Explore top 2026 5 Star Hotels in Central United States
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Top Central United States 5 Star hotels
Four Seasons Hotel Chicago
120 East Delaware Place Chicago IL
Fully refundableReserve now, pay when you stay
$530 nightly
The price is $630 total per night from Aug 30 to Aug 31
$630 total
Aug 30 - Aug 31
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
The Roosevelt New Orleans, A Waldorf Astoria Hotel
130 Roosevelt Way New Orleans LA
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $194 total per night from Aug 16 to Aug 17
$194 total
Aug 16 - Aug 17
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Trump International Hotel & Tower Chicago
401 N Wabash Ave Chicago IL
Fully refundableReserve now, pay when you stay
$469 nightly
The price is $557 total per night from Aug 16 to Aug 17
$557 total
Aug 16 - Aug 17
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...
Thompson Dallas, by Hyatt
205 North Akard Street Dallas TX
Fully refundableReserve now, pay when you stay
$287 nightly
The price is $336 total per night from Aug 16 to Aug 17
$336 total
Aug 16 - Aug 17
Total with taxes and fees
A full-service spa, 3 restaurants, and a hot tub are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas, ...
9/10 Wonderful! (540 reviews)
"Absolutely loved my stay at the Thompson!! Will definitely be back!!"
Reviewed on Aug 6, 2026
Thompson San Antonio - Riverwalk, by Hyatt
115 Lexington Avenue San Antonio TX
Fully refundableReserve now, pay when you stay
$207 nightly
The price is $244 total per night from Aug 16 to Aug 17
$244 total
Aug 16 - Aug 17
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public ...
The Langham, Chicago
330 North Wabash Avenue Chicago IL
Fully refundableReserve now, pay when you stay
$531 nightly
The price is $631 total per night from Aug 30 to Aug 31
$631 total
Aug 30 - Aug 31
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
9.8/10 Exceptional! (1,003 reviews)
"Excellent hotel in the heart of Chicago on the river. The hotel staff are fabulous! We stayed on the club level and liked it very much. The club room has beverages and food items all day. The view over and down the river is spectacular. Highly recommend the hotel."
Reviewed on Aug 3, 2026
Hilton Anatole
2201 N Stemmons Freeway Dallas TX
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $233 total per night from Aug 29 to Aug 30
$233 total
Aug 29 - Aug 30
Total with taxes and fees
This smoke-free resort features free water park access, a full-service spa, and 4 restaurants. There's fun for all ages with a lazy river and a waterslide, and ...
8.6/10 Excellent! (1,976 reviews)
"Check in took almost an hour but everything else was great, our kids loved the pool and the outdoor games near it"
Reviewed on Aug 6, 2026
1 Hotel Nashville
710 Demonbreun St Nashville TN
Fully refundableReserve now, pay when you stay
$254 nightly
The price is $299 total per night from Aug 23 to Aug 24
$299 total
Aug 23 - Aug 24
Total with taxes and fees
A full-service spa, 2 restaurants, and A 24-hour gym are all featured at this smoke-free hotel. Relax with a drink at one of the 2 bars/lounges and get perks ...
9.4/10 Exceptional! (1,003 reviews)
"The room was incredible, the staff were very professional and friendly. It is a gorgeous spot, very central, and I would recommend it to anyone visiting Nashville. A+"
Reviewed on Aug 5, 2026
The Joseph, a Luxury Collection Hotel, Nashville
401 KOREAN VETERANS BOULEVARD Nashville TN
Fully refundableReserve now, pay when you stay
$294 nightly
The price is $345 total per night from Aug 30 to Aug 31
$345 total
Aug 30 - Aug 31
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the laundry service, conference ...
Conrad Nashville
1620 West End Avenue Nashville TN
Fully refundableReserve now, pay when you stay
$283 nightly
The price is $333 total per night from Aug 16 to Aug 17
$333 total
Aug 16 - Aug 17
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Relax with a drink at the bar/lounge and enjoy perks like free WiFi. There's ...
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Central United States Resorts & 5 Star Hotels
Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Central United States to make sure your trip is as extravagantly comfortable as you expect.
Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!
Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.
For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Central United States 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.
Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Central United States before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.
Recent Central United States hotel reviews by fellow wanderers
The Chicago Hotel Collection Ambassador Gold Coast
5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Clean room and great staff"
A verified traveler stayed at The Chicago Hotel Collection Ambassador Gold Coast
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