Cheap Flights to Upstate South Carolina from $53
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How Much Does it Cost To Fly To Upstate South Carolina?
The cheapest prices found with in the last 7 days for return flights were $102 and $53 for one-way flights to Upstate South Carolina for the period specified. Prices and availability are subject to change. Additional terms apply
MCO
Orlando Intl.
GSP
Greenville-Spartanburg Intl.
$102 Roundtrip, found 2 days ago
$102
Roundtrip
found 2 days ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| DCA | Greer | June 3 to June 8 | $178 |
| IAH | Fletcher | June 3 to June 6 | $253 |
| LGA | Greer | July 3 to July 8 | $259 |
| EWR | Greer | May 24 to May 31 | $259 |
| ORD | Greer | June 13 to June 20 | $261 |
| RFD | Fletcher | May 26 to June 1 | $267 |
| IAH | Greer | May 23 to May 30 | $275 |
| EWR | Fletcher | May 23 to May 27 | $275 |
| EWR | Fletcher | May 23 to May 27 | $275 |
| LGA | Fletcher | July 18 to July 25 | $303 |
| BOS | Fletcher | June 7 to June 13 | $327 |
| DCA | Fletcher | July 8 to July 11 | $353 |
| TTN | Fletcher | May 30 to June 2 | $382 |
| DAL | Greer | June 2 to June 4 | $382 |
| FCO | Greer | May 14 to May 25 | $878 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| EWR | Greer | May 9 to May 12 | $347 |
| EWR | Greer | May 9 to May 12 | $347 |
| DCA | Greer | May 9 to May 16 | $347 |
| IAH | Greer | May 9 to May 13 | $364 |
| ORD | Fletcher | May 8 to May 9 | $371 |
| IAH | Fletcher | May 10 to May 16 | $378 |
| ORD | Greer | May 8 to May 10 | $387 |
| LGA | Fletcher | May 9 to May 12 | $387 |
| LGA | Fletcher | May 9 to May 12 | $387 |
| PHL | Greer | May 8 to May 9 | $486 |
| DFW | Greer | May 10 to May 13 | $501 |
| DCA | Fletcher | May 8 to May 10 | $521 |
| EWR | Fletcher | May 8 to May 9 | $530 |
| DFW | Fletcher | May 8 to May 10 | $634 |
| BOS | Greer | May 9 to May 16 | $635 |
Upstate South Carolina Flight Information
Traveling to | Upstate South Carolina |
|---|---|
Lowest Price | $102 |
Number of Airlines Serving | |
Airlines Serving | Breeze Airways |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Upstate South Carolina Accommodation Deals
Baymont by Wyndham Anderson Clemson
128 Interstate Blvd Anderson SC
$72 nightly
The price is $80 total per night from May 13 to May 14
$80 total
May 13 - May 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (874 reviews)
This motel is grossly overrated. Random pieces of furniture are sitting outside of rooms on walkways. I think my room was supposedly newly renovated, but the result was substandard: toilet paper holder hanging out of the wall and never properly installed, shower bar not installed (just two holes ...
Reviewed on Apr 11, 2026
Days Inn by Wyndham Greenville
60 Roper Mountain Rd Greenville SC
$64 nightly
The price is $70 total per night from May 4 to May 5
$70 total
May 4 - May 5
Total with taxes and fees
Book a stay at this business-friendly motel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (1,001 reviews)
Yes
Reviewed on Apr 14, 2026
Baymont by Wyndham Greenville Woodruff Rd
31 Old Country Rd Greenville SC
$65 nightly
The price is $72 total per night from Jun 1 to Jun 2
$72 total
Jun 1 - Jun 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (1,001 reviews)
Cheap but not a bad hotel it was clean and out the way
Reviewed on May 1, 2026
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Red Roof Inn Spartanburg – I-26
6765 Pottery Rd Spartanburg SC
$61 nightly
The price is $68 total per night from May 16 to May 17
$68 total
May 16 - May 17
Total with taxes and fees
Stay at this hotel in Spartanburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions G.B. Hodge Center and North Town Center are located ...
7/10 Good! (760 reviews)
All good.
Reviewed on Apr 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our Top Upstate South Carolina with Airport Shuttles
Best Western Greenville Airport Inn
5009 Pelham Road Greenville SC
$77 nightly
The price is $84 total per night from May 4 to May 5
$84 total
May 4 - May 5
Total with taxes and fees
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,000 reviews)
Staff made accommodations with no complaints.
Reviewed on Apr 25, 2026
Courtyard Greenville-Spartanburg by Marriott
115 The Pkwy Greer SC
$121 nightly
The price is $133 total per night from May 10 to May 11
$133 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (661 reviews)
The front desk staff Shantis & Brianna were so friendly & helpful at check-in. Richard, our shuttle driver, was prompt & very pleasant, as well as a safe driver. I didn’t get the name of the checkout person this morning, but she was very pleasant & helpful for so early in the morning.
