Southeast Missouri , MO Pet Friendly Hotels
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Top Southeast Missouri Pet Friendly Hotels
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $103 total per night from Jan 11 to Jan 12
$103 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.4/10 Exceptional! (1,005 reviews)
The room was very nice and the bathroom was very clean. Everything was very nice and the breakfast was good. We were very pleased with everything. I recommend it highly.
Reviewed on Jan 2, 2026
Pear Tree Inn Sikeston
2602 E Malone Avenue Sikeston MO
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $86 total per night from Jan 11 to Jan 12
$86 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.2/10 Wonderful! (1,006 reviews)
Everything was good. Clean, fast internet. Good food. Friendly staff.
Reviewed on Jan 3, 2026
Drury Inn & Suites Poplar Bluff
2220 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Jan 16 to Jan 17
$106 total
Jan 16 - Jan 17
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.2/10 Wonderful! (972 reviews)
Clean and friendly.
Reviewed on Dec 30, 2025
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jan 11 to Jan 12
$79 total
Jan 11 - Jan 12
Total with taxes and fees
Free WiFi in public areas and express check-out are available at this hotel. Staff at the 24-hour front desk can provide around-the-clock assistance.
8.8/10 Excellent! (1,003 reviews)
Everything was wonderful. Staff (especially Debbie) was the best. This is a nice quiet comfortable pplace to stay
Reviewed on Dec 26, 2025
Microtel Inn & Suites by Wyndham Sainte Genevieve
21958 Hwy 32 Ste Genevieve MO
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $83 total per night from Jan 11 to Jan 12
$83 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
8.6/10 Excellent! (614 reviews)
The room was very clean and had a comfortable feeling to it. I liked that I could easily control the temperature in the room. The manager was responsive. However, I had to change rooms because the TV set wouldn’t work in the first room.
Reviewed on Dec 30, 2025
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $80 total per night from Jan 7 to Jan 8
$80 total
Jan 7 - Jan 8
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage is provided and the front desk is staffed ...
7.8/10 Good! (1,005 reviews)
Excellent deal for the price. The suite with two queen beds was perfect for my son and me. The man at the counter was so great to us.
Reviewed on Jan 2, 2026
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
1001 Veterans Blvd Festus MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $106 total per night from Jan 11 to Jan 12
$106 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7.8/10 Good! (899 reviews)
Clean room
Reviewed on Dec 29, 2025
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $72 total per night from Jan 11 to Jan 12
$72 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
7.2/10 Good! (1,001 reviews)
Staff was very nice. Room layout with two separate rooms was appreciated, especially at this price point. Good bed and bedding. Not super high end or careful about the rehab, and the breakfast was a carb fest, but overall we still felt it was a very good value
Reviewed on Dec 26, 2025
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Pet Friendly Hotel in Southeast Missouri
Southeast Missouri hotels essential information
Accommodation | 623 hotels |
|---|---|
Lowest Price | $72 |
Highest Price | $106 |
Popular hotels | Motel 6 Poplar Bluff, MO, Microtel Inn & Suites by Wyndham Sainte Genevieve, La Quinta Inn & Suites by Wyndham Festus - St. Louis South, Drury Inn & Suites Sikeston, MO, Pear Tree Inn Sikeston, Drury Inn & Suites Poplar Bluff, Days Inn and Suites by Wyndham Sikeston, Pear Tree Inn Cape Girardeau Near the Medical Center |
Recent Southeast Missouri hotel reviews by fellow wanderers
Motel 6 Poplar Bluff, MO
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Excellent deal for the price. The suite with two queen beds was perfect for my son and me. The man at the counter was so great to us."
A verified traveler stayed at Motel 6 Poplar Bluff, MO
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