American Airlines Flight 4604 Deals & Information (2026/2027)

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American Airlines Flight 4604 Route Deals From $165

The cheapest prices found with in the last 7 days for return flights were $271 and $165 for one-way flights to LaGuardia for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Oct 31 - Sat, Nov 7
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$271 Roundtrip, found 4 days ago
$271
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 31 from John Glenn Columbus Intl. to LaGuardia, returning Sat, Nov 7, priced at $271 found 4 days ago
Wed, Nov 25 - Wed, Dec 2
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$281 Roundtrip, found 8 hours ago
$281
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Nov 25 from John Glenn Columbus Intl. to LaGuardia, returning Wed, Dec 2, priced at $281 found 8 hours ago
Wed, Nov 25 - Wed, Dec 2
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$291 Roundtrip, found 8 hours ago
$291
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Nov 25 from John Glenn Columbus Intl. to LaGuardia, returning Wed, Dec 2, priced at $291 found 8 hours ago
Wed, Nov 25 - Wed, Dec 2
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$305 Roundtrip, found 8 hours ago
$305
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Nov 25 from John Glenn Columbus Intl. to LaGuardia, returning Wed, Dec 2, priced at $305 found 8 hours ago

Frequently asked questions

What route does flight number AA4604 take?
AA4604 flies straight between Portland Intl. Jetport Airport (PWM) and O'Hare Airport in about 2 hours and 52 minutes. It can sometimes take other routes though, some of which may be multi-stop trips. Keep this in mind when booking your seat to avoid any confusion.
What kind of plane is on flight number AA4604?
If you're on flight AA4604 from Portland, ME Airport (PWM-Portland Intl. Jetport) to O'Hare Intl. Airport (ORD), you'll likely be jetting off on an Embraer 175. Flight AA4604 serves several routes, but this is the most popular one.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4604 flight with Travelocity, please visit our Customer Service Portal.