American Airlines Flight AA5645 Deals & Information (2025/2026)

Wander Wisely with exceptional service, 24/7 supportOpens in a new window

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

American Airlines Flight 5645 Route Deals From $166

The cheapest prices found with in the last 7 days for return flights were $274 and $166 for one-way flights to Ronald Reagan Washington National for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Aug 28 - Mon, Sep 1
DSM
Des Moines Intl.
DCA
Ronald Reagan Washington National
$274 Roundtrip, found 3 days ago
$274
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Aug 28 from Des Moines Intl. to Ronald Reagan Washington National, returning Mon, Sep 1, priced at $274 found 3 days ago
Thu, Aug 28 - Mon, Sep 1
DSM
Des Moines Intl.
DCA
Ronald Reagan Washington National
$285 Roundtrip, found 3 days ago
$285
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Aug 28 from Des Moines Intl. to Ronald Reagan Washington National, returning Mon, Sep 1, priced at $285 found 3 days ago
Wed, Sep 17 - Fri, Sep 19
DSM
Des Moines Intl.
DCA
Ronald Reagan Washington National
$298 Roundtrip, found 5 days ago
$298
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Sep 17 from Des Moines Intl. to Ronald Reagan Washington National, returning Fri, Sep 19, priced at $298 found 5 days ago
Sat, Oct 11 - Wed, Oct 15
DSM
Des Moines Intl.
DCA
Ronald Reagan Washington National
$306 Roundtrip, found 5 days ago
$306
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Oct 11 from Des Moines Intl. to Ronald Reagan Washington National, returning Wed, Oct 15, priced at $306 found 5 days ago
Thu, Aug 28 - Mon, Sep 1
DSM
Des Moines Intl.
DCA
Ronald Reagan Washington National
$312 Roundtrip, found 3 days ago
$312
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Aug 28 from Des Moines Intl. to Ronald Reagan Washington National, returning Mon, Sep 1, priced at $312 found 3 days ago
Sun, Sep 7 - Tue, Sep 9
DSM
Des Moines Intl.
DCA
Ronald Reagan Washington National
$315 Roundtrip, just found
$315
Roundtrip
just found
Select American Airlines flight, departing Sun, Sep 7 from Des Moines Intl. to Ronald Reagan Washington National, returning Tue, Sep 9, priced at $315 just found
Thu, Dec 25 - Tue, Dec 30
DSM
Des Moines Intl.
DCA
Ronald Reagan Washington National
$323 Roundtrip, found 5 days ago
$323
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Dec 25 from Des Moines Intl. to Ronald Reagan Washington National, returning Tue, Dec 30, priced at $323 found 5 days ago
Sun, Sep 7 - Tue, Sep 9
DSM
Des Moines Intl.
DCA
Ronald Reagan Washington National
$330 Roundtrip, just found
$330
Roundtrip
just found
Select American Airlines flight, departing Sun, Sep 7 from Des Moines Intl. to Ronald Reagan Washington National, returning Tue, Sep 9, priced at $330 just found

Frequently asked questions

What route does flight number AA5645 take?
AA5645 serves multiple routes, but the most common is between Charlotte-Douglas Intl. Airport (CLT) and ILM. If you manage to score a direct flight, you'll arrive in about 1 hour and 6 minutes. Multi-stop flights can also use the same number, as can flights on other routes.
How often is AA5645 on time?
American Airlines flight number AA5645 from Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.) to Wilmington Intl. Airport lands according to schedule 100% of the time, meaning you can rest assured you will reach your destination ASAP. When it is running behind schedule, it is generally delayed by 4 minutes. This flight has a 4.3-star rating.
What kind of plane is on flight number AA5645?
You're likely to be hopping on board a Bombardier CRJ900 if you've booked a ticket on flight AA5645 from Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.) to ILM. It's the most commonly used type of aircraft on this particular route.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA5645 flight with Travelocity, please visit our Customer Service Portal.