Book Kid-Friendly Hotels in Southeast Missouri from $61

Name: Comfort Suites Jackson-Cape Girardeau
Price range: $94 total
Rating: 8

Find & compare hotels, resorts and vacation rentals for the whole family

Top Southeast Missouri Kid Friendly Hotels

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner, Sikeston, MO

Fully refundableReserve now, pay when you stay

$99 nightly

$114 total

Jun 1 - Jun 2

Total includes taxes and fees

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...

9.4/10 Exceptional! (1,004 reviews)

"The room was clean, well maintained and uncluttered. Breakfast was included in the room price. There was a wide variety of food options: fresh scrambled eggs, sausage, potatoes, oatmeal and yogurt. Many more options but those are the ones I remember. Fresh coffee and fountain sodas were also available. ..."

Reviewed on May 27, 2025

Drury Inn & Suites Jackson MO

225 Drury Lane, Jackson, MO

Fully refundableReserve now, pay when you stay

$90 nightly

$95 total

Jun 1 - Jun 2

Total includes taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...

9.4/10 Exceptional! (1,001 reviews)

"The accessibility rooms are some distance from the elevator and ice machines are limited to specific floors"

Reviewed on May 21, 2025

Pear Tree Inn Sikeston

2602 E Malone Avenue, Sikeston, MO

Fully refundableReserve now, pay when you stay

$85 nightly

$98 total

Jun 1 - Jun 2

Total includes taxes and fees

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...

9.2/10 Wonderful! (1,009 reviews)

"Enjoyed the kick bax and relax. Friendly staff."

Reviewed on May 26, 2025

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Drury Inn & Suites Cape Girardeau

3303 Campster Drive, Cape Girardeau, MO

Fully refundableReserve now, pay when you stay

$94 nightly

$107 total

Jun 1 - Jun 2

Total includes taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...

9.2/10 Wonderful! (932 reviews)

"Room was very clean and staff was excellent!"

Reviewed on May 25, 2025

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

1802 Gamel Cemetery Road, Festus, MO

Fully refundable

$139 nightly

$159 total

Jun 1 - Jun 2

Total includes taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...

9.2/10 Wonderful! (641 reviews)

"You will need a car to go anywhere here in Festus. But that is not the hotels fault. Breakfast was delicious."

Reviewed on May 21, 2025

Drury Inn & Suites Hayti Caruthersville

1317 E Highway 84, Hayti, MO

Fully refundableReserve now, pay when you stay

$99 nightly

$113 total

Jun 2 - Jun 3

Total includes taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...

9.2/10 Wonderful! (1,003 reviews)

"Everything was great except the breakfast did not offer enough healthy lifestyle food."

Reviewed on May 26, 2025

Best Western Plus Sikeston

120 S Interstate Drive, Sikeston, MO

Fully refundableReserve now, pay when you stay

$84 nightly

$96 total

Jun 8 - Jun 9

Total includes taxes and fees

This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...

8.2/10 Very Good! (1,001 reviews)

Amazing value

"Very clean and comfortable beds. Great selection for free breakfast"

Reviewed on May 23, 2025

Comfort Suites Jackson-Cape Girardeau

2904 Old Orchard Rd, Jackson, MO

Fully refundableReserve now, pay when you stay

$87 nightly

$94 total

May 29 - May 30

Total includes taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...

8/10 Very Good! (710 reviews)

"I was only there for 5 hours to sleep. It was cozy and clean. I only wish I had more time to rest in my bed. I’m not sure what the surrounding area was like - probably not wonderful, but there was a police car stationed outside between our hotel and the next hotel. Everything outside was well lit, ..."

Reviewed on Apr 28, 2025

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels With Pools in Southeast Missouri

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner, Sikeston, MO

$99 nightly

$114 total

Jun 1 - Jun 2

Total includes taxes and fees

9.4/10 Exceptional! (1,004 reviews)

Book a stay at the best kid-friendly hotels in Southeast Missouri

How much does it cost to stay in a family hotel in Southeast Missouri?

You can book a stay at a kid-friendly resort in Southeast Missouri from just $61 per night. Our prices range up $159 per night if you want to enjoy the high life.

How many family-friendly hotels are there in Southeast Missouri?

With over 572 hotels in Southeast Missouri, you have a great selection of kid-friendly places to stay. Whether you’re looking for a cheap-and-cheerful property with plenty of space or an activity-filled kid-friendly resort, there’s a getaway to suit your style and your budget at Travelocity.

What is Travelocity’s cancellation policy for family hotels in Southeast Missouri?

We offer free cancellation on select hotels. Policies can vary per property so it's best to check before you book. If you need to amend or cancel your vacation, just visit our Customer Service Portal. 

What are the best kid-friendly hotels in Southeast Missouri?

At Travelocity, you can book the best family-friendly Southeast Missouri hotel for you and your family by filtering your search by price, property type, and a range of amenities such as breakfast included or free airport shuttle. Use the map to see where the hotels are and the attractions they’re near.

What should I expect in the family-friendly hotels in Southeast Missouri?

When you book a kid-friendly Southeast Missouri resort, you can expect fun for all the family. Think pools, waterparks, and hot tubs. Think babysitting, kids’ menus, games rooms, and sport facilities—discover your ideal family vacation. Many resorts keep the kids happy, so you can indulge in bars, restaurants, and spas. Check details for each property as offers may vary.

How can I find family hotel deals in Southeast Missouri?

Just enter your travel dates and sort your results by price. You can even filter your results by budget, so you’ll only see the deals that are right for your pocket. It’s easy to find great deals on family-friendly hotels in Southeast Missouri with Travelocity. 

When is the cheapest time to go to Southeast Missouri with your family?

The cheapest time to visit Southeast Missouri is usually .

When is the best time to go to Southeast Missouri with your kids?

The most popular months are and are great for booking in at a Southeast Missouri kid-friendly resort. If you want a quieter vacation—or the kids aren’t in school yet— are usually less busy, but you can find incredible deals all year round with Travelocity. 

Why book a Southeast Missouri child-friendly hotel with Travelocity?

Because we search the entire market, so you don’t have to. You’ll find great deals on everything from weekend trips to two-week family vacations. Whatever your budget or your wish list, we’ve got what you’re looking for.

Popular places to visit

Taum Sauk Mountain in located in the St.Francis mountain range of south/central Missouri. It's also the highest point in Missouri. My kids are standing at the spot where the actual marker sign in

Elephant Rocks State Park

5/5(13 reviews)

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

Southeast Missouri hotels essential information

Accommodation	572 hotels
Lowest Price	$61
Highest Price	$159
Popular hotels	Drury Inn & Suites Sikeston, MO, Pear Tree Inn Sikeston, Best Western Plus Sikeston, Drury Inn & Suites Cape Girardeau, Comfort Suites Jackson-Cape Girardeau, Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG, Drury Inn & Suites Jackson MO, Drury Inn & Suites Hayti Caruthersville

Package deals, things to do & more in Southeast Missouri

Recent Southeast Missouri Hotel Reviews By Fellow Wanderers

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

5 out of 5

Posted 19 hours ago

Travelocity Verified Review

"I thought the property was very clean and appealing. Our check in clerk for our 1st night stay on May 22nd was very friendly, and helpful, however our 2nd stay on May 25th our clerk was unpleasant never said hello never smiled. She wasn't rude but she seemed very unfriendly and like she didn't want to be there. But our rooms were very clean, the breakfast was good, and the breakfast staff was very friendly as well. I would definitely stay here again in the future."

A verified traveler stayed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG