Southeast Missouri , MO Pet Friendly Hotels
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Top Southeast Missouri Pet Friendly Hotels
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $110 total per night from Nov 21 to Nov 22
$110 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.4/10 Exceptional! (1,000 reviews)
The room was very clean. The front desk staff were courteous and helpful.
Reviewed on Nov 9, 2025
Pear Tree Inn Sikeston
2602 E Malone Avenue Sikeston MO
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $89 total per night from Nov 30 to Dec 1
$89 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.2/10 Wonderful! (1,000 reviews)
Grat as usual!
Reviewed on Nov 11, 2025
Drury Inn & Suites Poplar Bluff
2220 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Nov 21 to Nov 22
$106 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.2/10 Wonderful! (945 reviews)
The only thing was food was left on the fridge. Otherwise, excellent service and condition!
Reviewed on Nov 14, 2025
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Nov 23 to Nov 24
$79 total
Nov 23 - Nov 24
Total with taxes and fees
Free WiFi in public areas and express check-out are available at this hotel. Staff at the 24-hour front desk can provide around-the-clock assistance.
8.8/10 Excellent! (1,000 reviews)
good
Reviewed on Nov 12, 2025
Microtel Inn & Suites by Wyndham Sainte Genevieve
21958 Hwy 32 Ste Genevieve MO
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $86 total per night from Nov 23 to Nov 24
$86 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
8.6/10 Excellent! (606 reviews)
Excellent
Reviewed on Nov 14, 2025
Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $80 total per night from Nov 18 to Nov 19
$80 total
Nov 18 - Nov 19
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage is provided and the front desk is staffed ...
7.8/10 Good! (1,006 reviews)
Exceptionally clean. Great location with easy access to highway. Friendly staff. Dog was free, which was a great bonus. Coffee wasn't available in the morning. Top sheets on the bed were so full of static we couldn't use them - would be much better to have 100% cotton sheets rather than polyester. ...
Reviewed on Nov 12, 2025
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
1001 Veterans Blvd Festus MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $112 total per night from Nov 23 to Nov 24
$112 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7.8/10 Good! (878 reviews)
One of the quietest hotels I’ve ever stayed in. The staff is amazing as well. The rooms are clean, the beds are comfortable and everything is literally right there. A front desk worker named Jessica helped me out with something going above and beyond. This hotel deserves all the business.
Reviewed on Nov 11, 2025
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $72 total per night from Nov 23 to Nov 24
$72 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
7.2/10 Good! (1,000 reviews)
Nice room, but no trash can, no hot water in bathroom sink. No comfortable chair. No ice bucket.
Reviewed on Nov 11, 2025
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See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Pet Friendly Hotel in Southeast Missouri
It’s hard to leave for a trip when the last image you have is of your four-legged best friend staring out the living-room window with those sad eyes as you drive away. You don’t have to leave Spot behind any longer, he can finally join you on your adventures.
Turn your trip into a family getaway by booking a stay at one of the pet-friendly hotels in Southeast Missouri for you and your furry kids. No more sending them to pet hotels or leaving them home alone to run amok in the house. Southeast Missouri pet-friendly hotels are perfect for weekend escapes with your pooch, kitty, bird, or fish. These accommodations not only welcome your pets, but they offer many services to help make your stay more relaxing. Things like on-site grooming and complimentary dog walking are some of the amenities provided. In most cases, you’ll also be near outdoor spaces like dog parks if you both need some exercise, as well as pet-friendly restaurants.
Don’t ever feel guilty about leaving your beloved Maximus behind on a trip again. Travelocity wants to help the both of you enjoy a wonderful vacation together. Search our extensive inventory of the best pet-friendly hotels in Southeast Missouri and book your stay now.
Southeast Missouri hotels essential information
Accommodation | 610 hotels |
|---|---|
Lowest Price | $72 |
Highest Price | $112 |
Popular hotels | Motel 6 Poplar Bluff, MO, Microtel Inn & Suites by Wyndham Sainte Genevieve, La Quinta Inn & Suites by Wyndham Festus - St. Louis South, Drury Inn & Suites Sikeston, MO, Pear Tree Inn Sikeston, Drury Inn & Suites Poplar Bluff, Days Inn and Suites by Wyndham Sikeston, Pear Tree Inn Cape Girardeau Near the Medical Center |
Recent Southeast Missouri hotel reviews by fellow wanderers
Pear Tree Inn Cape Girardeau Near the Medical Center
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"good"
A verified traveler stayed at Pear Tree Inn Cape Girardeau Near the Medical Center
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