
$179 Cheap American Airlines flights from Cleveland to Knoxville (CLE to TYS)
Find The Best Day To Fly from Cleveland to Knoxville
Amazing American Airlines CLE to TYS Flight Deals
The cheapest flights to McGhee Tyson found within the past 7 days were $233 round trip and $179 one way. Prices and availability subject to change. Additional terms may apply.
TYS From CLE Economy Coach Packages on Similar Airlines



Frequently asked questions
Discover our best American Airlines flight from Cleveland CLE to Knoxville TYS
To find the best deals on flights to Cleveland from Knoxville with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Cleveland CLE to Knoxville TYS with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $233 to $273, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Cleveland CLE to Knoxville TYS
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Cleveland to Knoxville costs from $179. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Knoxville TYS from Cleveland CLE with American Airlines
To find a cheap American Airlines flight from Cleveland CLE to Knoxville TYS, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Cleveland CLE to Knoxville TYS
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as August, or if you book a flight with a stopover.
Find nonstop flights from Cleveland CLE to Knoxville TYS with American Airlines
If you’re keen to be on Knoxville soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Cleveland CLE to Knoxville TYS
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Knoxville TYS from Cleveland CLE with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
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Popular American Airlines Flight Routes from CLE
- American Airlines CLE to ORD
- American Airlines CLE to IAH
- American Airlines CLE to BNA
- American Airlines CLE to LAX
- American Airlines CLE to DUB
- American Airlines CLE to FLL
- American Airlines CLE to MIA
- American Airlines CLE to TPA
- American Airlines CLE to MCO
- American Airlines CLE to LGA
- American Airlines CLE to LAS
- American Airlines CLE to SEA
Top Flights for American Airlines originating from CLE
Domestic
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Philadelphia to San Juan (PHL - SJU)
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
- Philadelphia to Orlando (PHL - MCO)
- Atlanta to New York (ATL - LGA)
- Atlanta to New York (ATL - LGA)
- Los Angeles to San Salvador (LAX - SAL)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- New York to San Juan (JFK - SJU)
- Philadelphia to Orlando (PHL - MCO)
International
- Orlando to San Juan (MCO - SJU)
- New York to Orlando (LGA - MCO)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- New York to Montego Bay (JFK - MBJ)
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- New York to Santo Domingo (JFK - SDQ)
- Atlanta to New York (ATL - LGA)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Philadelphia to San Juan (PHL - SJU)