Cheap Flights to Upstate South Carolina from $46

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How Much Does it Cost To Fly To Upstate South Carolina?

The cheapest prices found with in the last 7 days for return flights were $92 and $46 for one-way flights to Upstate South Carolina for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
BOSFletcherSeptember 3 to September 6$179
LGAFletcherJuly 9 to July 22$179
LGAFletcherJuly 9 to July 22$179
DCAGreerAugust 1 to August 3$189
ORDGreerJuly 29 to August 3$202
EWRGreerJuly 31 to August 2$209
LGAGreerJuly 24 to July 27$209
IAHFletcherJuly 16 to July 19$211
EWRFletcherJune 25 to June 29$229
IAHGreerAugust 5 to August 12$279
DCAFletcherSeptember 5 to September 13$291
PHLGreerAugust 26 to August 31$296
BOSGreerAugust 31 to September 3$300
DFWFletcherJuly 2 to July 7$365
FCOGreerAugust 6 to September 13$829
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
BOSFletcherJune 8 to June 13$197
LGAFletcherJune 7 to June 20$248
LGAFletcherJune 7 to June 20$248
ORDGreerJune 6 to June 11$270
LGAGreerJune 7 to June 10$273
ORDFletcherJune 7 to June 11$275
DCAGreerJune 7 to June 16$277
EWRFletcherJune 6 to June 23$302
IAHFletcherJune 6 to June 14$386
DCAFletcherJune 7 to June 14$412
PHLFletcherJune 7 to June 11$439
DFWGreerJune 7 to June 11$485
BOSGreerJune 8 to June 11$537
DFWFletcherJune 7 to June 11$557
IAHGreerJune 6 to June 15$569
*Prices include taxes and fees

Upstate South Carolina Flight Information

Traveling to
Upstate South Carolina
Lowest Price
$92
Number of Airlines Serving
Airlines Serving
Breeze Airways
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Upstate South Carolina Accommodation Deals

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

2.5 out of 5
128 Interstate Blvd, Anderson, SC
$72 nightly
The price is $80 total per night from Jun 9 to Jun 10
$80 total
Jun 9 - Jun 10
Total includes taxes and fees
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (789 reviews)
"Nice place for decent price"

Reviewed on May 30, 2025

Baymont by Wyndham Anderson Clemson
Days Inn by Wyndham Greenville

Days Inn by Wyndham Greenville

2 out of 5
60 Roper Mountain Rd, Greenville, SC
$60 nightly
The price is $66 total per night from Jun 8 to Jun 9
$66 total
Jun 8 - Jun 9
Total includes taxes and fees
Book a stay at this business-friendly motel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.8/10 (1,001 reviews)
"It was fine"

Reviewed on May 27, 2025

Days Inn by Wyndham Greenville
Baymont by Wyndham Greenville Woodruff Rd

Baymont by Wyndham Greenville Woodruff Rd

2.5 out of 5
31 Old Country Rd, Greenville, SC
$73 nightly
The price is $80 total per night from Jun 29 to Jun 30
$80 total
Jun 29 - Jun 30
Total includes taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (1,001 reviews)
"It was comfortable and quiet for the most part. Next to everything. Staff was friendly and efficient!"

Reviewed on May 27, 2025

Baymont by Wyndham Greenville Woodruff Rd
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Red Roof Inn Spartanburg – I-26

Red Roof Inn Spartanburg – I-26

2 out of 5
6765 Pottery Rd, Spartanburg, SC
$66 nightly
The price is $73 total per night from Jun 18 to Jun 19
$73 total
Jun 18 - Jun 19
Total includes taxes and fees
Stay at this hotel in Spartanburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions County University Soccer Stadium and Susan Jacobs Arboretum ...
6.8/10 (706 reviews)
"Fine budget accommodation."

Reviewed on Apr 1, 2025

Red Roof Inn Spartanburg – I-26
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top Upstate South Carolina with Airport Shuttles

Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road, Greenville, SC
$70 nightly
The price is $77 total per night from Jun 4 to Jun 5
$77 total
Jun 4 - Jun 5
Total includes taxes and fees
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,000 reviews)
Cant beat the value
"Pool was under reno while we were there. Not a huge deal but would have liked a heads up. Checkin was easy and the lady was very friendly. We used express check out. The room was clean and in good condition. Other than airport (planes) and a few sirens (firehouse near by) ot was pretty peaceful. ..."

Reviewed on May 27, 2025

Best Western Greenville Airport Inn
Courtyard Greenville-Spartanburg by Marriott

Courtyard Greenville-Spartanburg by Marriott

3 out of 5
115 The Pkwy, Greer, SC
$124 nightly
The price is $136 total per night from Jul 4 to Jul 5
$136 total
Jul 4 - Jul 5
Total includes taxes and fees
Stay at this 3-star business-friendly hotel in Greer. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (588 reviews)
"Great value, friendly staff!"

Reviewed on May 29, 2025

Courtyard Greenville-Spartanburg by Marriott
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd, Greenville, SC
$107 nightly
The price is $118 total per night from Jun 29 to Jun 30
$118 total
Jun 29 - Jun 30
Total includes taxes and fees
Stay at this 3.5-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room ...
8.4/10 Very Good! (1,009 reviews)
"Great place to stay. Very convenient to downtown Greenville. Our room was very clean and comfortable. Beautiful hotel and pleasant, helpful staff. Thoroughly enjoyed our stay."

