American Airlines Flight 4645 Deals & Information (2026/2027)

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American Airlines Flight 4645 Route Deals From $75

The cheapest prices found with in the last 7 days for return flights were $161 and $75 for one-way flights to LaGuardia for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Aug 5 - Thu, Aug 6
DCA
Ronald Reagan Washington National
LGA
LaGuardia
$161 Roundtrip, found 20 hours ago
$161
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Aug 5 from Ronald Reagan Washington National to LaGuardia, returning Thu, Aug 6, priced at $161 found 20 hours ago
Fri, Aug 7 - Sun, Aug 9
DCA
Ronald Reagan Washington National
LGA
LaGuardia
$182 Roundtrip, found 21 hours ago
$182
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Fri, Aug 7 from Ronald Reagan Washington National to LaGuardia, returning Sun, Aug 9, priced at $182 found 21 hours ago
Wed, Jul 22 - Fri, Jul 24
DCA
Ronald Reagan Washington National
LGA
LaGuardia
$191 Roundtrip, found 5 days ago
$191
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Jul 22 from Ronald Reagan Washington National to LaGuardia, returning Fri, Jul 24, priced at $191 found 5 days ago
Mon, Aug 3 - Tue, Aug 4
DCA
Ronald Reagan Washington National
LGA
LaGuardia
$192 Roundtrip, found 3 days ago
$192
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Aug 3 from Ronald Reagan Washington National to LaGuardia, returning Tue, Aug 4, priced at $192 found 3 days ago
Sun, Oct 11 - Thu, Oct 22
DCA
Ronald Reagan Washington National
LGA
LaGuardia
$199 Roundtrip, found 2 hours ago
$199
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sun, Oct 11 from Ronald Reagan Washington National to LaGuardia, returning Thu, Oct 22, priced at $199 found 2 hours ago
Wed, Aug 5 - Tue, Aug 11
DCA
Ronald Reagan Washington National
LGA
LaGuardia
$214 Roundtrip, found 1 day ago
$214
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Aug 5 from Ronald Reagan Washington National to LaGuardia, returning Tue, Aug 11, priced at $214 found 1 day ago
Fri, Aug 7 - Sun, Aug 9
DCA
Ronald Reagan Washington National
LGA
LaGuardia
$217 Roundtrip, found 21 hours ago
$217
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Fri, Aug 7 from Ronald Reagan Washington National to LaGuardia, returning Sun, Aug 9, priced at $217 found 21 hours ago
Sun, Oct 11 - Thu, Oct 22
DCA
Ronald Reagan Washington National
LGA
LaGuardia
$228 Roundtrip, found 2 hours ago
$228
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sun, Oct 11 from Ronald Reagan Washington National to LaGuardia, returning Thu, Oct 22, priced at $228 found 2 hours ago
Fri, Jul 31 - Sun, Aug 2
DCA
Ronald Reagan Washington National
LGA
LaGuardia
$230 Roundtrip, just found
$230
Roundtrip
just found
Select American Airlines flight, departing Fri, Jul 31 from Ronald Reagan Washington National to LaGuardia, returning Sun, Aug 2, priced at $230 just found
Fri, Jul 24 - Sun, Jul 26
DCA
Ronald Reagan Washington National
LGA
LaGuardia
$232 Roundtrip, found 1 hour ago
$232
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Fri, Jul 24 from Ronald Reagan Washington National to LaGuardia, returning Sun, Jul 26, priced at $232 found 1 hour ago

Frequently asked questions

What route does flight number AA4645 take?
You'll be landing at Key West Intl. Airport from New York, NY Airport (LGA-LaGuardia) if you've booked a ticket on flight number AA4645. You'll be airborne for 3 hours and 20 minutes during this trip. It's also good to note that it conveniently travels non-stop.
What terminal does AA4645 fly out of?
Flight number AA4645 runs between LGA and EYW, and those booked on this flight normally board the aircraft from Terminal B.
What kind of plane is on flight number AA4645?
The route for AA4645 is usually LGA to Key West Intl. Airport, and the Embraer 175 is the type of plane you'll probably be taking off on.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4645 flight with Travelocity, please visit our Customer Service Portal.