Cheap American Airlines flights from Champaign to Knoxville (CMI to TYS)

Find The Best Day To Fly from Champaign to Knoxville

Amazing American Airlines CMI to TYS Flight Deals

The cheapest flights to McGhee Tyson found within the past 7 days were $318 round trip and one way. Prices and availability subject to change. Additional terms may apply.

Mon, Sep 15 - Tue, Oct 7
CMI
Champaign
TYS
Knoxville
$318 Roundtrip, found 2 days ago
$318
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Sep 15 from Champaign to Knoxville, returning Tue, Oct 7, priced at $318 found 2 days ago
Wed, Aug 6 - Sat, Aug 9
CMI
Champaign
TYS
Knoxville
$378 Roundtrip, found 2 days ago
$378
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Aug 6 from Champaign to Knoxville, returning Sat, Aug 9, priced at $378 found 2 days ago
Mon, Sep 15 - Tue, Oct 7
CMI
Champaign
TYS
Knoxville
$384 Roundtrip, found 2 days ago
$384
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Sep 15 from Champaign to Knoxville, returning Tue, Oct 7, priced at $384 found 2 days ago
Tue, Aug 5 - Sat, Aug 9
CMI
Champaign
TYS
Knoxville
$384 Roundtrip, found 2 days ago
$384
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Aug 5 from Champaign to Knoxville, returning Sat, Aug 9, priced at $384 found 2 days ago
Sun, Aug 3 - Sat, Aug 9
CMI
Champaign
TYS
Knoxville
$390 Roundtrip, found 2 days ago
$390
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Aug 3 from Champaign to Knoxville, returning Sat, Aug 9, priced at $390 found 2 days ago
Fri, Aug 1 - Wed, Aug 6
CMI
Champaign
TYS
Knoxville
$395 Roundtrip, found 2 days ago
$395
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Aug 1 from Champaign to Knoxville, returning Wed, Aug 6, priced at $395 found 2 days ago
Wed, Sep 17 - Sat, Oct 4
CMI
Champaign
TYS
Knoxville
$438 Roundtrip, found 2 days ago
$438
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Sep 17 from Champaign to Knoxville, returning Sat, Oct 4, priced at $438 found 2 days ago
Mon, Sep 15 - Sat, Oct 4
CMI
Champaign
TYS
Knoxville
$444 Roundtrip, found 2 days ago
$444
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Sep 15 from Champaign to Knoxville, returning Sat, Oct 4, priced at $444 found 2 days ago
Sat, Sep 13 - Sat, Oct 4
CMI
Champaign
TYS
Knoxville
$445 Roundtrip, found 2 days ago
$445
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Sep 13 from Champaign to Knoxville, returning Sat, Oct 4, priced at $445 found 2 days ago
Wed, Sep 17 - Mon, Oct 6
CMI
Champaign
TYS
Knoxville
$468 Roundtrip, found 2 days ago
$468
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Sep 17 from Champaign to Knoxville, returning Mon, Oct 6, priced at $468 found 2 days ago
Mon, Sep 15 - Mon, Oct 6
CMI
Champaign
TYS
Knoxville
$474 Roundtrip, found 2 days ago
$474
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Sep 15 from Champaign to Knoxville, returning Mon, Oct 6, priced at $474 found 2 days ago
Sat, Sep 13 - Mon, Oct 6
CMI
Champaign
TYS
Knoxville
$476 Roundtrip, found 2 days ago
$476
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Sep 13 from Champaign to Knoxville, returning Mon, Oct 6, priced at $476 found 2 days ago
American Airlines Airports
Hop on a(n) American Airlines flight today by flying to many destinations out of these domestic and international airports:
Airport code
Country
Airport name
Number of flights
DFWUSADallas-Fort Worth Intl.599
CLTUSACharlotte-Douglas Intl.536
ORDUSAO'Hare Intl.317
PHLUSAPhiladelphia Intl.247
MIAUSAMiami Intl.193
DCAUSARonald Reagan Washington National152
PHXUSASky Harbor Intl.141
LAXUSALos Angeles Intl.81
LGAUSALaGuardia72
BOSUSALogan Intl.57

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3.5 out of 5
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Hilton Knoxville Airport
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La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
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La Quinta Inn & Suites by Wyndham Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
8.4/10 Very Good! (1,014 reviews)
"Very clean"

Reviewed on Jul 16, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.