Book Hotels in Perryville, MO
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Top Perryville hotels

New! Luxury Meets Nature - TreeRise at BaseCamp
Perryville MO
$503 nightly
The price is $529 total per night from Jul 5 to Jul 6
$529 total
Jul 5 - Jul 6
Total with taxes and fees
A hot tub is featured at this cabin, along with laundry facilities and barbecue grills.
"Everything was perfect! Kaci and Waylon thought of everything. Can’t wait to come back!"
Reviewed on Apr 19, 2026

The Atrium - A Boutique Hotel
112 W Ste Maries St Perryville MO
$137 nightly
The price is $157 total per night from Aug 3 to Aug 4
$157 total
Aug 3 - Aug 4
Total with taxes and fees
This aparthotel features a virtual front desk. Take advantage of the free self parking.
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. ..."
Reviewed on Jun 13, 2026

Hot Tub & Creek Views: Secluded Perryville Cabin
Perryville MO
A hot tub is featured at this cabin, along with laundry facilities and barbecue grills.
"If you need to reset and recharge, this is the place!!The property is lovely, the house is surrounded by woods and fields. The house is unique and rustic and interesting. The bathrooms and kitchen are updated and the beds are very comfy.No better place to porch sit and enjoy nature. It was a fun ..."
Reviewed on May 14, 2026

Urban Lofts
102 N Jackson St Perryville MO
Fully refundableReserve now, pay when you stay
$295 nightly
The price is $338 total per night from Jul 5 to Jul 6
$338 total
Jul 5 - Jul 6
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Dry cleaning, luggage storage, and laundry facilities are also on ...
"Beautiful, clean property in the heart of city center. Many options for food and shopping within short walking distance."
Reviewed on Jun 11, 2026

Holiday Inn Express & Suites Perryville by IHG
2020 Jefferson St Perryville MO
Fully refundable
$101 nightly
The price is $116 total per night from Jul 6 to Jul 7
$116 total
Jul 6 - Jul 7
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Family of 4 . 1 night stay Great stay, would stay again"
Reviewed on Jul 1, 2026

Super 8 by Wyndham Perryville
1119 Vincent Dr Perryville MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $78 total per night from Jul 29 to Jul 30
$78 total
Jul 29 - Jul 30
Total with taxes and fees
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Pleasant welcoming. Clean rooms and facilities. Breakfast was good."
Reviewed on Jul 3, 2026

Days Inn by Wyndham Perryville
1500 Liberty Street Perryville MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $77 total per night from Jul 5 to Jul 6
$77 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"I don’t have any idea where the bad reviews are coming from. The hotel was clean. Staff was inviting. Location is right off I-55 by plenty of other businesses. We came in at night after deciding to take a break from driving & had looked for a cheaper hotel. The room was spacious & clean. A/C worked ..."
Reviewed on Jun 26, 2026

Quality Inn Perryville I-55
1517 S. Perryville Blvd. Perryville MO
Fully refundable
$76 nightly
The price is $87 total per night from Jul 6 to Jul 7
$87 total
Jul 6 - Jul 7
Total with taxes and fees
This hotel features an outdoor pool and a gym. Enjoy the hot tub and free perks like daily breakfast and free self parking. The front desk is staffed around-the-clock ...

TreeLoft at BaseCamp
Perryville MO
$503 nightly
The price is $529 total per night from Jul 19 to Jul 20
$529 total
Jul 19 - Jul 20
Total with taxes and fees
A hot tub is featured at this cabin, along with a garden and barbecue grills.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Perryville with star-rating
Check Perryville Hotels by Star Rating

4 Star Hotels
1 properties
Frequently asked questions
Recent Perryville hotel reviews by fellow wanderers

Super 8 by Wyndham Perryville
4 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Pleasant welcoming. Clean rooms and facilities. Breakfast was good."
A verified traveler stayed at Super 8 by Wyndham Perryville
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