Explore top 2025 4 Star Hotels in Greenville - Spartanburg

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Top Greenville - Spartanburg 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY, Greenville, SC
Fully refundableReserve now, pay when you stay
$267 nightly
The price is $294 total per night from Sep 28 to Sep 29
$294 total
Sep 28 - Sep 29
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
Grand Bohemian Lodge Greenville, Autograph Collection
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $197 total per night from Sep 7 to Sep 8
$197 total
Sep 7 - Sep 8
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...
The Westin Poinsett Greenville
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E, Greenville, SC
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $145 total per night from Sep 11 to Sep 12
$145 total
Sep 11 - Sep 12
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-in, ...
Greenville Marriott
Mint House Greenville - Downtown

Mint House Greenville - Downtown

4 out of 5
101 Falls Park Dr, Greenville, SC
$122 nightly
The price is $134 total per night from Sep 7 to Sep 8
$134 total
Sep 7 - Sep 8
Total with taxes and fees
A 24-hour gym is featured at this apartment, along with express check-in and express check-out. Laundry facilities are provided for your convenience.
Mint House Greenville - Downtown
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue, Greenville, SC
Fully refundableReserve now, pay when you stay
$198 nightly
The price is $218 total per night from Oct 5 to Oct 6
$218 total
Oct 5 - Oct 6
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. ...
Hotel Hartness
The Station by Compo Hotels

The Station by Compo Hotels

4 out of 5
745 Old Buncombe Rd, Travelers Rest, SC
$247 nightly
The price is $272 total per night from Sep 21 to Sep 22
$272 total
Sep 21 - Sep 22
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Barbecue grills are provided for your convenience.
The Station by Compo Hotels
Park Place Apartments by Landing

Park Place Apartments by Landing

4 out of 5
300 Hammett St, Greenville, SC
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A gym and a virtual front desk are also provided.
Park Place Apartments by Landing
Hotel Domestique

Hotel Domestique

4 out of 5
10 Road of Vines, Travelers Rest, SC
$459 nightly
The price is $505 total per night from Sep 8 to Sep 9
$505 total
Sep 8 - Sep 9
Total with taxes and fees
This hotel features a restaurant, an outdoor tennis court, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like cooked-to-order breakfast and ...
Hotel Domestique
Southern Sunshine Retreat

Southern Sunshine Retreat

4 out of 5
901 Huntington Rd, Easley, Sc 29642, Usa, Easley, SC
This vacation home includes free WiFi in public areas and barbecue grills.
Southern Sunshine Retreat
Doubletree By Hilton Greenville Airport

Doubletree By Hilton Greenville Airport

4 out of 5
125 The Parkway, Greer, SC
A 24-hour gym is available at this hotel. Take advantage of the free self parking.
Doubletree By Hilton Greenville Airport
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4 Star Hotels Greenville - Spartanburg

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Greenville - Spartanburg 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Greenville - Spartanburg will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Greenville - Spartanburg, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.