Explore top 2025 4 Star Hotels in Greenville - Spartanburg

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Top Greenville - Spartanburg 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY, Greenville, SC
Fully refundableReserve now, pay when you stay
$297 nightly
The price is $327 total per night from Oct 26 to Oct 27
$327 total
Oct 26 - Oct 27
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
9.4/10 Exceptional! (394 reviews)
"Excellent welcome at check in. Very clean room and all hotel areas."

Reviewed on Oct 17, 2025

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
$209 nightly
The price is $230 total per night from Nov 2 to Nov 3
$230 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...
9.2/10 Wonderful! (1,004 reviews)
"Very courteous and helpful staff"

Reviewed on Oct 4, 2025

Opens in a new windowThe Westin Poinsett Greenville
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue, Greenville, SC
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $219 total per night from Nov 17 to Nov 18
$219 total
Nov 17 - Nov 18
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. ...
9.8/10 Exceptional! (603 reviews)
"This was a wonderful hotel. Staff were fantastic! My wife and I came in for a night to eat at Hall’s Chop House and we were recommended to try this hotel and it was fantastic. I’m in sales and I loved the level of paying attention to the details. I mentioned we came in for my bday and they had a ..."

Reviewed on Oct 18, 2025

Opens in a new windowHotel Hartness
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E, Greenville, SC
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $125 total per night from Nov 15 to Nov 16
$125 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-in, ...
8.4/10 Very Good! (597 reviews)
"Staff were friendly and helpful. Breakfast was good. Location was good. The property is reaching a point were it could use a refresh."

Reviewed on Oct 12, 2025

Opens in a new windowGreenville Marriott
Mint House Greenville - Downtown

Mint House Greenville - Downtown

4 out of 5
101 Falls Park Dr, Greenville, SC
$147 nightly
The price is $162 total per night from Oct 27 to Oct 28
$162 total
Oct 27 - Oct 28
Total with taxes and fees
A 24-hour gym is featured at this apartment, along with express check-in and express check-out. Laundry facilities are provided for your convenience.
9.2/10 Wonderful! (749 reviews)
"Excellent stay as always!"

Reviewed on Oct 17, 2025

Opens in a new windowMint House Greenville - Downtown
Park Place Apartments by Landing

Park Place Apartments by Landing

4 out of 5
31 Victor St, Greenville, SC
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A gym and a virtual front desk are also provided.
7.6/10 Good! (40 reviews)
"Great access to bike trail. No working elevator and 3 flights of stairs with luggage is a challenge."

Reviewed on Jun 19, 2025

Opens in a new windowPark Place Apartments by Landing
Hotel Domestique

Hotel Domestique

4 out of 5
10 Road of Vines, Travelers Rest, SC
$439 nightly
The price is $483 total per night from Nov 2 to Nov 3
$483 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, an outdoor tennis court, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like cooked-to-order breakfast and ...
9.6/10 Exceptional! (30 reviews)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."

Reviewed on Jul 27, 2025

Opens in a new windowHotel Domestique
The Station by Compo Hotels

The Station by Compo Hotels

4 out of 5
745 Old Buncombe Rd, Travelers Rest, SC
$270 nightly
The price is $298 total per night from Nov 19 to Nov 20
$298 total
Nov 19 - Nov 20
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Barbecue grills are provided for your convenience.
10/10 Exceptional! (12 reviews)
"This is my third time staying at the station and it didn’t disappoint! I love the comfy beds and the green space around the rooms. What a beautiful area!"

Reviewed on Jul 26, 2025

Opens in a new windowThe Station by Compo Hotels
Southern Sunshine Retreat

Southern Sunshine Retreat

4 out of 5
901 Huntington Rd, Easley, Sc 29642, Usa, Easley, SC
This vacation home includes free WiFi in public areas and barbecue grills.
Opens in a new windowSouthern Sunshine Retreat
Doubletree By Hilton Greenville Airport

Doubletree By Hilton Greenville Airport

4 out of 5
125 The Parkway, Greer, SC
A 24-hour gym is available at this hotel. Take advantage of the free self parking.
Opens in a new windowDoubletree By Hilton Greenville Airport
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4 Star Hotels Greenville - Spartanburg

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Greenville - Spartanburg 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Greenville - Spartanburg will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Greenville - Spartanburg, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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