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American Airlines Flights from Roanoke (ROA) to Des Moines (DSM) from $167

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Amazing American Airlines ROA to DSM Flight Deals

The cheapest flights to Des Moines Intl. found within the past 7 days were $290 round trip and $167 one way. Prices and availability subject to change. Additional terms may apply.

Fri, May 14 -
ROA
Roanoke
to
DSM
Des Moines
$167

One way

found 2 days ago

Open ROA to DSM flights search result page
Fri, May 14 -
ROA
Roanoke
to
DSM
Des Moines
$217

One way

found 2 days ago

Open ROA to DSM flights search result page
Sun, Jul 25 -
ROA
Roanoke
to
DSM
Des Moines
$287

One way

found 6 days ago

Open ROA to DSM flights search result page
Fri, Apr 30 - Sun, May 2
ROA
Roanoke
to
DSM
Des Moines
$290

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, Apr 2 - Sun, Apr 4
ROA
Roanoke
to
DSM
Des Moines
$303

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, Apr 2 - Sun, Apr 4
ROA
Roanoke
to
DSM
Des Moines
$316

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, Apr 2 - Sun, Apr 4
ROA
Roanoke
to
DSM
Des Moines
$332

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, Apr 9 - Sun, Apr 11
ROA
Roanoke
to
DSM
Des Moines
$337

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, May 14 - Sun, May 16
ROA
Roanoke
to
DSM
Des Moines
$338

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, May 14 - Sun, May 16
ROA
Roanoke
to
DSM
Des Moines
$344

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, Apr 2 - Sun, Apr 4
ROA
Roanoke
to
DSM
Des Moines
$345

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, Apr 30 - Sun, May 2
ROA
Roanoke
to
DSM
Des Moines
$348

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, Apr 30 - Sun, May 2
ROA
Roanoke
to
DSM
Des Moines
$290

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, Apr 2 - Sun, Apr 4
ROA
Roanoke
to
DSM
Des Moines
$303

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, Apr 2 - Sun, Apr 4
ROA
Roanoke
to
DSM
Des Moines
$316

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, Apr 2 - Sun, Apr 4
ROA
Roanoke
to
DSM
Des Moines
$332

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, Apr 9 - Sun, Apr 11
ROA
Roanoke
to
DSM
Des Moines
$337

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, Apr 2 - Sun, Apr 4
ROA
Roanoke
to
DSM
Des Moines
$345

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, Apr 30 - Sun, May 2
ROA
Roanoke
to
DSM
Des Moines
$348

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, May 14 -
ROA
Roanoke
to
DSM
Des Moines
$167

One way

found 2 days ago

Open ROA to DSM flights search result page
Fri, May 14 -
ROA
Roanoke
to
DSM
Des Moines
$217

One way

found 2 days ago

Open ROA to DSM flights search result page
Fri, May 14 - Sun, May 16
ROA
Roanoke
to
DSM
Des Moines
$338

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Fri, May 14 - Sun, May 16
ROA
Roanoke
to
DSM
Des Moines
$344

Roundtrip

found 2 days ago

Open ROA to DSM flights search result page
Sun, Jul 25 -
ROA
Roanoke
to
DSM
Des Moines
$287

One way

found 6 days ago

Open ROA to DSM flights search result page

Travelers ❤️ these 🏨 after their flight to Des Moines

Price for 1 night 2 adults*

Days Inn & Suites by Wyndham Des Moines Airport
Days Inn & Suites by Wyndham Des Moines Airport
2.0 out of 5.0 1901 Hackley Ave, Des Moines, IA
$53

Per night/room

Mar 14 - Mar 15

4.2/5 (44 reviews)

Everything was good. No complaints. Front desk was vey nice and helpful.

Reviewed on Oct 5, 2020
This hotel features an indoor pool and a fitness center. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
Hampton Inn Des Moines Airport
Hampton Inn Des Moines Airport
2.5 out of 5.0 5001 Fleur Dr, Des Moines, IA
$84

Per night/room

Mar 6 - Mar 7

4.2/5 (14 reviews)

There were people yelling and making a lot of noise well up to 2:00 am down the hall from us.

Reviewed on Nov 10, 2019
This hotel features a fitness center and a seasonal outdoor pool. There's no skimping on freebies - guests receive free WiFi, free self parking, and a free airport ...
Holiday Inn Des Moines-Airport/Conf Center
Holiday Inn Des Moines-Airport/Conf Center
3.0 out of 5.0 6111 Fleur Dr, Des Moines, IA
$87

Per night/room

Mar 8 - Mar 9

3.8/5 (19 reviews)

Room was clean but smelled like smoke! Bed was comfortable and the shower was great! The airport shuttle driver was friendly and knowledgeable!

Reviewed on Jul 3, 2020
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour fitness center and perks like free self parking and a free airport shuttle. ...

Popular American Airlines Flight Routes from ROA

Top American Airlines Flight Routes from DSM

Top Flights for American Airlines originating from ROA

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.