Hotels with Restaurants in Southeast Missouri from $62
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Top Southeast Missouri Hotels with Restaurants
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Cape Girardeau MO
This apartment features a water park, laundry facilities, and barbecue grills.
Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Free Cancellation
Reserve now, pay when you stay
$83 nightly
The price is $88 total per night
$88 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Hampton Inn Cape Girardeau I 55 East
207 S Mt Auburn Rd Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
$99 nightly
The price is $112 total per night
$112 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $103 total per night
$103 total
Dec 15 - Dec 16
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $102 total per night
$102 total
Dec 15 - Dec 16
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Drury Inn & Suites Hayti Caruthersville
1317 E Highway 84 Hayti MO
Free Cancellation
Reserve now, pay when you stay
$94 nightly
The price is $107 total per night
$107 total
Dec 19 - Dec 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Drury Inn & Suites Poplar Bluff
2220 N Westwood Blvd Poplar Bluff MO
Free Cancellation
Reserve now, pay when you stay
$94 nightly
The price is $106 total per night
$106 total
Dec 15 - Dec 16
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Hampton Inn Poplar Bluff
2420 Crestwood Dr Poplar Bluff MO
Free Cancellation
Reserve now, pay when you stay
$93 nightly
The price is $104 total per night
$104 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business ...
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
$70 nightly
The price is $79 total per night
$79 total
Dec 15 - Dec 16
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
Holiday Inn Poplar Bluff by IHG
2781 N Westwood Blvd Poplar Bluff MO
Free Cancellation
$105 nightly
The price is $119 total per night
$119 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Best Western Plus Sikeston
120 S Interstate Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$71 nightly
The price is $81 total per night
$81 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
$54 nightly
The price is $62 total per night
$62 total
Dec 17 - Dec 18
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southeast Missouri hotels essential information
Accommodation | 619 hotels |
|---|---|
Lowest Price | $62 |
Highest Price | $119 |
Popular hotels | Drury Inn & Suites Hayti Caruthersville, Drury Inn & Suites Jackson MO, Drury Inn & Suites Sikeston, MO, Hampton Inn Cape Girardeau I 55 East, Drury Inn & Suites Poplar Bluff, Baymont Inn and Suites by Wyndham Farmington, MO, Holiday Inn Poplar Bluff by IHG, Best Western Plus Sikeston, Pear Tree Inn Cape Girardeau West, Drury Plaza Hotel Cape Girardeau Conference Center, Hampton Inn Poplar Bluff, Historical 'Kage House' Short Term Rental located in "Old Town Cape" |
Recent Southeast Missouri hotel reviews by fellow wanderers
Drury Plaza Hotel Cape Girardeau Conference Center
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Beds were great. Very clean all around. Very nice breakfast with glutten free bread for my wife.
"
A verified traveler stayed at Drury Plaza Hotel Cape Girardeau Conference Center
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