Explore 41 Luxury Hotels in Southern Indiana

Name: Baymont by Wyndham Corydon
Price range: $76 total
Rating: 7.4

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Best Luxury Hotels in Southern Indiana

21c Museum Hotel Louisville

700 W Main Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$125 nightly

$147 total

Aug 10 - Aug 11

Total includes taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.2/10 Wonderful! (1,001 reviews)

"Great Location. Great hotel. Great team members."

Reviewed on Jul 14, 2025

The Brown Hotel

335 W Broadway, Louisville, KY

Fully refundableReserve now, pay when you stay

$179 nightly

$211 total

Jul 27 - Jul 28

Total includes taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...

9.2/10 Wonderful! (1,032 reviews)

"The hotel itself is historic and so beautiful. We ate at both restaurants during our stay and had great experiences. The rooms were clean but had a very moist, damp feel throughout the stay. They could use some updating to the fixtures, painting, etc. Rhe bed was very firm but my husband was very ..."

Reviewed on Jul 21, 2025

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$138 nightly

$162 total

Aug 10 - Aug 11

Total includes taxes and fees

A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

8.8/10 Excellent! (3,464 reviews)

"Prompt and friendly response to all questions."

Reviewed on Jul 20, 2025

Embassy Suites Louisville Downtown

501 South Fourth Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$119 nightly

$140 total

Aug 10 - Aug 11

Total includes taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and WiFi in public areas. Valet ...

8.8/10 Excellent! (1,003 reviews)

"Very nice will stay again . Very friendly staff very clean . Only complaint is the bed was hard and the ac took forever to cool the room down"

Reviewed on Jul 20, 2025

Seelbach Hilton Louisville Downtown

500 S 4th St, Louisville, KY

Fully refundableReserve now, pay when you stay

$168 nightly

$198 total

Jul 26 - Jul 27

Total includes taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...

8.6/10 Excellent! (1,001 reviews)

Wedding weekend

"Charming beautiful hotel . Excellent location to walk to all attractions."

Reviewed on Jul 13, 2025

Baymont by Wyndham Corydon

2495 Landmark Avenue NE, Corydon, IN

Fully refundableReserve now, pay when you stay

$69 nightly

$76 total

Jul 27 - Jul 28

Total includes taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...

7.4/10 Good! (1,003 reviews)

"Great place quite. and staff was excellent at the desk"

Reviewed on Jul 15, 2025

Econo Lodge Downtown Louisville

401 S 2nd St, Louisville, KY

Fully refundableReserve now, pay when you stay

$58 nightly

$69 total

Aug 12 - Aug 13

Total includes taxes and fees

This motel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the express check-out. ...

7.2/10 Good! (1,003 reviews)

"Perfect affordable place to stay! It is such a convenient location within walking distance of many nearby businesses, friendly staff, clean room with a BALCONY that I was not expecting. Noisy road is my only complaint, and that’s the price you pay for being so close to everything, so it’s worth it ..."

Reviewed on Jul 7, 2025

West Baden Springs Hotel

8538 W Baden Ave, West Baden Springs, IN

This luxury resort features a casino, a full-service spa, and 15 restaurants. Bring the family and enjoy the children's club, along with horse riding/rentals. ...

"The hotel West Baden is awesome they have 24 hour trolley that runs every 15 minutes and will take you anywhere in the area."

Reviewed on Dec 25, 2018

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Southern Indiana

Stellar Suites

822 E Market St, Louisville, KY

$159 nightly

$185 total

Aug 9 - Aug 10

Total includes taxes and fees

9.6/10 Exceptional! (99 reviews)

Southern Indiana Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southern Indiana luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Southern Indiana to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Southern Indiana will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southern Indiana, and plan your next opulent escape.

Southern Indiana hotels essential information

Accommodation	1,449 hotels
Lowest Price	$69
Highest Price	$239
Popular hotels	21c Museum Hotel Louisville, West Baden Springs Hotel, The Brown Hotel, Galt House Hotel Trademark Collection by Wyndham, Embassy Suites Louisville Downtown, Econo Lodge Downtown Louisville, Seelbach Hilton Louisville Downtown, Baymont by Wyndham Corydon

Popular Luxury Stays in Southern Indiana

5 Stars Luxury stays in Southern Indiana

Luxury stays in Southern Indiana with spa

Recent Southern Indiana Hotel Reviews By Fellow Wanderers

Howard Johnson by Wyndham Evansville East

5 out of 5

Posted 2 days ago

Travelocity Verified Review

"The staff was great and the room is an excellent value for the money with a yummy breakfast! Our dog also loved the doggie daycare/boarding facility across the street while we were out with family."

A verified traveler stayed at Howard Johnson by Wyndham Evansville East