Reviewed on Jun 2, 2025

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
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Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd, Greenville, SC
$141 nightly
The price is $155 total per night from Jun 15 to Jun 16
$155 total
Jun 15 - Jun 16
Total includes taxes and fees
Stay at this 3.5-star golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,002 reviews)
"Great stay! My kids really enjoyed it. Clean rooms."

Reviewed on May 27, 2025

Embassy Suites Greenville Golf Resort & Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Upstate South Carolina

The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St, Greenville, SC
$184 nightly
The price is $203 total per night from Jun 29 to Jun 30
$203 total
Jun 29 - Jun 30
Total includes taxes and fees
Stay at this 4-star business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the ...
9.2/10 Wonderful! (1,001 reviews)
"Very nice"

Reviewed on May 29, 2025

The Westin Poinsett Greenville
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St, Greenville, SC
$131 nightly
The price is $144 total per night from Jun 30 to Jul 1
$144 total
Jun 30 - Jul 1
Total includes taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,006 reviews)
"Was a wonderful stay. Staff was so friendly and such a perfect location. We'll be back for sure!"

Reviewed on May 31, 2025

Hyatt Regency Greenville
Sleep Inn at Greenville Convention Cente

Sleep Inn at Greenville Convention Cente

2.5 out of 5
231 N Pleasantburg Dr, Greenville, SC
$87 nightly
The price is $96 total per night from Jun 6 to Jun 7
$96 total
Jun 6 - Jun 7
Total includes taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (975 reviews)
Fine for the price
"It’s fine. Nothing special. Bed wasn’t particularly comfortable."

Reviewed on Jun 1, 2025

Sleep Inn at Greenville Convention Cente
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The Bleckley Inn

The Bleckley Inn

3.5 out of 5
151 E Church St, Anderson, SC
$190 nightly
The price is $211 total per night from Jun 22 to Jun 23
$211 total
Jun 22 - Jun 23
Total includes taxes and fees
Stay at this 3.5-star business-friendly hotel in Anderson. Enjoy free parking, a rooftop terrace, and a fitness center. Popular attractions Church Street Heritage ...
9.6/10 Exceptional! (398 reviews)
"Beautiful hotel in beautiful downtown Anderson."

Reviewed on May 9, 2025

The Bleckley Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Upstate South Carolina

Embassy Suites by Hilton Greenville Downtown Riverplace

Embassy Suites by Hilton Greenville Downtown Riverplace

3.5 out of 5
250 Riverplace, Greenville, SC
$156 nightly
The price is $171 total per night from Jun 29 to Jun 30
$171 total
Jun 29 - Jun 30
Total includes taxes and fees
Stay at this 3.5-star business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the breakfast and the bar ...
9/10 Wonderful! (1,002 reviews)
"It was a wonderful trip! The hotel was very clean, nice, and the reception people were very friendly! Great roof top bar! See picture of view from bar."

Reviewed on May 30, 2025

Embassy Suites by Hilton Greenville Downtown Riverplace
Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road, Greenville, SC
$70 nightly
The price is $77 total per night from Jun 4 to Jun 5
$77 total
Jun 4 - Jun 5
Total includes taxes and fees
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,000 reviews)
Cant beat the value
"Pool was under reno while we were there. Not a huge deal but would have liked a heads up. Checkin was easy and the lady was very friendly. We used express check out. The room was clean and in good condition. Other than airport (planes) and a few sirens (firehouse near by) ot was pretty peaceful. ..."

Reviewed on May 27, 2025

Best Western Greenville Airport Inn
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd, Greenville, SC
$141 nightly
The price is $155 total per night from Jun 15 to Jun 16
$155 total
Jun 15 - Jun 16
Total includes taxes and fees
Stay at this 3.5-star golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,002 reviews)
"Great stay! My kids really enjoyed it. Clean rooms."

Reviewed on May 27, 2025

Embassy Suites Greenville Golf Resort & Conference Center
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Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC

2.5 out of 5
116 Interstate Blvd, Anderson, SC
$110 nightly
The price is $122 total per night from Jul 2 to Jul 3
$122 total
Jul 2 - Jul 3
Total includes taxes and fees
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (1,000 reviews)
"I have stayed at this hotel before and have never had any problems with it or the staff. Very nice, clean, and great vibes from everyone."

Reviewed on May 27, 2025

Country Inn & Suites by Radisson, Anderson, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Upstate South Carolina Flight and Hotel Packages

Upstate South Carolina flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Zelda Dearest
Elevation Lofts Hotel
The Restoration Asheville
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See all available trips from Orlando to Upstate South Carolina
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Upstate South Carolina flight + hotel packages - premium economy flights

Price found within the past 48 hours. Click for updated prices.
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
The Shepherd Hotel Downtown Clemson
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See all available trips from Orlando to Upstate South Carolina
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Need a Car For After Your Flight?

Plane Tickets To Upstate South Carolina

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Upstate South Carolina. Browse through our inventory to explore a wide range of cheap flights to Upstate South Carolina to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Upstate South Carolina as you anxiously await to exit the plane and explore what Upstate South Carolina has to offer. Considering all the amazing local food and culture in Upstate South Carolina, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Upstate South Carolina to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Upstate South Carolina without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Upstate South Carolina with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Upstate South Carolina today!

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.