Explore top 2026 4 Star Hotels in Greenville - Spartanburg

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May 29 - May 31
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Top Greenville - Spartanburg 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$361 nightly
The price is $396 total per night from Jun 14 to Jun 15
$396 total
Jun 14 - Jun 15
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.6/10 Exceptional! (494 reviews)
"Beautiful stay!"

Reviewed on May 23, 2026

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
$219 nightly
The price is $241 total per night from Jun 1 to Jun 2
$241 total
Jun 1 - Jun 2
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. ...
9.8/10 Exceptional! (723 reviews)
"We loved the property! Lush, green hiking trails with ponds and a farm, right behind the hotel. The hotel staff were all very friendly and helpful. The hotel was meticulously maintained. One evening, I witnessed a hotel employee doing an inspection of the pool and even ran his hand over every Adirondack ..."

Reviewed on May 18, 2026

Opens in a new windowHotel Hartness
Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa

4 out of 5
101 Falls Park Dr Greenville SC
$109 nightly
The price is $120 total per night from Jun 22 to Jun 23
$120 total
Jun 22 - Jun 23
Total with taxes and fees
A 24-hour gym, self parking, and laundry facilities are featured at this apartment. Express check-in and express check-out are also provided.
9.2/10 Wonderful! (831 reviews)
"Overall this was a good experience. The location was amazing. The bed was awesome. My only complaint was that the floors had not been properly cleaned in quite some time and there was a slight musty odor upon arrival. I used some essential oils to take care of that…but I never walked barefoot in ..."

Reviewed on May 24, 2026

Opens in a new windowMint House Greenville Downtown by Kasa
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E Greenville SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $130 total per night from Jun 5 to Jun 6
$130 total
Jun 5 - Jun 6
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-in, ...
8.6/10 Excellent! (654 reviews)
"The staff during check-in were friendly and efficient. They even were able to add my stay to my Bonvoy, since I couldn’t due to my business trip being reserved via a 3rd party."

Reviewed on May 24, 2026

Opens in a new windowGreenville Marriott
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St Greenville SC
$222 nightly
The price is $244 total per night from May 28 to May 29
$244 total
May 28 - May 29
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...
9.2/10 Wonderful! (1,004 reviews)
"Wonderful room, view, amenities and customer service"

Reviewed on May 23, 2026

Opens in a new windowThe Westin Poinsett Greenville
Doubletree By Hilton Greenville Airport

Doubletree By Hilton Greenville Airport

4 out of 5
125 The Parkway Greer SC
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $153 total per night from Jun 15 to Jun 16
$153 total
Jun 15 - Jun 16
Total with taxes and fees
A 24-hour gym is available at this hotel. Take advantage of the free self parking.
10/10 Exceptional! (4 reviews)
"Great new hotel. We will stay again."

Reviewed on May 11, 2026

Opens in a new windowDoubletree By Hilton Greenville Airport
The Station by Compo Hotels

The Station by Compo Hotels

4 out of 5
745 Old Buncombe Rd Travelers Rest SC
$333 nightly
The price is $366 total per night from Jun 24 to Jun 25
$366 total
Jun 24 - Jun 25
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Barbecue grills are provided for your convenience.
10/10 Exceptional! (19 reviews)
"Swamp rabbit trail and restaurants very close"

Reviewed on Apr 2, 2026

Opens in a new windowThe Station by Compo Hotels
Hotel Domestique

Hotel Domestique

4 out of 5
10 Road of Vines Travelers Rest SC
$409 nightly
The price is $450 total per night from May 28 to May 29
$450 total
May 28 - May 29
Total with taxes and fees
This hotel features a restaurant, an outdoor tennis court, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like cooked-to-order breakfast and ...
Opens in a new windowHotel Domestique
Landing Apartments Greer - Sugar Creek

Landing Apartments Greer - Sugar Creek

4 out of 5
3000 Daventry Cir Greer SC
This apartment features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self ...
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Opens in a new windowLanding Apartments Greer - Sugar Creek
Landing Apartments - Lyman

Landing Apartments - Lyman

4 out of 5
610 Universal Drive Lyman SC
This aparthotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
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Opens in a new windowLanding Apartments - Lyman
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Greenville - Spartanburg

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Greenville - Spartanburg 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Greenville - Spartanburg will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Greenville - Spartanburg, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Greenville - Spartanburg hotel reviews by fellow wanderers

Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

5 out of 5
Posted 3 hours ago
Travelocity Verified Review
"Awesome people and helped so much, let me checl in early so my wife could rest from her cancer treatment"
A verified traveler stayed at Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & Suites

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