Reviewed on Apr 23, 2026
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
$99 nightly
The price is $109 total per night from May 31 to Jun 1
$109 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room ...
8.6/10 Excellent! (1,001 reviews)
The staff was great at check-in very helpful and quick. The Ruth Chris steakhouse attached to the hotel is a nice touch as well, they did an awesome breakfast buffet and to order breakfast.
Reviewed on Apr 30, 2026
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Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
$110 nightly
The price is $121 total per night from May 25 to May 26
$121 total
May 25 - May 26
Total with taxes and fees
Book a stay at this golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,174 reviews)
We are being a charged for a stay that never happened, even with proof of cancellation!
Reviewed on Apr 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Upstate South Carolina
The Westin Poinsett Greenville
120 South Main St Greenville SC
$202 nightly
The price is $222 total per night from May 17 to May 18
$222 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the ...
9.2/10 Wonderful! (1,002 reviews)
Exceptional experience
Reviewed on May 1, 2026
Hyatt Regency Greenville
220 N Main St Greenville SC
$149 nightly
The price is $163 total per night from May 17 to May 18
$163 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, an outdoor pool, and 2 restaurants. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,002 reviews)
Took forever at the front desk and we were the only people up there. Also, the beds were so horribly noisy. If you rolled over in one of the queen beds in the middle of the night, it was so loud it woke up the person in the other bed.
Reviewed on Apr 29, 2026
Sleep Inn at Greenville Convention Cente
231 N Pleasantburg Dr Greenville SC
$69 nightly
The price is $75 total per night from May 31 to Jun 1
$75 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (1,000 reviews)
far price for the area.
Reviewed on Apr 29, 2026
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The Bleckley Inn
151 E Church St Anderson SC
$180 nightly
The price is $200 total per night from May 12 to May 13
$200 total
May 12 - May 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Anderson. Enjoy free parking, a rooftop terrace, and a fitness center. Popular attractions Church Street Heritage ...
9.8/10 Exceptional! (411 reviews)
Beautiful hotel with outstanding service. I frequent 4 and 5 star hotels, and Bleckley Inn is right with them. The breakfast was excellent, and the location next to the parking garage can’t be beat. EV chargers are available and the first two hours are free. The housekeepers are super attentive and ...
Reviewed on Apr 17, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Upstate South Carolina
Embassy Suites by Hilton Greenville Downtown Riverplace
250 Riverplace Greenville SC
$163 nightly
The price is $180 total per night from May 10 to May 11
$180 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the bar and the helpful staff ...
9.2/10 Wonderful! (1,001 reviews)
The breakfast is always amazing!
Reviewed on Apr 27, 2026
Best Western Greenville Airport Inn
5009 Pelham Road Greenville SC
$77 nightly
The price is $84 total per night from May 4 to May 5
$84 total
May 4 - May 5
Total with taxes and fees
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,000 reviews)
Staff made accommodations with no complaints.
Reviewed on Apr 25, 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
$110 nightly
The price is $121 total per night from May 25 to May 26
$121 total
May 25 - May 26
Total with taxes and fees
Book a stay at this golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,174 reviews)
We are being a charged for a stay that never happened, even with proof of cancellation!
Reviewed on Apr 30, 2026
Save an average of 15% on thousands of hotels when you're signed in
Country Inn & Suites by Radisson, Anderson, SC
116 Interstate Blvd Anderson SC
$101 nightly
The price is $112 total per night from May 31 to Jun 1
$112 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,001 reviews)
Breakfast was great. Room 208 smelled of urine. Tile floors needed some mopping as well as the sticky elevator floor. Staff needs to be proactive rather than relying on guests to report issues. Clock in lobby was an hour off. I liked the room except for the pungent odor of urine especially in the ...
Reviewed on Apr 25, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Upstate South Carolina Flight and Hotel Packages
Upstate South Carolina flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Don't see what you're looking for?
See all available trips from Newark Liberty Intl. Airport to Upstate South Carolina
View all tripsNeed a Car For After Your Flight?
Economy
Greenville, South Carolina, USA
$40
$184 total
found 1 day ago
Compact
Greenville, South Carolina, USA
$41
$188 total
found 1 day ago
Midsize
Greenville, South Carolina, USA
$42
$191 total
found 1 day ago
Standard
Greenville, South Carolina, USA
$43
$195 total
found 1 day ago
Frequently asked questions
Plane Tickets To Upstate South Carolina
Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Upstate South Carolina. Browse through our inventory to explore a wide range of cheap flights to Upstate South Carolina to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Upstate South Carolina as you anxiously await to exit the plane and explore what Upstate South Carolina has to offer. Considering all the amazing local food and culture in Upstate South Carolina, we won't hold this against you.
When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Upstate South Carolina to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Upstate South Carolina without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Upstate South Carolina with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Upstate South Carolina today!
More Ways To Wander
Upstate South Carolina Hotels
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Upstate South Carolina Vacation Rentals
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Upstate South Carolina Car Rentals
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Upstate South Carolina Vacations
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Things to do in Upstate South Carolina
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