
$110 Cheap American Airlines flights from Pensacola to Buffalo (PNS to BUF)
Find The Best Day To Fly from Pensacola to Buffalo
Amazing American Airlines PNS to BUF Flight Deals
The cheapest flights to Buffalo Niagara Intl. found within the past 7 days were $217 round trip and $110 one way. Prices and availability subject to change. Additional terms may apply.
PNS
Pensacola
BUF
Buffalo
$217 Roundtrip, found 1 day ago
$217
Roundtrip
found 1 day ago
PNS
Pensacola
BUF
Buffalo
$220 Roundtrip, found 1 day ago
$220
Roundtrip
found 1 day ago
PNS
Pensacola
BUF
Buffalo
$245 Roundtrip, found 1 day ago
$245
Roundtrip
found 1 day ago
PNS
Pensacola
BUF
Buffalo
$246 Roundtrip, found 1 day ago
$246
Roundtrip
found 1 day ago
PNS
Pensacola
BUF
Buffalo
$267 Roundtrip, found 12 hours ago
$267
Roundtrip
found 12 hours ago
PNS
Pensacola
BUF
Buffalo
$281 Roundtrip, found 1 day ago
$281
Roundtrip
found 1 day ago
Frequently asked questions
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to Buffalo

Sleep Inn & Suites Buffalo Airport
100 Holtz Dr, Buffalo, NY
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
7.8/10 Good! (1,597 reviews)
"Comfortable room. Clean and updated. Good breakfast. Has a shuttle for airport."
Reviewed on Jun 15, 2025

Buffalo Airport Hotel
4600 Genesee St, Buffalo, NY
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8/10 Very Good! (2,495 reviews)
"Still needs a little work but looks good. Every one was very friendly"
Reviewed on Jun 13, 2025

Fairfield Inn & Suites by Marriott Buffalo Airport
4271 Genesee Street, Buffalo, NY
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free ...
8.6/10 Excellent! (1,002 reviews)
"The people were nice, and the hotel was spotless. An enjoyable stay."
Reviewed on Jun 15, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular American Airlines Flight Routes from PNS
Top American Airlines Flight Routes from BUF
- American Airlines BUF to JFK
- American Airlines BUF to DFW
- American Airlines BUF to MLB
- American Airlines BUF to HNL
- American Airlines BUF to ATL
- American Airlines BUF to ECP
- American Airlines BUF to RSW
- American Airlines BUF to MBJ
- American Airlines BUF to CLT
- American Airlines BUF to MCO
- American Airlines BUF to MIA
Top Flights for American Airlines originating from PNS
Domestic
- Los Angeles to San Salvador (LAX - SAL)
- San Juan to Orlando (SJU - MCO)
- Orlando to San Juan (MCO - SJU)
- Philadelphia to Orlando (PHL - MCO)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Philadelphia to San Juan (PHL - SJU)
- New York to Santiago (JFK - STI)
- New York to Orlando (JFK - MCO)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- New York to San Juan (JFK - SJU)
International
- New York to Orlando (LGA - MCO)
- Chicago to San Juan (ORD - SJU)
- Los Angeles to Honolulu (LAX - HNL)
- Los Angeles to Guatemala City (LAX - GUA)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Orlando to San Juan (MCO - SJU)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- Philadelphia to Orlando (PHL - MCO)
- New York to San Juan (JFK - SJU)
Most Popular
Flights
Atlanta to Miami (ATL - MIA)Philadelphia to Miami (PHL - MIA)JetBlue Airways Boston (BOS) to Orlando (MCO) flightsJetBlue Airways Orlando (MCO) to Las Vegas (LAS) flightsBoston to Miami (BOS - MIA)New York to Fort Lauderdale (JFK - FLL)Raleigh to Orlando (RDU - MCO)Baltimore to Orlando (BWI - MCO)Chicago to Orlando (ORD - MCO)Los Angeles to Orlando (LAX - MCO)Los Angeles to Miami (LAX - MIA)Minneapolis to Orlando (MSP - MCO)Dallas to Orlando (DFW - MCO)Los Angeles to New York (LAX - JFK)Orlando to San Juan (MCO - SJU)New York to Los Angeles (JFK - LAX)New York to Orlando (JFK - MCO)New York to Miami (JFK - MIA)Hawaiian Airlines Orlando (MCO) to Honolulu (HNL) flightsPhiladelphia to Tampa (PHL - TPA)San Francisco to New York (SFO - JFK)New York to Atlanta (JFK - ATL)Philadelphia to Orlando (PHL - MCO)Newark Liberty Intl. Airport to Orlando (EWR - MCO)Detroit to Orlando (DTW - MCO)New York to London (JFK - LHR)Dallas to Miami (DFW - MIA)Hartford to Orlando (BDL - MCO)New York to San Francisco (JFK - SFO)Atlanta to Orlando (ATL - MCO)