Explore top 2026 4 Star Hotels in Greenville - Spartanburg

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Top Greenville - Spartanburg 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$306 nightly
The price is $336 total per night from Apr 27 to Apr 28
$336 total
Apr 27 - Apr 28
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.6/10 Exceptional! (470 reviews)
The property was excellently maintained!

Reviewed on Apr 2, 2026

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
$209 nightly
The price is $230 total per night from Apr 26 to Apr 27
$230 total
Apr 26 - Apr 27
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. ...
9.8/10 Exceptional! (690 reviews)
Always a great time at Hotel Hartness with service, cleanliness and attention to detail. The grounds are exceptional as well

Reviewed on Apr 6, 2026

Opens in a new windowHotel Hartness
Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa

4 out of 5
101 Falls Park Dr Greenville SC
$105 nightly
The price is $115 total per night from May 4 to May 5
$115 total
May 4 - May 5
Total with taxes and fees
A 24-hour gym, self parking, and laundry facilities are featured at this apartment. Express check-in and express check-out are also provided.
9.2/10 Wonderful! (809 reviews)
This is a reasonable and clean space. 1 TV in the livingroom is disappointing if you have multiple ages and family members. Gym is impossible to find without asking for help. Lack of parking availability is a big issue. The parking lot is shared with many businesses and also becomes a paid parking ...

Reviewed on Apr 6, 2026

Opens in a new windowMint House Greenville Downtown by Kasa
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St Greenville SC
Fully refundableReserve now, pay when you stay
$209 nightly
The price is $230 total per night from May 3 to May 4
$230 total
May 3 - May 4
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...
9.2/10 Wonderful! (1,002 reviews)
Wonderful location for downtown walks

Reviewed on Apr 5, 2026

Opens in a new windowThe Westin Poinsett Greenville
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E Greenville SC
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $139 total per night from Apr 19 to Apr 20
$139 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-in, ...
8.6/10 Excellent! (636 reviews)
Clean rooms, great atmosphere

Reviewed on Mar 29, 2026

Opens in a new windowGreenville Marriott
The Station by Compo Hotels

The Station by Compo Hotels

4 out of 5
745 Old Buncombe Rd Travelers Rest SC
$284 nightly
The price is $313 total per night from Apr 8 to Apr 9
$313 total
Apr 8 - Apr 9
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Barbecue grills are provided for your convenience.
10/10 Exceptional! (19 reviews)
Swamp rabbit trail and restaurants very close

Reviewed on Apr 2, 2026

Opens in a new windowThe Station by Compo Hotels
Hotel Domestique

Hotel Domestique

4 out of 5
10 Road of Vines Travelers Rest SC
$429 nightly
The price is $472 total per night from May 7 to May 8
$472 total
May 7 - May 8
Total with taxes and fees
This hotel features a restaurant, an outdoor tennis court, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like cooked-to-order breakfast and ...
Opens in a new windowHotel Domestique
Landing Apartments Greer - Sugar Creek

Landing Apartments Greer - Sugar Creek

4 out of 5
3000 Daventry Cir Greer SC
This apartment features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self ...
Opens in a new windowLanding Apartments Greer - Sugar Creek
Doubletree By Hilton Greenville Airport

Doubletree By Hilton Greenville Airport

4 out of 5
125 The Parkway Greer SC
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $143 total per night from Apr 16 to Apr 17
$143 total
Apr 16 - Apr 17
Total with taxes and fees
A 24-hour gym is available at this hotel. Take advantage of the free self parking.
10/10 Exceptional! (2 reviews)
This work trip was last minute and no hotels were available. This one popped up and I was nervous bc I had never seen it before. That’s because it had only been open 4 days! I couldn’t believe my luck. It was perfect! Perfect food! Perfect hospitality! Perfect room!

Reviewed on Mar 23, 2026

Opens in a new windowDoubletree By Hilton Greenville Airport
Landing Apartments - Lyman

Landing Apartments - Lyman

4 out of 5
610 Universal Drive Lyman SC
This aparthotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Opens in a new windowLanding Apartments - Lyman
Don't see what you're looking for?
See all available properties in Greenville - Spartanburg
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Greenville - Spartanburg

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Greenville - Spartanburg 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Greenville - Spartanburg will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Greenville - Spartanburg, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Greenville - Spartanburg hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity