep travelers of all ages relaxed and happy: Country Inn & Suites by Radisson, Indianola, IA will help make your adventure the best one yet. It features plenty of nice touches, such as a swimming pool and complimentary breakfast. Alternatively, spend your Carlisle trip at Quality Inn Indianola. Make the most of a swimming pool, complimentary breakfast and more here.
Where can I find cheap hotels in Carlisle?
At Travelocity you'll find really nice hotels in Carlisle at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Carlisle rather than in Carlisle. We may find you even better rates, too.
How do I find the best Carlisle hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Carlisle then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Carlisle?
The cheapest hotel in Carlisle is $57. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Carlisle?
There are 843 hotels in Carlisle on Travelocity.
What are the best hotels in Carlisle?
Carlisle has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Carlisle for you!
When is the best time to visit Carlisle?
If you want the joy of a fun-filled trip in peak season, visit Carlisle during April, June and November. If you'd prefer the peace of off-season, book a stay during quieter months, such as March, August and December.
When is the cheapest time to stay in Carlisle?
Based on historic data is usually the cheapest month to visit Carlisle. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Carlisle?
There are multiple hotels in Carlisle that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Carlisle. We have plenty of kid-friendly hotels in Carlisle to choose from on Travelocity!
Why book a hotel in Carlisle through Travelocity?
Because we have the top hotels in Carlisle! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Carlisle on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Carlisle hotel reviews by fellow wanderers

Wildwood Lodge

Wildwood Lodge

5 out of 5
Posted 5 hours ago
Travelocity Verified Review
"Breakfast was good, the usual waffles, scrambled eggs , etc. Room was clean, bed comfortable. Only negative was shower was cramped."
A verified traveler stayed at Wildwood Lodge
Wildwood Lodge

Explore More Ways to Travel with Travelocity