Find & compare spa resorts in Southeast Missouri, MO from $63

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Top Southeast Missouri Spa Resorts & Hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southeast Missouri Spa Hotels

Are you looking for a break from the hustle and bustle of your day-to-day life? Do you want to escape reality and forget about your never ending to-do list? Then why not treat yourself to a relaxing stay at one of the spa hotels in Southeast Missouri? Whether it is for a weekend getaway or a staycation, book your visit to one of the Southeast Missouri luxury spa hotels.

With all of the amazing things to do around Southeast Missouri, you will likely be worn out from sightseeing. The Southeast Missouri spa hotels provide top of the line facilities with hot-tubs, saunas and private treatment rooms. Treat yourself to an indulgent hot stone massage or facial to rejuvenate from a busy day. If that's not enough for you, indulge in a full day-at-the-spa package. And maybe you are just looking to reach maximum relaxation before a fancy night out on the town. Take advantage of the salon features offered at most Southeast Missouri spa hotels and get a mani-pedi before your evening begins. 

Travelocity wants to help you relax and rejuvenate during your next stay in Southeast Missouri, but we know that spa treatments can put some strain on your wallet. Bundle your hotel and flight together and save enough to pay for your facial!

Southeast Missouri hotels essential information

Accommodation
568 hotels
Lowest Price
$63
Highest Price
$179
Popular hotels
Auburn Place Hotel And Suites, Crown Pointe Lodge, BW Signature Collection, Drury Inn & Suites Cape Girardeau, Drury Inn & Suites Hayti Caruthersville, Drury Inn & Suites Jackson MO, Drury Inn & Suites Poplar Bluff, Drury Plaza Hotel Cape Girardeau Conference Center, Eagle Inn Charleston, Hampton Inn Farmington, Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel, Super 8 by Wyndham Perryville, Super 8 by Wyndham Pevely

Recent Southeast Missouri hotel reviews by fellow wanderers